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Beta Arrestin 2 (ARRB2) (NM_199004) Human Untagged Clone
CAT＃: SC307849
ARRB2 (untagged)-Human arrestin, beta 2 (ARRB2), transcript variant 2
CNY 3,656.00
CNY 6,370.00
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热销推荐Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | ARB2; ARR2; BARR2 |
| Vector | pCMV6-XL5 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data |
>OriGene sequence for NM_199004 edited
GAATTCGGCACGAGGGGCGCGCGCACCATGGGGGAGAAACCCGGGACCAGGGTCTTCAAG AAGTCGAGCCCTAACTGCAAGCTCACCGTGTACTTGGGCAAGCGGGACTTCGTAGATCAC CTGGACAAAGTGGACCCTGTAGTGTTTGTGACCCTCACCTGCGCCTTCCGCTATGGCCGT GAAGACCTGGATGTGCTGGGCTTGTCCTTCCGCAAAGACCTGTTCATCGCCACCTACCAG GCCTTCCCCCCGGTGCCCAACCCACCCCGGCCCCCCACCCGCCTGCAGGACCGGCTGCTG AGGAAGCTGGGCCAGCATGCCCACCCCTTCTTCTTCACCATACCCCAGAATCTTCCATGC TCCGTCACACTGCAGCCAGGCCCAGAGGATACAGGAAAGGCCTGCGGCGTAGACTTTGAG ATTCGAGCCTTCTGTGCTAAATCACTAGAAGAGAAAAGCCACAAAAGGAACTCTGTGCGG CTGGTGATCCGAAAGGTGCAGTTCGCCCCGGAGAAACCCGGCCCCCAGCCTTCAGCCGAA ACCACACGCCACTTCCTCATGTCTGACCGGTCCCTGCACCTCGAGGCTTCCCTGGACAAG GAGCTGTACTACCATGGGGAGCCCCTCAATGTAAATGTCCACGTCACCAACAACTCCACC AAGACCGTCAAGAAGATCAAAGTCTCTGTGAGACAGTACGCCGACATCTGCCTCTTCAGC ACCGCCCAGTACAAGTGTCCTGTGGCTCAACTCGAACAAGATGACCAGGTATCTCCCAGC TCCACATTCTGTAAGGTGTACACCATAACCCCACTGCTCAGTGACAACCGGGAGAAGCGG GGTCTCGCCCTGGATGGGAAACTCAAGCACGAGGACACCAACCTGGCTTCCAGCACCATC GTGAAGGAGGGTGCCAACAAGGAGGTGCTGGGAATCCTGGTGTCCTACAGGGTCAAGGTG AAGCTGGTGGTGTCTCGAGGCGGGGATGTCTCTGTGGAGCTGCCTTTTGTTCTTATGCAC CCCAAGCCCCACGACCACATCCCCCTCCCCAGACCCCAGTCAGCCGCTCCGGAGACAGAT GTCCCTGTGGACACCAACCTCATTGAATTTGATACCAACTATGCCACAGATGATGACATT GTGTTTGAGGACTTTGCCCGGCTTCGGCTGAAGGGGATGAAGGATGACGACTATGATGAT CAACTCTGCTAGGAAGCGGGGTGGGAAGAAGGGAGGGGATGGGGTTGGGAGAGGTGAGGG CAGGATTAAGATCCCCACTGTCAATGGGGGATTGTCCCAGCCCCTCTTCCCTTCCCCTCA CCTGGAAGCTTCTTCAACCAATCCCTTCACACTCTCTCCCCCATCCCCCCAAGATACACA CTGGACCCTCTCTTGCTGAATGTGGGCATTAATTTTTTGACTGCAGCTCTGCTTCTCCAG CCCCGCCGTGGGTGGCAAGCTGTGTTCATACCTAAATTTTCTGGAAGGGGACAGTGAAAA GAGGAGTGACAGGAGGGAAAGGGGGAGACAAAACTCCTACTCTCAACCTCACACCAACAC CTCCCATTATCACTCTCTCTGCCCCCATTCCTTCAAGAGGAGACCCTTTGGGGACAAGGC CGTTTCTTTGTTTCTGAGCATAAAGAAGAAAATAAATCTTTTACTAAGAAAAAAAAAAAA AAAAAA |
| Restriction Sites | NotI-NotI |
| ACCN | NM_199004 |
| Insert Size | 1930 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| OTI Annotation | This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA. |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Reference Data | |
| RefSeq | NM_199004.1, NP_945355.1 |
| RefSeq Size | 1891 bp |
| RefSeq ORF | 1185 bp |
| Locus ID | 409 |
| UniProt ID | P32121 |
| Protein Families | Druggable Genome |
| Protein Pathways | Chemokine signaling pathway, Endocytosis, MAPK signaling pathway, Olfactory transduction |
| Gene Summary | Members of arrestin/beta-arrestin protein family are thought to participate in agonist-mediated desensitization of G-protein-coupled receptors and cause specific dampening of cellular responses to stimuli such as hormones, neurotransmitters, or sensory signals. Arrestin beta 2, like arrestin beta 1, was shown to inhibit beta-adrenergic receptor function in vitro. It is expressed at high levels in the central nervous system and may play a role in the regulation of synaptic receptors. Besides the brain, a cDNA for arrestin beta 2 was isolated from thyroid gland, and thus it may also be involved in hormone-specific desensitization of TSH receptors. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2012] Transcript Variant: This variant (2) lacks an alternate in-frame exon and uses an alternate in-frame splice junction at the 3' end of another exon compared to variant 3. The resulting isoform (2) lacks two alternate internal segments compared to isoform 3. |
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Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC212960 | ARRB2 (Myc-DDK-tagged)-Human arrestin, beta 2 (ARRB2), transcript variant 2 |
CNY 3,656.00 |
|
| RC212960L1 | Lenti ORF clone of Human arrestin, beta 2 (ARRB2), transcript variant 2, Myc-DDK-tagged |
CNY 5,890.00 |
|
| RC212960L2 | Lenti ORF clone of Human arrestin, beta 2 (ARRB2), transcript variant 2, mGFP tagged |
CNY 5,890.00 |
|
| RC212960L3 | Lenti ORF clone of Human arrestin, beta 2 (ARRB2), transcript variant 2, Myc-DDK-tagged |
CNY 5,890.00 |
|
| RC212960L4 | Lenti ORF clone of Human arrestin, beta 2 (ARRB2), transcript variant 2, mGFP tagged |
CNY 5,890.00 |
|
| RG212960 | ARRB2 (tGFP-tagged) - Human arrestin, beta 2 (ARRB2), transcript variant 2 |
CNY 4,370.00 |
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