PAQR6 (AK095143) Human Untagged Clone

Specifications

Product Data
Type	Human Untagged Clone
Tag	Tag Free
Synonyms	PRdelta
Vector	pCMV6-XL5
E. coli Selection	Ampicillin (100 ug/mL)
Mammalian Cell Selection	None
Sequence Data	Fully Sequenced ORF (showhide) >NCBI ORF sequence for AK095143, the custom clone sequence may differ by one or more nucleotides ATGTCGCCCCGCATGCGCCACATCTGCTACTTCCTCGACTACGGCGCGCTCAGCCTCTACAGTCTGGGCT GCGCCTTCCCCTATGCCGCCTACTCCATGCCGGCCTCCTGGCTGCACGGCCACCTGCACCAGTTCTTTGT GCCTGCCGCCGCACTCAACTCCTTCCTGTGCACCGGCCTCTCCTGCTACTCCCGTTTCCTGGAGCTGGAA AGCCCTGGGCTCAGTAAGGTCCTCCGCACAGGAGCCTTCGCCTATCCATTCCTGTTCGACAACCTCCCAC TCTTTTATCGGCTCGGGCTGTGCTGGGGCAGGGGCCACGGCTGTGGGCAGGAGGCCCTGAGCACCAGCCA TGGCTACCATCTCTTCTGCGCGCTGCTCACTGGCTTCCTCTTCGCCTCCCACCTGCCTGAAAGGCTGGCA CCAGGACGCTTTGATTACATCGGTGAGGGCACGCCTGGCCCGGCCCGGGAAGAGGCAGGGGCAGATGCCT TCCCAGAGCACAGAATGAACTGGGCCACAGCCACCAGTTATTCCACATCTGTGCAGTGCTGGGCACCCAC TTCCAGCTGGAGGCAGTGCTGGCTGATATGGGATCACGCAGAGCCTGGCTGGCCACACAGGAACCTGCCC TGGGCCTGGCAGGCACAGTGGCCACACTGGTCTTGGCTGCAGCTGGGAACCTACTCATTATTGCTGCTTT CACAGCCACCCTGCTTCGGGCCCCCAGTACATGCCCTCTGCTGCAGGGTGGCCCACTGGAGGGGGGTACC CAGGCCAAACAACAGTGAGGCCCCATCCCTGACCCTGTCCTGGAGGGGGCAGAGGCCAGGCCCCAGTGCT GACGAGGAGCCCAGATTTGGGCCTAATCAGGTGGGGACGCATCTCAGCCTGGAACCAACAGGGGCTGAGG AGAGAGGGCACAGGAGAGAGGGCAGAGAAGAGGAGGGGTGTCTAGGGGGACTGGCAGAGTGTGAGAGGGA CCGTGAGGGGGCTCTTGATGGGAGTGGAAGAAGTGCTGAGGGTCTGAGAGGGGAGATGCATGCGTGTCCA GGCTGA 5' Read Nucleotide Sequence (showhide) >OriGene 5' read for AK095143 unedited GCAAATTTGTATACGACTACTATAGGGCGGCCGCGATTCGGCACGAGGCCTCGTGCCGAA TTCGGCACGAGGCTGCTGCCCGCCTGCCTCTACCCCTTCGCGTCGTGCTGCGCGCACACC TTCAGCTCCATGTCGCCCCGCATGCGCCACATCTGCTACTTCCTCGACTACGGCGCGCTC AGCCTCTACAGTCTGGTTTCCTGGAGCTGGAAAGCCCTGGGCTCAGTAAGGTCCTCCGCA CAGGAGCCTTCGCCTATCCATTCCTGTTCGACAACCTCCCACTCTTTTATCGGCTCGGGC TGTGCTGGGGCAGGGGCCACGGCTGTGGGCAGGAGGCCCTGAGCACCAGCCATGGCTACC ATCTCTTCTGCGCGCTGCTCACTGGCTTCCTCTTCGCCTCCCACCTGCCTGAAAGGCTGG CACCAGGACGCTTTGATTACATCGGCCACAGCCACCAGTTATTCCACATCTGTGCAGTGC TGGGCACCCACTTCCAGCTGGAGGCAGTGCTGGCTGATATGGGATCACGCAGAGCCTGGC TGGCCACACAGGAACCTGCCCTGNGCCTGGCAGGCACAGTGGCCACACTGGTCTTGGCTG CAGCTGNGAACCTACTCATTATTGCTGCTTTCACAGCCACCCTGCTTCGGGCCCCCAGTA CATGCCCTCTGCTGCAGGGTGGCCCACTGGANGGGGGGTACCCAGGCCAAACAACAGTGA GGCCCCATCCCTGACCCTGTCCTGGNAGGGGCAGAGGCCCAGCCCCAGTGCTGACGAGGA GCCCAGATTTGGGCCTAATTCAGTGGGGACGCATCTCAGCCTGGAACCCACAGGGCTGNA GAGAGAGGCCACAGANANAGGCANANANNAGAGGGTGTCTAGGGGACTGCCNATGTGAAA GGACCGGAGG 3' Read Nucleotide Sequence (showhide) >OriGene 3' read for AK095143 unedited GCACGCAATCTATAGTCGAGTTTTTTTTTTTTTTTTTTGCTTTCCAAATTTTATTTTTTT ATTTGTACCTGCCTTGTTCCAGAAAACATTGAAGGGGGCTTCCCAAAGTCTAACTAGGGA TACCCCCTCTAGCCTAGGACCCTCCTCCCCACACCTCAATCCACCAAACCATCCATAATG CACCCAGATAGGCCCACCCCCAAAAGCCTGGACACCTTGAGCACACAGTTATGACCAGGA CAGACTCATCTCTATAGGCAAATAGCTGCTGGCAAACTGGCATTACCTGGTTTGTGGGGA TGGGGGGGCAAGTGTGTGGCCTCTCGGCCTGGTTAGCAAGAAGCATTCAGGGTAGGCCTA GGTTAGTCGTGTTAGTTCTTCCCTGTGCTGAGCAGAGACTTCCAGAAGCACCAGAAACGG AGCCAGATGAAAGGACCCCAACACCTCCCCCCGCCAACCTTTGACAGAATATAGGGGCAT CTTCAGCCTGGACACGCATGCATCTCCCCTCTCAGACCCTCAGCACTTCTTCCACTCCCA TCAAGAGCCCCCTCACGGTCCCTCTCACACTCTGCCAGTCCCCCTAGACACCCCTCCTCT TCTCTGCCCTCTCTCCTGTGCCCTCTCTCCTCAGCCCCTGTTGGTTCCAGGCTGAGATGC GTCCCCACCTGATTAGGCCCAAATCTGGGCTCCTCGTCAGCACTGGGGCCTGGCCTCTGC CCCCTNNCAGAAGGGTCAAGGATGGGGCCTCACTGTTGTTTGGCCTGAGTACCCCCCTCA GTGGGCCCACCTGCANAGAAGGCATGTACTGTNGGCCCGAACCAGGTGGCTGTGAAACAC CATTATGAGGTAGTTCCCAGCTGAGCCAAGACAGTGTGCCACTGTGCCTGCCAGCCCCAA GCAGTNCCTGTGTGGACAGCAGCTCTGGNTGATCCCTATNACCANCCTGGCTCAACTGAA TTGGGTGCCANACTGGACT
Restriction Sites	NotI-NotI
ACCN	AK095143
Insert Size	1470 bp
OTI Disclaimer	The sequence of an 'OriGene Unique Variant' differs significantly from the associated reference. It represents a novel splice variant from the same gene locus of the reference. Although such variants are true transcripts and present opportunity for discoveries, they are not yet curated by NCBI and should not be used if the exact reference accession sequence is required.
OTI Annotation	This TrueClone was found to represent an alternative form of the specific reference to which it is associated. Its Open Reading Frame (ORF) may represent a novel form or alternative splice variant. By virtue of it being a true transcript (cDNA clone not PCR product), it provides a biologically relevant copy of its mRNA template. For more details, please evaluate the sequence information provided on this website or contact our customer care specialists.
Product Components	The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
Reconstitution	1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.
Reference Data
RefSeq	AK095143.1, BAC04493.1
RefSeq Size	1906 bp
RefSeq ORF	1056 bp
Locus ID	79957
Protein Families	Druggable Genome, Transmembrane
Gene Summary	Plasma membrane progesterone (P4) receptor coupled to G proteins (PubMed:23763432, PubMed:23161870). Seems to act through a G(s) mediated pathway (PubMed:23161870). Involved in neurosteroid inhibition of apoptosis (PubMed:23161870). May be involved in regulating rapid P4 signaling in the nervous system (PubMed:23763432). Also binds dehydroepiandrosterone (DHEA), pregnanolone, pregnenolone and allopregnanolone (PubMed:23763432, PubMed:23161870).[UniProtKB/Swiss-Prot Function]

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