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PHLPP (PHLPP1) (NM_194449) Human Tagged ORF Clone Lentiviral Particle
CAT＃: RC203930L1V
- LentiORF®
-
Lenti ORF particles, PHLPP1 (Myc-DDK tagged) - Human PH domain and leucine rich repeat protein phosphatase 1 (PHLPP1), 200ul, >10^7 TU/mL
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CNY 21,660.00
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规格
| Cited in 1 publication. |
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经常一起买 (3)
Specifications
| Product Data | |
| Product Name | PHLPP (PHLPP1) (NM_194449) Human Tagged ORF Clone Lentiviral Particle |
| Synonyms | PHLPP; PLEKHE1; PPM3A; SCOP |
| Vector | pLenti-C-Myc-DDK |
| ACCN | NM_194449 |
| ORF Size | 3615 bp |
| Sequence Data |
The ORF insert of this clone is exactly the same as(RC203930).
|
| OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
| Reference Data | |
| RefSeq | NM_194449.1, NP_919431.1 |
| RefSeq Size | 4798 bp |
| RefSeq ORF | 5154 bp |
| Locus ID | 23239 |
| MW | 184.5 kDa |
| Gene Summary | This gene encodes a member of the serine/threonine phosphatase family. The encoded protein promotes apoptosis by dephosphorylating and inactivating the serine/threonine kinase Akt, and functions as a tumor suppressor in multiple types of cancer. Increased expression of this gene may also play a role in obesity and type 2 diabetes by interfering with Akt-mediated insulin signaling. [provided by RefSeq, Dec 2011] |
Citations (1)
| The use of this cDNA Clones has been cited in the following citations: |
|---|
|
PHLPP1 splice variants differentially regulate AKT and PKC? signaling in hippocampal neurons: characterization of PHLPP proteins in the adult hippocampus
,null,
Journal of neurochemistry
,PubMed ID 20819118
[PHLPP1]
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