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AMPK gamma 1 (PRKAG1) (NM_002733) Human Untagged Clone
CAT＃: SC321552
PRKAG1 (untagged)-Human protein kinase, AMP-activated, gamma 1 non-catalytic subunit (PRKAG1), transcript variant 1
CNY 2,400.00
CNY 2,950.00
| Cited in 1 publication. |
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热销推荐Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | AMPKG |
| Vector | pCMV6-AC |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | Neomycin |
| Sequence Data |
>OriGene sequence for NM_002733.3
GCGAGGAAACCAAGCCGGGCGCCTCTTGCAATGGAGACGGTCATTTCTTCAGATAGCTCC
CCAGCTGTGGAAAATGAGCATCCTCAAGAGACCCCAGAATCCAACAATAGCGTGTATACT TCCTTCATGAAGTCTCATCGCTGCTATGACCTGATTCCCACAAGCTCCAAATTGGTTGTA TTTGATACGTCCCTGCAGGTGAAGAAAGCTTTTTTTGCTTTGGTGACTAACGGTGTACGA GCTGCCCCTTTATGGGATAGTAAGAAGCAAAGTTTTGTGGGCATGCTGACCATCACTGAT TTCATCAATATCCTGCACCGCTACTATAAATCAGCCTTGGTACAGATCTATGAGCTAGAA GAACACAAGATAGAAACTTGGAGAGAGGTGTATCTCCAGGACTCCTTTAAACCGCTTGTC TGCATTTCTCCTAATGCCAGCTTGTTTGATGCTGTCTCTTCATTAATTCGGAACAAGATC CACAGGCTGCCAGTTATTGACCCAGAATCAGGCAATACTTTGTACATCCTCACCCACAAG CGCATTCTGAAGTTCCTCAAATTGTTTATCACTGAGTTCCCCAAGCCAGAGTTCATGTCC AAGTCTCTGGAAGAGCTACAGATTGGCACCTATGCCAATATTGCTATGGTTCGCACTACC ACCCCCGTCTATGTGGCTCTGGGGATTTTTGTACAGCATCGAGTCTCAGCCCTGCCAGTG GTGGATGAGAAGGGGCGTGTGGTGGACATCTACTCCAAGTTTGATGTTATCAATCTGGCA GCAGAAAAGACCTACAACAACCTAGATGTATCTGTGACTAAAGCCTTGCAACATCGATCA CATTACTTTGAGGGTGTTCTCAAGTGCTACCTGCATGAGACTCTGGAGACCATCATCAAC AGGCTAGTGGAAGCAGAGGTTCACCGACTTGTAGTGGTGGATGAAAATGATGTGGTCAAG GGAATTGTATCACTGTCTGACATCCTGCAGGCCCTGGTGCTCACAGGTGGAGAGAAGAAG CCCTGAGCTGGGGGAAGGGGTCATGCAGCACCAGGGGATATGCCCAACTCACTGCCTGCT GGAAGCTCTGTGGGAATCAGATGAAACTTGAGGGAATTGTGACTCTGTTCCCTGTTCAGG GTCCCCTGCCCTTCTATCTGGGAGCTAGGGAAGGTATGGGGGAGGAAAGAGAATGGATTT ATAGCTACCCTTACCCTCACACATACACTTGAAAAAACTTTCAGCCTAGCCAGTTCTAGC CCCTGTCCTCTTAGATATATCCCCCTTTCTGGGTGAACTATAGGCTCTGTGCCTCTCAGA CAAATTCTGATCTCTAAGAGATCCCCAGACCTCACTTGCCTCTGCCTCCATCTTGGCCCT GATTCAACCCTAAGATAATAGCACAACAAAATTCTTCATAAAGATATTTTTATTCACCTG TTCCGTGCTATATGGAGGAGGCCAAGTCCATTTAGTGACATTTCTTCCCATAATGTGAGT GGGGAGGATTGTGGGGAGGAGGGGCTTTGGGTTCCTGTGTTTGTGCATATGAAGGGAGAT GGGGGTTAGGTGGAGGAGGAGAGCAGCGTGGTTAGCTAAGGTTATTGCTTTTTGTGGCAA ATCTAATTAAATGACAGGAATCTCAAAAAAAAAAAAAAAAAAAAAAAA |
| Restriction Sites | Please inquire |
| ACCN | NM_002733 |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| OTI Annotation | This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA. |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Reference Data | |
| RefSeq | NM_002733.3, NP_002724.1 |
| RefSeq Size | 1707 bp |
| RefSeq ORF | 996 bp |
| Locus ID | 5571 |
| UniProt ID | P54619 |
| Domains | CBS |
| Protein Families | Druggable Genome |
| Protein Pathways | Adipocytokine signaling pathway, Hypertrophic cardiomyopathy (HCM), Insulin signaling pathway |
| Gene Summary | The protein encoded by this gene is a regulatory subunit of the AMP-activated protein kinase (AMPK). AMPK is a heterotrimer consisting of an alpha catalytic subunit, and non-catalytic beta and gamma subunits. AMPK is an important energy-sensing enzyme that monitors cellular energy status. In response to cellular metabolic stresses, AMPK is activated, and thus phosphorylates and inactivates acetyl-CoA carboxylase (ACC) and beta-hydroxy beta-methylglutaryl-CoA reductase (HMGCR), key enzymes involved in regulating de novo biosynthesis of fatty acid and cholesterol. This subunit is one of the gamma regulatory subunits of AMPK. Alternatively spliced transcript variants encoding distinct isoforms have been observed. [provided by RefSeq, Jul 2008] Transcript Variant: This variant (1) encodes isoform 1. |
Citations (1)
| The use of this cDNA Clones has been cited in the following citations: |
|---|
|
The energy sensor AMP-activated protein kinase directly regulates the mammalian FOXO3 transcription factor
,Eric L Greer, Philip R Oskoui, Max R Banko, Jay M Maniar, Melanie P Gygi, Steven P Gygi, and Anne Brunet,
J Biol Chem. 2007 Oct 12;282(41):30107-19.
[PRKAG1]
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Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC201845 | PRKAG1 (Myc-DDK-tagged)-Human protein kinase, AMP-activated, gamma 1 non-catalytic subunit (PRKAG1), transcript variant 1 |
CNY 2,400.00 |
|
| RC201845L1 | Lenti ORF clone of Human protein kinase, AMP-activated, gamma 1 non-catalytic subunit (PRKAG1), transcript variant 1, Myc-DDK-tagged |
CNY 4,800.00 |
|
| RC201845L2 | Lenti ORF clone of Human protein kinase, AMP-activated, gamma 1 non-catalytic subunit (PRKAG1), transcript variant 1, mGFP tagged |
CNY 5,890.00 |
|
| RC201845L3 | Lenti ORF clone of Human protein kinase, AMP-activated, gamma 1 non-catalytic subunit (PRKAG1), transcript variant 1, Myc-DDK-tagged |
CNY 4,800.00 |
|
| RC201845L4 | Lenti ORF clone of Human protein kinase, AMP-activated, gamma 1 non-catalytic subunit (PRKAG1), transcript variant 1, mGFP tagged |
CNY 4,800.00 |
|
| RG201845 | PRKAG1 (tGFP-tagged) - Human protein kinase, AMP-activated, gamma 1 non-catalytic subunit (PRKAG1), transcript variant 1 |
CNY 4,000.00 |
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