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CD42d (GP5) (NM_004488) Human Untagged Clone
CAT＃: SC303489
GP5 (untagged)-Human glycoprotein V (platelet) (GP5)
CNY 6,680.00
Product images
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | CD42d; GPV |
| Vector | pCMV6-Entry |
| E. coli Selection | Kanamycin (25 ug/mL) |
| Mammalian Cell Selection | Neomycin |
| Sequence Data |
>SC303489 representing NM_004488.
Blue=Insert sequence Red=Cloning site Green=Tag(s) GCTCGTTTAGTGAACCGTCAGAATTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTG GATCCGGTACCGAGGAGATCTGCCGCCGCGATCGCC ATGCTGAGGGGGACTCTACTGTGCGCGGTGCTCGGGCTTCTGCGCGCCCAGCCCTTCCCCTGTCCGCCA GCTTGCAAGTGTGTCTTCCGGGACGCCGCGCAGTGCTCGGGGGGCGACGTGGCGCGCATCTCCGCGCTA GGCCTGCCCACCAACCTCACGCACATCCTGCTCTTCGGAATGGGCCGCGGCGTCCTGCAGAGCCAGAGC TTCAGCGGCATGACCGTCCTGCAGCGCCTCATGATCTCCGACAGCCACATTTCCGCCGTTGCCCCCGGC ACCTTCAGTGACCTGATAAAACTGAAAACCCTGAGGCTGTCGCGCAACAAAATCACGCATCTTCCAGGT GCGCTGCTGGATAAGATGGTGCTCCTGGAGCAGTTGTTTTTGGACCACAATGCGCTAAGGGGCATTGAC CAAAACATGTTTCAGAAACTGGTTAACCTGCAGGAGCTCGCTCTGAACCAGAATCAGCTCGATTTCCTT CCTGCCAGTCTCTTCACGAATCTGGAGAACCTGAAGTTGTTGGATTTATCGGGAAACAACCTGACCCAC CTGCCCAAGGGGTTGCTTGGAGCACAGGCTAAGCTCGAGAGACTTCTGCTCCACTCGAACCGCCTTGTG TCTCTGGATTCGGGGCTGTTGAACAGCCTGGGCGCCCTGACGGAGCTGCAGTTCCACCGAAATCACATC CGTTCCATCGCACCCGGGGCCTTCGACCGGCTCCCAAACCTCAGTTCTTTGACGCTTTCGAGAAACCAC CTTGCGTTTCTCCCCTCTGCGCTCTTTCTTCATTCGCACAATCTGACTCTGTTGACTCTGTTCGAGAAC CCGCTGGCAGAGCTCCCGGGGGTGCTCTTCGGGGAGATGGGGGGCCTGCAGGAGCTGTGGCTGAACCGC ACCCAGCTGCGCACCCTGCCCGCCGCCGCCTTCCGCAACCTGAGCCGCCTGCGGTACTTAGGGGTGACT CTGAGCCCGCGGCTGAGCGCGCTTCCGCAGGGCGCCTTCCAGGGCCTTGGCGAGCTCCAGGTGCTCGCC CTGCACTCCAACGGCCTGACCGCCCTCCCCGACGGCTTGCTGCGCGGCCTCGGCAAGCTGCGCCAGGTG TCCCTGCGCCGCAACAGGCTGCGCGCCCTGCCCCGTGCCCTCTTCCGCAATCTCAGCAGCCTGGAGAGC GTCCAGCTCGACCACAACCAGCTGGAGACCCTGCCTGGCGACGTGTTTGGGGCTCTGCCCCGGCTGACG GAGGTCCTGTTGGGGCACAACTCCTGGCGCTGCGACTGTGGCCTGGGGCCCTTCCTGGGGTGGCTGCGG CAGCACCTAGGCCTCGTGGGCGGGGAAGAGCCCCCACGGTGCGCAGGCCCTGGGGCGCACGCCGGCCTG CCGCTCTGGGCCCTGCCGGGGGGTGACGCGGAGTGCCCGGGCCCCCGGGGCCCGCCTCCCCGCCCCGCT GCGGACAGCTCCTCGGAAGCCCCTGTCCACCCAGCCTTGGCTCCCAACAGCTCAGAACCCTGGGTGTGG GCCCAGCCGGTGACCACGGGCAAAGGTCAAGATCATAGTCCGTTCTGGGGGTTTTATTTTCTGCTTTTA GCTGTTCAGGCCATGATCACCGTGATCATCGTGTTTGCTATGATTAAAATTGGCCAACTCTTTCGAAAA TTAATCAGAGAGAGAGCCCTTGGGTAA ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGAT TACAAGGATGACGACGATAAGGTTTAAACGGCCGGC |
| Restriction Sites | SgfI-MluI |
| ACCN | NM_004488 |
| Insert Size | 1683 bp |
| OTI Disclaimer | Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at custsupport@origene.com or by calling 301.340.3188 option 3 for pricing and delivery. The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| OTI Annotation | This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA. |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Reference Data | |
| RefSeq | NM_004488.2 |
| RefSeq Size | 3493 bp |
| RefSeq ORF | 1683 bp |
| Locus ID | 2814 |
| UniProt ID | P40197 |
| Protein Families | Druggable Genome, Transmembrane |
| Protein Pathways | ECM-receptor interaction, Hematopoietic cell lineage |
| MW | 61 kDa |
| Gene Summary | Human platelet glycoprotein V (GP5) is a part of the Ib-V-IX system of surface glycoproteins that constitute the receptor for von Willebrand factor (VWF; MIM 613160) and mediate the adhesion of platelets to injured vascular surfaces in the arterial circulation, a critical initiating event in hemostasis. The main portion of the receptor is a heterodimer composed of 2 polypeptide chains, an alpha chain (GP1BA; MIM 606672) and a beta chain (GP1BB; MIM 138720), that are linked by disulfide bonds. The complete receptor complex includes noncovalent association of the alpha and beta subunits with platelet glycoprotein IX (GP9; MIM 173515) and GP5. Mutations in GP1BA, GP1BB, and GP9 have been shown to cause Bernard-Soulier syndrome (MIM 231200), a bleeding disorder (review by Lopez et al., 1998 [PubMed 9616133]).[supplied by OMIM, Nov 2010] |
Documents
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Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC218870 | GP5 (Myc-DDK-tagged)-Human glycoprotein V (platelet) (GP5) |
CNY 6,256.00 |
|
| RC218870L3 | Lenti ORF clone of Human glycoprotein V (platelet) (GP5), Myc-DDK-tagged |
CNY 6,840.00 |
|
| RC218870L4 | Lenti ORF clone of Human glycoprotein V (platelet) (GP5), mGFP tagged |
CNY 6,840.00 |
|
| RG218870 | GP5 (tGFP-tagged) - Human glycoprotein V (platelet) (GP5) |
CNY 5,420.00 |
