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KPNA2 (NM_002266) Human Untagged Clone
CAT＃: SC321886
KPNA2 (untagged)-Human karyopherin alpha 2 (RAG cohort 1, importin alpha 1) (KPNA2)
CNY 2,950.00
| Cited in 1 publication. |
Product images
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | IPOA1; QIP2; RCH1; SRP1-alpha; SRP1alpha |
| Vector | pCMV6-AC |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | Neomycin |
| Sequence Data |
>OriGene sequence for NM_002266.2
GAGCTGAGTCGAGGTGGACCCTTTGAACGCAGTCGCCCTACAGCCGCTGATTCCCCCCGC
ATCGCCTCCCGTGGAAGCCCAGGCCCGCTTCGCAGCTTTCTCCCTTTGTCTCATAACCAT GTCCACCAACGAGAATGCTAATACACCAGCTGCCCGTCTTCACAGATTCAAGAACAAGGG AAAAGACAGTACAGAAATGAGGCGTCGCAGAATAGAGGTCAATGTGGAGCTGAGGAAAGC TAAGAAGGATGACCAGATGCTGAAGAGGAGAAATGTAAGCTCATTTCCTGATGATGCTAC TTCTCCGCTGCAGGAAAACCGCAACAACCAGGGCACTGTAAATTGGTCTGTTGATGACAT TGTCAAAGGCATAAATAGCAGCAATGTGGAAAATCAGCTCCAAGCTACTCAAGCTGCCAG GAAACTACTTTCCAGAGAAAAACAGCCCCCCATAGACAACATAATCCGGGCTGGTTTGAT TCCGAAATTTGTGTCCTTCTTGGGCAGAACTGATTGTAGTCCCATTCAGTTTGAATCTGC TTGGGCACTCACTAACATTGCTTCTGGGACATCAGAACAAACCAAGGCTGTGGTAGATGG AGGTGCCATCCCAGCATTCATTTCTCTGTTGGCATCTCCCCATGCTCACATCAGTGAACA AGCTGTCTGGGCTCTAGGAAACATTGCAGGTGATGGCTCAGTGTTCCGAGACTTGGTTAT TAAGTACGGTGCAGTTGACCCACTGTTGGCTCTCCTTGCAGTTCCTGAGATGTCATCTTT AGCATGTGGCTACTTACGTAATCTTACCTGGACACTTTCTAATCTTTGCCGCAACAAGAA TCCTGCACCCCCGATAGATGCTGTTGAGCAGATTCTTCCTACCTTAGTTCGGCTCCTGCA TCATGATGATCCAGAAGTGTTAGCAGATACCTGCTGGGCTATTTCCTACCTTACTGATGG TCCAAATGAACGAATTGGCATGGTGGTGAAAACAGGAGTTGTGCCCCAACTTGTGAAGCT TCTAGGAGCTTCTGAATTGCCAATTGTGACTCCTGCCCTAAGAGCCATAGGGAATATTGT CACTGGTACAGATGAACAGACTCAGGTTGTGATTGATGCAGGAGCACTCGCCGTCTTTCC CAGCCTGCTCACCAACCCCAAAACTAACATTCAGAAGGAAGCTACGTGGACAATGTCAAA CATCACAGCCGGCCGCCAGGACCAGATACAGCAAGTTGTGAATCATGGATTAGTCCCATT CCTTGTCAGTGTTCTCTCTAAGGCAGATTTTAAGACACAAAAGGAAGCTGTGTGGGCCGT GACCAACTATACCAGTGGTGGAACAGTTGAACAGATTGTGTACCTTGTTCACTGTGGCAT AATAGAACCGTTGATGAACCTCTTAACTGCAAAAGATACCAAGATTATTCTGGTTATCCT GGATGCCATTTCAAATATCTTTCAGGCTGCTGAGAAACTAGGTGAAACTGAGAAACTTAG TATAATGATTGAAGAATGTGGAGGCTTAGACAAAATTGAAGCTCTACAAAACCATGAAAA TGAGTCTGTGTATAAGGCTTCGTTAAGCTTAATTGAGAAGTATTTCTCTGTAGAGGAAGA GGAAGATCAAAACGTTGTACCAGAAACTACCTCTGAAGGCTACACTTTCCAAGTTCAGGA TGGGGCTCCTGGGACCTTTAACTTTTAGATCATGTAGCTGAGACATAAATTTGTTGTGTA CTACGTTTGGTATTTTGTCTTATTGTTTCTCTACTAAGAACTCTTTCTTAAATGTGGTTT GTTACTGTAGCACTTTTTACACTGAAACTATACTTGAACAGTTCCAACTGTACATACATA CTGTATGAAGCTTGTCCTCTGACTAGGTTTCTAATTTCTATGTGGAATTTCCTATCTTGC AGCATCCTGTAAATAAACATTCAAGTCCACCCTTTTCTTGACTTCAAAAAAAAAAAAAAA AAAAAAAAAAAAAAAAA |
| Restriction Sites | Please inquire |
| ACCN | NM_002266 |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| OTI Annotation | This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA. |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Reference Data | |
| RefSeq | NM_002266.2, NP_002257.1 |
| RefSeq Size | 2011 bp |
| RefSeq ORF | 1590 bp |
| Locus ID | 3838 |
| UniProt ID | P52292 |
| Domains | Armadillo_seg, IBB |
| Protein Families | Druggable Genome, Stem cell - Pluripotency |
| Gene Summary | The import of proteins into the nucleus is a process that involves at least 2 steps. The first is an energy-independent docking of the protein to the nuclear envelope and the second is an energy-dependent translocation through the nuclear pore complex. Imported proteins require a nuclear localization sequence (NLS) which generally consists of a short region of basic amino acids or 2 such regions spaced about 10 amino acids apart. Proteins involved in the first step of nuclear import have been identified in different systems. These include the Xenopus protein importin and its yeast homolog, SRP1 (a suppressor of certain temperature-sensitive mutations of RNA polymerase I in Saccharomyces cerevisiae), which bind to the NLS. KPNA2 protein interacts with the NLSs of DNA helicase Q1 and SV40 T antigen and may be involved in the nuclear transport of proteins. KPNA2 also may play a role in V(D)J recombination. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2016] Transcript Variant: This variant (2) differs in the 5' UTR compared to variant 1. Both variants 1 and 2 encode the same protein. |
Citations (1)
| The use of this cDNA Clones has been cited in the following citations: |
|---|
|
Tyrosine 132 Phosphorylation of Influenza A Virus M1 Protein Is Crucial for Virus Replication by Controlling the Nuclear Import of M1
,Shanshan Wang, Zhendong Zhao, Yuhai Bi, Lei Sun, Xiaoling Liu, and Wenjun Liu,
J. Virol., Jun 2013; 87: 6182 - 6191.
,PubMed ID 23536660
[KPNA2]
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Documents
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Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC208803 | KPNA2 (Myc-DDK-tagged)-Human karyopherin alpha 2 (RAG cohort 1, importin alpha 1) (KPNA2) |
CNY 3,936.00 |
|
| RC208803L1 | Lenti ORF clone of Human karyopherin alpha 2 (RAG cohort 1, importin alpha 1) (KPNA2), Myc-DDK-tagged |
CNY 5,890.00 |
|
| RC208803L2 | Lenti ORF clone of Human karyopherin alpha 2 (RAG cohort 1, importin alpha 1) (KPNA2), mGFP tagged |
CNY 5,890.00 |
|
| RC208803L3 | Lenti ORF clone of Human karyopherin alpha 2 (RAG cohort 1, importin alpha 1) (KPNA2), Myc-DDK-tagged |
CNY 6,336.00 |
|
| RC208803L4 | Lenti ORF clone of Human karyopherin alpha 2 (RAG cohort 1, importin alpha 1) (KPNA2), mGFP tagged |
CNY 5,890.00 |
|
| RG208803 | KPNA2 (tGFP-tagged) - Human karyopherin alpha 2 (RAG cohort 1, importin alpha 1) (KPNA2) |
CNY 4,370.00 |
