United States
Germany
Japan
United Kingdom
China
PEN2 (PSENEN) (NM_172341) Human Tagged ORF Clone Lentiviral Particle
CAT＃: RC203272L2V
- LentiORF®
-
Lenti ORF particles, PSENEN (mGFP-tagged) - Human presenilin enhancer 2 homolog (C. elegans) (PSENEN), 200ul, >10^7 TU/mL
Need custom lentivirus service?
Get a free quote
CNY 8,360.00
货期*
详询
规格
Product images
经常一起买 (3)
Specifications
| Product Data | |
| Product Name | PEN2 (PSENEN) (NM_172341) Human Tagged ORF Clone Lentiviral Particle |
| Synonyms | ACNINV2; MDS033; MSTP064; PEN-2; PEN2 |
| Vector | pLenti-C-mGFP |
| ACCN | NM_172341 |
| ORF Size | 303 bp |
| Sequence Data |
The ORF insert of this clone is exactly the same as(RC203272).
|
| OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
| Reference Data | |
| RefSeq | NM_172341.1 |
| RefSeq Size | 834 bp |
| RefSeq ORF | 306 bp |
| Locus ID | 55851 |
| Protein Families | Druggable Genome, Transmembrane |
| Protein Pathways | Alzheimer's disease, Notch signaling pathway |
| MW | 12 kDa |
| Gene Summary | Presenilins, which are components of the gamma-secretase protein complex, are required for intramembranous processing of some type I transmembrane proteins, such as the Notch proteins and the beta-amyloid precursor protein. Signaling by Notch receptors mediates a wide range of developmental cell fates. Processing of the beta-amyloid precursor protein generates neurotoxic amyloid beta peptides, the major component of senile plaques associated with Alzheimer's disease. This gene encodes a protein that is required for Notch pathway signaling, and for the activity and accumulation of gamma-secretase. Mutations resulting in haploinsufficiency for this gene cause familial acne inversa-2 (ACNINV2). Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2013] |
Documents
| Product Manuals |
| FAQs |
| SDS |
Resources
You may also need
Customer
Reviews
Loading...
