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BCMA (TNFRSF17) (NM_001192) Human Untagged Clone
CAT＃: SC125656
BCMA/TNFRSF17 (untagged)-Human tumor necrosis factor receptor superfamily, member 17 (BCMA/TNFRSF17)
CNY 2,400.00
CNY 2,950.00
| Cited in 3 publications. |
Product images
CNY 1,999.00
CNY 3,610.00
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | BCM; BCMA; CD269; TNFRSF13A |
| Vector | pCMV6-XL5 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data |
>OriGene sequence for NM_001192 edited
GAATTCTTGTAGAGATATTACTTGTCCTTCCAGGCTGTTCTTTCTGTAGCTC CCTTGTTTTCTTTTTGTGATCATGTTGCAGATGGCTGGGCAGTGCTCCCAAAATGAATAT TTTGACAGTTTGTTGCATGCTTGCATACCTTGTCAACTTCGATGTTCTTCTAATACTCCT CCTCTAACATGTCAGCGTTATTGTAATGCAAGTGTGACCAATTCAGTGAAAGGAACGAAT GCGATTCTCTGGACCTGTTTGGGACTGAGCTTAATAATTTCTTTGGCAGTTTTCGTGCTA ATGTTTTTGCTAAGGAAGATAAGCTCTGAACCATTAGAGGACGAGTTTAAAAACACAGGA TCAGGTCTCCTGGGCATGGCTAACATTGACCTGGAAAAGAGCAGGACTGGTGATGAAATT ATTCTTCCGAGAGGCCTCGAGTACACGGTGGAAGAATGCACCTGTGAAGACTGCATCAAG AGCAAACCGAAGGTCGACTCTGACCATTGCTTTCCACTCCCAGCTATGGAGGAAGGCGCA ACCATTCTTGTCACCACGAAAACGAATGACTATTGCAAGAGCCTGCCAGCTGCTTTGAGT GCTACGGAGATAGAGAAATCAATTTCTGCTAGGTAATTAACCATTTCGACTCGAGCAGTG CCACTTTAAAAATCTTTTGTCAGAATAGATGATGTGTCAGATCTCTTTAGGATGACTGTA TTTTTCAGTTGCCGATACAGCTTTTTGTCCTCTAACTGTGGAAACTCTTTATGTTAGATA TATTTCTCTAGGTTACTGTTGGGAGCTTAATGGTAGAAACTTCCTTGGTTTCATGATTAA AGTCTTTTTTTTTCCTGAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA AAAAAAAAAAAAAAAAAAAA >OriGene 5' read for NM_001192 unedited
TGTAGAGATTTACTTGTCCTTCCGGCTGTTCTTTCTGTAGCTCCCTTGTTTTCTTTTTGT GATCATGTTGCAGATGGCTGGGCAGTGCTCCCAAAATGAATATTTTGACAGTTTGTTGCA TGCTTGCATACCTTGTCAACTTCGATGTTCTTCTAATACTCCTCCTCTAACATGTCAGCG TTATTGTAATGCAAGTGTGACCAATTCAGTGAAAGGAACGAATGCGATTCTCTGGACCTG TTTGGGACTGAGCTTAATAATTTCTTTGGCAGTTTTCGTGCTAATGTTTTTGCTAAGGAA GATAAGCTCTGAACCATTAGAGGACGAGTTTAAAAACACAGGATCAGGTCTCCTGGGCAT GGCTAACATTGACCTGGAAAAGAGCAGGACTGGTGATGAAATTATTCTTCCGAGAGGCCT CGAGTACACGGTGGAAGAATGCACCTGTGAAGACTGCATCAAGAGCAAACCGAAGGTCGA CTCTGACCATTGCTTTCCACTCCCAGCTATGGAGGAAGGCGCAACCATTCTTGTCACCAC GAAAACGAATGACTATTGCAAGAGCCTGCCAGCTGCTTTGAGTGCTACGGAGATAGAGAA ATCAATTTCTGCTAGGTAATTAACCATTTCGACTCGAGCAGTGCCACTTTAAAAATCTTT TGTCAGAATAGATGATGTGTCAGATCTCTTTAGGATGACTGTATTTTTCAGTTGCCGATA CAGCTTTTTGTCCTCNTACTGTGGAAACTCTTTATGTTAGATATATTTCTCTAGGTTACT GTTGGGAGCTTAATGGTA |
| Restriction Sites | Please inquire |
| ACCN | NM_001192 |
| Insert Size | 1100 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Reference Data | |
| RefSeq | NM_001192.2, NP_001183.2 |
| RefSeq Size | 994 bp |
| RefSeq ORF | 555 bp |
| Locus ID | 608 |
| UniProt ID | Q02223 |
| Protein Families | Druggable Genome, Transmembrane |
| Protein Pathways | Cytokine-cytokine receptor interaction |
| Gene Summary | The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor is preferentially expressed in mature B lymphocytes, and may be important for B cell development and autoimmune response. This receptor has been shown to specifically bind to the tumor necrosis factor (ligand) superfamily, member 13b (TNFSF13B/TALL-1/BAFF), and to lead to NF-kappaB and MAPK8/JNK activation. This receptor also binds to various TRAF family members, and thus may transduce signals for cell survival and proliferation. [provided by RefSeq, Jul 2008] |
Citations (3)
| The use of this cDNA Clones has been cited in the following citations: |
|---|
|
?-secretase directly sheds the survival receptor BCMA from plasma cells
,Laurent, SA;Hoffmann, FS;Kuhn, PH;Cheng, Q;Chu, Y;Schmidt-Supprian, M;Hauck, SM;Schuh, E;Krumbholz, M;Rübsamen, H;Wanngren, J;Khademi, M;Olsson, T;Alexander, T;Hiepe, F;Pfister, HW;Weber, F;Jenne, D;Wekerle, H;Hohlfeld, R;Lichtenthaler, SF;Meinl, E;,
Nat Commun
,PubMed ID 26065893
[TNFRSF17]
|
|
The Immunoregulator Soluble TACI Is Released by ADAM10 and Reflects B Cell Activation in Autoimmunity
,Hoffmann, FS;Kuhn, PH;Laurent, SA;Hauck, SM;Berer, K;Wendlinger, SA;Krumbholz, M;Khademi, M;Olsson, T;Dreyling, M;Pfister, HW;Alexander, T;Hiepe, F;Kümpfel, T;Crawford, HC;Wekerle, H;Hohlfeld, R;Lichtenthaler, SF;Meinl, E;,
J. Immunol.
,PubMed ID 25505277
[TNFRSF17]
|
|
B-cell Maturation Antigen Is a Promising Target for Adoptive T-cell Therapy of Multiple Myeloma
,Robert O. Carpenter, Moses O. Evbuomwan, Stefania Pittaluga, Jeremy J. Rose, Mark Raffeld, Shicheng Yang, Ronald E. Gress, Frances T. Hakim, and James N. Kochenderfer,
Clin. Cancer Res., Apr 2013; 19: 2048 - 2060.
,PubMed ID 23344265
[TNFRSF17]
|
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Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC208851 | BCMA/TNFRSF17 (Myc-DDK-tagged)-Human tumor necrosis factor receptor superfamily, member 17 (BCMA/TNFRSF17) |
CNY 3,600.00 |
|
| RC208851L1 | Lenti ORF clone of Human tumor necrosis factor receptor superfamily, member 17 (BCMA/TNFRSF17), Myc-DDK-tagged |
CNY 6,000.00 |
|
| RC208851L2 | Lenti ORF clone of Human tumor necrosis factor receptor superfamily, member 17 (BCMA/TNFRSF17), mGFP tagged |
CNY 6,000.00 |
|
| RC208851L3 | Lenti ORF clone of Human tumor necrosis factor receptor superfamily, member 17 (BCMA/TNFRSF17), Myc-DDK-tagged |
CNY 6,000.00 |
|
| RC208851L4 | Lenti ORF clone of Human tumor necrosis factor receptor superfamily, member 17 (BCMA/TNFRSF17), mGFP tagged |
CNY 6,000.00 |
|
| RG208851 | BCMA/TNFRSF17 (tGFP-tagged) - Human tumor necrosis factor receptor superfamily, member 17 (BCMA/TNFRSF17) |
CNY 5,200.00 |
