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Metabotropic Glutamate Receptor 5 (GRM5) (NM_001143831) Human Untagged Clone
CAT＃: SC326357
GRM5 (untagged)-Human glutamate receptor, metabotropic 5 (GRM5), transcript variant a
CNY 8,448.00
Product images
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | GPRC1E; mGlu5; MGLUR5; PPP1R86 |
| Vector | pCMV6-XL6 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data |
>OriGene sequence for NM_001143831 edited
CAGCCAAGGCCGCTACGAGAGCGCAGGAAGCCCTCGAGGAGCGGCTGCCAGGGGGCGCAC GGCTCAGGGCGCGCACCTGGTTTAGAAGATCATGACCACATGGATCATCTAACTAAATGG TACATGGGGACAAAATGGTCCTTTAGAAAATACATCTGAATTGCTGGCTAATTTCTTGAT TTGCGACTCAACGTAGGACATCGCTTGTTCGTAGCTATCAGAACCCTCCTGAATTTTCCC CACCATGCTATCTTTATTGGCTTGAACTCCTTTCCTAAAATGGTCCTTCTGTTGATCCTG TCAGTCTTACTTTTGAAAGAAGATGTCCGTGGGAGTGCACAGTCCAGTGAGAGGAGGGTG GTGGCTCACATGCCGGGTGACATCATTATTGGAGCTCTCTTTTCTGTTCATCACCAGCCT ACTGTGGACAAAGTTCATGAGAGGAAGTGTGGGGCGGTCCGTGAACAGTATGGCATTCAG AGAGTGGAGGCCATGCTGCATACCCTGGAAAGGATCAATTCAGACCCCACACTCTTGCCC AACATCACACTGGGCTGTGAGATAAGGGACTCCTGCTGGCATTCGGCTGTGGCCCTAGAG CAGAGCATTGAGTTCATAAGAGATTCCCTCATTTCTTCAGAAGAGGAAGAAGGCTTGGTA CGCTGTGTGGATGGCTCCTCCTCTTCCTTCCGCTCCAAGAAGCCCATAGTAGGGGTCATT GGGCCTGGCTCCAGTTCTGTAGCCATTCAGGTCCAGAATTTGCTCCAGCTTTTCAACATA CCTCAGATTGCTTACTCAGCAACCAGCATGGATCTGAGTGACAAGACTCTGTTCAAATAT TTCATGAGGGTTGTGCCTTCAGATGCTCAGCAGGCAAGGGCCATGGTGGACATAGTGAAG AGGTACAACTGGACCTATGTATCAGCCGTGCACACAGAAGGCAACTATGGAGAAAGTGGG ATGGAAGCCTTCAAAGATATGTCAGCGAAGGAAGGGATTTGCATCGCCCACTCTTACAAA ATCTACAGTAATGCAGGGGAGCAGAGCTTTGATAAGCTGCTGAAGAAGCTCACAAGTCAC TTGCCCAAGGCCCGGGTGGTGGCCTGCTTCTGTGAGGGCATGACGGTGAGAGGTCTGCTG ATGGCCATGAGGCGCCTGGGTCTAGCGGGAGAATTTCTGCTTCTGGGCAGTGATGGCTGG GCTGACAGGTATGATGTGACAGATGGATATCAGCGAGAAGCTGTTGGTGGCATCACAATC AAGCTCCAATCTCCCGATGTCAAGTGGTTTGATGATTATTATCTGAAGCTCCGGCCAGAA ACAAACCACCGAAACCCTTGGTTTCAAGAATTTTGGCAGCATCGTTTTCAGTGCCGACTG GAAGGGTTTCCACAGGAGAACAGCAAATACAACAAGACTTGCAATAGTTCTCTGACTCTG AAAACACATCATGTTCAGGATTCCAAAATGGGATTTGTGATCAACGCCATCTATTCGATG GCCTATGGGCTCCACAACATGCAGATGTCCCTCTGCCCAGGCTATGCAGGACTCTGTGAT GCCATGAAGCCAATTGATGGACGGAAACTTTTGGAGTCCCTGATGAAAACCAATTTTACT GGGGTTTCTGGAGATACGATCCTATTCGATGAGAATGGAGACTCTCCAGGAAGGTATGAA ATAATGAATTTCAAGGAAATGGGAAAAGATTACTTTGATTATATCAACGTTGGAAGTTGG GACAATGGAGAATTAAAAATGGATGATGATGAAGTATGGTCCAAGAAAAGCAACATCATC AGATCTGTGTGCAGTGAACCATGTGAGAAAGGCCAGATCAAGGTGATCCGAAAGGGAGAA GTCAGCTGTTGTTGGACCTGTACACCTTGTAAGGAGAATGAGTATGTCTTTGATGAGTAC ACATGCAAGGCATGCCAACTGGGGTCTTGGCCCACTGATGATCTCACAGGTTGTGACTTG ATCCCAGTACAGTATCTTCGATGGGGTGACCCTGAACCCATTGCAGCTGTGGTGTTTGCC TGCCTTGGCCTCCTGGCCACCCTGTTTGTTACTGTAGTCTTCATCATTTACCGTGATACA CCAGTAGTCAAGTCCTCAAGCAGGGAACTCTGCTACATTATCCTTGCTGGCATCTGCCTG GGCTACTTATGTACCTTCTGCCTCATTGCGAAGCCCAAACAGATTTACTGCTACCTTCAG AGAATTGGCATTGGTCTCTCCCCAGCCATGAGCTACTCAGCCCTTGTAACAAAGACCAAC CGTATTGCAAGGATCCTGGCTGGCAGCAAGAAGAAGATCTGTACCAAAAAGCCCAGATTC ATGAGTGCCTGTGCCCAGCTAGTGATTGCTTTCATTCTCATATGCATCCAGTTGGGCATC ATCGTTGCCCTCTTTATAATGGAGCCTCCTGACATAATGCATGACTACCCAAGCATTCGA GAAGTCTACCTGATCTGTAACACCACCAACCTAGGAGTTGTCACTCCACTTGGATACAAT GGATTGTTGATTTTGAGCTGCACCTTCTATGCGTTCAAGACCAGAAATGTTCCAGCTAAC TTCAACGAGGCCAAGTATATCGCCTTCACAATGTACACGACCTGCATTATATGGCTAGCT TTTGTGCCAATCTACTTTGGCAGCAACTACAAAATCATCACCATGTGTTTCTCGGTCAGC CTCAGTGCCACAGTGGCCCTAGGCTGCATGTTTGTGCCGAAGGTGTACATCATCCTGGCC AAACCAGAGAGAAACGTGCGCAGCGCCTTCACCACATCTACCGTGGTGCGCATGCATGTA GGGGATGGCAAGTCATCCTCCGCAGCCAGCAGATCCAGCAGCCTAGTCAACCTGTGGAAG AGAAGGGGCTCCTCTGGGGAAACCTTAAGGTACAAAGACAGGAGACTGGCCCAGCACAAG TCGGAAATAGAGTGTTTCACCCCCAAAGGGAGTATGGGGAATGGTGGGAGAGCAACAATG AGCAGTTCCAATGGAAAATCCGTCACGTGGGCCCAGAATGAGAAGAGCAGCCGGGGGCAG CACCTGTGGCAGCGCCTGTCCATCCACATCAACAAGAAAGAAAACCCCAACCAAACGGCC GTCATCAAGCCCTTCCCCAAGAGCACGGAGAGCCGTGGCCTGGGCGCTGGCGCTGGCGCA GGCGGGAGCGCTGGGGGCGTGGGGGCCACGGGCGGTGCGGGCTGCGCAGGCGCCGGCCCA GGCGGGCCCGAGTCCCCAGACGCCGGCCCCAAGGCGCTGTATGATGTGGCCGAGGCTGAG GAGCACTTCCCGGCGCCCGCGCGGCCGCGCTCACCGTCGCCCATCAGCACGCTGAGCCAC CGCGCGGGCTCGGCCAGCCGCACGGACGACGATGTGCCGTCGCTGCACTCGGAGCCTGTG GCGCGCAGCAGCTCCTCGCAGGGCTCCCTCATGGAGCAGATCAGCAGTGTGGTCACCCGC TTCACGGCCAACATCAGCGAGCTCAACTCCATGATGCTGTCCACCGCGGCCCCCAGCCCC GGCGTCGGCGCCCCGCTCTGCTCGTCCTACCTGATCCCCAAAGAGATCCAGTTGCCCACG ACCATGACGACCTTTGCCGAAATCCAGCCTCTGCCGGCCATCGAAGTCACGGGCGGCGCG CAGCCCGCGGCAGGGGCGCAGGCGGCTGGGGACGCGGCCCGGGAGAGCCCCGCGGCCGGT CCCGAGGCTGCGGCCGCCAAGCCAGACCTGGAGGAGCTGGTGGCTCTCACCCCGCCGTCC CCCTTCAGAGACTCGGTGGACTCGGGGAGCACAACCCCCAACTCGCCAGTGTCCGAGTCG GCCCTCTGTATCCCGTCGTCTCCCAAATATGACACTCTTATCATAAGAGATTACACTCAG AGCTCCTCGTCGTTGTGAATGTCCCTGGAAAGCACGCCGGCCTGCGCGTGCGGAGCGGAG CCCCCCGTGTTCACACACACACAATGGCAAGCATAGTCGCCTGGTTACGGCCCAGGGGGA AGATGCCAAGGGCACCCCTTAATGGAAACACGAGATCAGTAGTGCTATCTCATGACAACC GACGAAGAAACCGACGACAAATCTTTTGGCAGATTTTCTTCTAGTGGCCTTAGAAAACAT GGGCTTTTAAGAAACACGGCTGATATCTTTGAGGGCTGACAAGGCGTCTCTTCAAACAGT TCCATACCAAGTGCTTTGCTCTAGGGAAGCAGTGCGTGTGAAACAGCGTAACGGAGGGTG AAGAGCATAGTTAATAAGCAACTGTAAAAAGTTTTATTTGTTTACTTTAATTCTTTTCCC AGAAGAGTCTTTGATTCACCAAACATGAATGTACATTTTCTAACAAACTCAAAATCTGGG ACCAAAACATCAACTTTTTTCTTTCTTTTTTCTTTCTTTTTGTTTTTTCTTTCCTGTAAA GACCTTGAAAAGCAGTAACTTGGGTCCAGTATTTACGGAGGCGTTGTGAATGTGTCCCAT GCATAACACACTACTGGATAGTGAGTGCTGCGCTAATGTACTACGTAGGGCTTCTACCAG AGATTTTCCTCTCCAATTGGGTTGTGAAATACTCTTCCAAAAGCCTGCATCGGGGATTCC ACCTACTTATTTCAGATTCACCTCCATTAACCAAGAAAACCAGTGGAAGATTTCTTGACT ATTTCACCATGTTGCCAATCAATACTGGAGTAGCAAAAAAAATATTTTCTGGAATACTGT TTTGTAATTCCCTCACTGGGGTGCATTGTAGCTGGAAATTCTCTTTATAAAAATCATTCT TGAGCTCCAGCCTGGCTATCTCTTTCAAGAAACATGGCCACTCTTTAGGAATGCTGTTGC GTTTGCATTGCCAACTAAAATATTAAAATATGCATTGGGGCTTCTTCATTCCTTTATTTT GAGAACCTGATGCACAAAGAGCTCCTTTGTTCTTTTCGAGTCCCACCACTGGAAGAGTGG TCCATAGACCCCATGAAGACATTGTCATGATTTGAGAGACTGTTGTTGAAAGGATTAACA CAATCTTAATACACTGAAAATTTTAACTGTGTCAAGTCAGCTTAGTGGAGATTTAGCTAT GCCAGTGAGCAGTGATTTTAACTATTCTTGGCTGCTTAAACAGGGCAGCTATGAACTATG ACAAATGTAGATTTTTCAAAGCAATACAAAATACTAAAAAAGAGGAACCTTAATGAATAT TAACCACACAGTCTTTCTTAGCCATTCCAAAAAGAGGCAAAGCAATTCTTATTTTCTTTT TTAAAATAATGATTAATATGATTTTGTGCACTTCATACTGTCACTTTTTAAAACTACAGA AAAGAGATTTAGAGTATAACAGAAACAAGTGTGCTTTGATAGTCTCAAATAGGTAGAATT CATAGTTCAAGACCTGAATCCACTGTCATCTCTTTCTTCCTCCCATTGCAGCTATCCTCA GGTACCAAATGTTTTGATTTTTAAATAAGGATAGTAATAAATGGAGGAGGTGTCCTATAA ATTTAAAGTTCAGTTGACCCAGCCTTATACTTAAGATAGCCTTATGAAAAATATGTGCTG TGAGGCAGAAGTATATTTTGGCAGAGAGAATAATAAATAAAACTTTTTCTTTTAGCTCAA TATCCTTACTTTGGTAAGTATTTTTTTTTATTTCACATCTACTTAACAGAAAATAAACTG AGAAATAGAAGTCAGTCCATTGGCATAATTTATCATTCTTCACTTTAAAAAATTCTAATA AATATTCTGCTTGAGTTTTCTTTTCTGCTATTTGTTCTTACTTGCAACTTTAAGTCAAAC CTCCCAATACAAAACATTAAAAGCTAACATTAATGTACTAAAGTATTAATTTAAAAGAAA TCGAACCTCCCATGCTAGATTTGAAAATAACATCATCACAGCACCCTGATCCCAAATATT ACACCGAGGCTTTTAAAATGTAAGTGAAATCTAGCTAAGTTTCATGGTTTCATTAAAAGC AAATGTCTGCCTCTATCTGAAAAACAAATGGAAATCTTTTGAGGTGTTAATACCCTTTGG ATCCTCATCAAAAGGATGGCATTCACCTGAGGATTCCTATCTTGACTTCTTAGGTATTAA AAACCTTTCTTGATATGCTCTACATTTTAAAATTTGTTTTATAAAATCCTTATGTTGATT TTCATTTTATTCTCAAGTACAATACGTTTCACTCTAGACCAGTTGAAGAACATGTTTAAA CTTTGTTCATGGTCAAATTCATTTTCTATTTTTTTAGTAACATATCTCTTAAAAAGCACA CTACCTTATAAAAAACTTCATCAGAAATTAAATTTAATGCAAGTAAATTGCCATCTGATA CTTCCACATGCTATCATAATCAACTGTAATAATAAAAATGATTTATCCAATTAGAAAAGG ACAAGATATATTTTTCTCTGTATTTCTATAACTTTTGCCACTCCATTGAATACATTGTAT GTTGGACATAAGATTATTAGTAATGCATTCTTGAGATCTTTTATTTTGGAATGATGCTAA CTCTGTCTCTTTGCCAATTCTAATACCAGGTTCCAAGTAATAACTCTACAGTACAAAGAG AACTGAATATTCATTCTAGGGCTATAGGATATGAACTTCACAATTCATTTGGGTACATTC TCATTGAATTTCCTTCAAAACAATCTGTTCCTGGTGCCCAGTGATAATTCAGTCGGGACC AGCATGACTAAAAGGAAGGGGATATGCTAAGGCTCAGCAAAGTGACCCTAAATGAGAGAT ATGTCCCAGGATGGAAAGAAGAAGACGTGGTTTAACCAAGTTATACTGACTAATCTAAGC AGTCCACTCATCCTTCCATTTTGGGAAAGGAGTGGGGGCAGCCTAAGAAGAACATATCTG GATTGGGAAGAACCGTCTTTCTGGGCTAGGGATGGGGAACAGAAAGGGAGTATGGAAAGA AAAATTATAAGAGATTTGACTGAAGCAAGGAAAAAAAGCAAATCCCCAAACGTGCTAATC CTTGAAAGTAACTATCTTTCCCAAACTACTGCTGTTACCAGCAAGTGATCAGGAAGACTA GGAGCTATTTCTGACTGTAAATGAATTGTATAATAGCTCTGCTGCAGTTCTGTGACTTCC AAGCCAGGAATTAAATGCTCTTTTTAAGAATAACAAAAAACAAAAGCATTTCCTATGCTA GTCTCCCAGTAAAATGTACATGTTTTGGAGACTTCAAAGGTATTATGTGAGTTCACATTT AGCAACAGCTTATTAATAACCCTCAAGCTGTCAGAATCTCTATAGTTACCATTTACAATT TTATACTGTGAAAAAATACAGATCAGTGAAAGCATAAAGACAAGTCAGAATTCACTTTGA AGAGGGTCTGAGGCCTGGGAGAGTCTCTACTGTCTATTGAAGAATGAGGCATGTATAAAA TAGTTGGTTGAATTTCACTGATCTTCCCAATGTGAACAAATATACTATGTATATTGTGTG TATTTCTAGAAATCAATGGCAGCTGCTGATGGTGTTGTAATTAGAAATCTATATAGATTA TAGATGTTTTAGAAAGATGGTGCCAATCCTAAAAGATTTGTGTGGGCTAAAAGTGCTTGT ACTTACTTTTTTCTGCACTTATAACTGATTTGGTTTTAAAATTGTGTGCGTGTATCTGTT CTTTCTCTGTTGTGGCAGCTTGTACTATTAAAATAATAGAGAATGTTAAATTATTTTGAT GTGAACTGCAAATGATTTTTTTTCATAAAGTTTAACATTTTTATCAGCATTGTTTTGCTT TGTACTTGTATAAATATGTTTTATTTTAGCACTTCAAAATATACTTGCCTGTTTCTCAGT TGTCTAAATCATGTTGTACTTGGTGTTTGTGAAGCCAGTTACTTTTCAAAAAAATTAAAA AACCTATAATATGATTTAAAAAAAAAAAAAAAAAA |
| Restriction Sites | NotI-NotI |
| ACCN | NM_001143831 |
| Insert Size | 3639 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| OTI Annotation | The ORF of this clone has been fully sequenced and found to be a perfect match to NM_001143831.1. |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Reference Data | |
| RefSeq | NM_001143831.1, NP_001137303.1 |
| RefSeq Size | 8062 bp |
| RefSeq ORF | 3639 bp |
| Locus ID | 2915 |
| UniProt ID | P41594 |
| Protein Families | Druggable Genome, GPCR, Transmembrane |
| Protein Pathways | Calcium signaling pathway, Gap junction, Huntington's disease, Long-term depression, Long-term potentiation, Neuroactive ligand-receptor interaction |
| Gene Summary | This gene encodes a member of the G-protein coupled receptor 3 protein family. The encoded protein is a metabatropic glutamate receptor, whose signaling activates a phosphatidylinositol-calcium second messenger system. This protein may be involved in the regulation of neural network activity and synaptic plasticity. Glutamatergic neurotransmission is involved in most aspects of normal brain function and can be perturbed in many neuropathologic conditions. A pseudogene of this gene has been defined on chromosome 11. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2014] Transcript Variant: This variant (a) encodes the longer isoform (a, also known as mGluR5b). Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. |
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Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC227736 | GRM5 (Myc-DDK-tagged)-Human glutamate receptor, metabotropic 5 (GRM5), transcript variant a |
CNY 8,440.00 |
|
| RC227736L1 | Lenti-ORF clone of GRM5 (Myc-DDK-tagged)-Human glutamate receptor, metabotropic 5 (GRM5), transcript variant a |
CNY 10,840.00 |
|
| RC227736L2 | Lenti-ORF clone of GRM5 (mGFP-tagged)-Human glutamate receptor, metabotropic 5 (GRM5), transcript variant a |
CNY 11,500.00 |
|
| RC227736L3 | Lenti-ORF clone of GRM5 (Myc-DDK-tagged)-Human glutamate receptor, metabotropic 5 (GRM5), transcript variant a |
CNY 11,500.00 |
|
| RC227736L4 | Lenti-ORF clone of GRM5 (mGFP-tagged)-Human glutamate receptor, metabotropic 5 (GRM5), transcript variant a |
CNY 10,840.00 |
|
| RG227736 | GRM5 (tGFP-tagged) - Human glutamate receptor, metabotropic 5 (GRM5), transcript variant a |
CNY 10,040.00 |
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