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P2X3 (P2RX3) (NM_002559) Human Untagged Clone
CAT＃: SC123980
P2RX3 (untagged)-Human purinergic receptor P2X, ligand-gated ion channel, 3 (P2RX3)
CNY 5,488.00
| Cited in 2 publications. |
Product images
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | P2X3 |
| Vector | pCMV6-XL4 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data |
>OriGene sequence for NM_002559 edited
CCTGTCCTGTAGGACCTCCCTCTCCTGAGGCCACCACTGGGCCCCCTTCTGAGTGTCCCC TGAGCACTCTCTCAGCATGAACTGCATATCCGACTTCTTCACCTATGAGACCACCAAGTC GGTGGTTGTGAAGAGCTGGACCATCGGGATCATCAACCGAGTAGTTCAGCTTCTGATCAT CTCCTACTTTGTAGGGTGGGTTTTCTTGCACGAGAAGGCTTACCAGGTACGGGACACAGC CATTGAGTCCTCGGTGGTAACCAAGGTGAAGGGCTCCGGACTCTACGCCAACAGAGTCAT GGATGTGTCTGATTACGTGACGCCACCTCAGGGCACCTCGGTCTTTGTCATCATCACCAA GATGATTGTTACTGAAAATCAGATGCAAGGATTCTGCCCAGAGAGTGAGGAGAAATACCG CTGTGTATCAGACAGCCAGTGCGGGCCTGAGCGCTTGCCAGGTGGGGGGATCCTCACTGG CCGCTGCGTGAACTACAGCTCTGTGCTCCGGACCTGTGAGATCCAGGGCTGGTGCCCCAC GGAGGTGGACACAGTGGAAACGCCCATCATGATGGAAGCTGAGAACTTCACTATTTTCAT CAAGAACAGCATCCGTTTCCCCCTCTTCAACTTTGAGAAGGGAAACCTCCTTCCCAACCT GACAGCCAGGGACATGAAGACCTGCCGCTTCCACCCGGACAAGGACCCTTTCTGCCCCAT CTTGCGGGTAGGGGACGTGGTCAAGTTTGCGGGGCAGGATTTTGCCAAACTGGCGCGCAC GGGGGGAGTTCTGGGCATTAAGATCGGCTGGGTGTGCGACTTGGACAAGGCCTGGGACCA GTGCATCCCCAAATACTCCTTCACCCGGCTCGACAGCGTTTCTGAGAAAAGCAGCGTGTC CCCAGGCTACAACTTCAGGTTTGCCAAGTACTACAAAATGGAAAATGGCAGTGAGTACCG CACCCTCCTGAAGGCTTTTGGCATCCGCTTCGACGTGCTGGTATACGGGAATGCTGGCAA GTTCAACATCATCCCCACCATCATCAGCTCTGTGGCGGCCTTTACTTCTGTGGGAGTGGG AACTGTTCTCTGTGACATCATCCTGCTCAACTTCCTCAAGGGGGCCGACCAGTACAAAGC CAAGAAGTTTGAGGAGGTGAATGAGACTACACTGAAAATCGCGGCTTTGACCAACCCAGT GTACCCCAGCGACCAGACCACAGTGGAGAAGCAGTCCACCGATTCGGGGGCCTTCTCCAT AGGCCACTAGGGCCTCTTTCCAGGGCCCCACACTCACAAAGGCTCCAGGCCTCCCCACAG AGGACCCTGCCTGAGCAAGGGGGCATGGGACCTGTCCTGTAGGACCTCCCTCTCCTGAGG CCACCACTGGGCCCCCTTCTGAGTGTCCCCTGAGCACTCTCTCAGCATGAACTGCATATC CGACTTCTTCACCTATGAGACCACCAAGTCGGTGGTTGTGAAGAGCTGGACCATCGGGAT CATCAACCGAGTAGTTCAGCTTCTGATCATCTCCTACTTTGTAGGGTGGGTTTTCTTGCA CGAGAAGGCTTACCAGGTACGGGACACAGCCATTGAGTCCTCGGTGGTAACCAAGGTGAA GGGCTCCGGACTCTACGCCAACAGAGTCATGGATGTGTCTGATTACGTGACGCCACCTCA GGGCACCTCGGTCTTTGTCATCATCACCAAGATGATTGTTACTGAAAATCAGATGCAAGG ATTCTGCCCAGAGAGTGAGGAGAAATACCGCTGTGTATCAGACAGCCAGTGCGGGCCTGA GCGCTTGCCAGGTGGGGGGATCCTCACTGGCCGCTGCGTGAACTACAGCTCTGTGCTCCG GACCTGTGAGATCCAGGGCTGGTGCCCCACGGAGGTGGACACAGTGGAAACGCCCATCAT GATGGAAGCTGAGAACTTCACTATTTTCATCAAGAACAGCATCCGTTTCCCCCTCTTCAA CTTTGAGAAGGGAAACCTCCTTCCCAACCTGACAGCCAGGGACATGAAGACCTGCCGCTT CCACCCGGACAAGGACCCTTTCTGCCCCATCTTGCGGGTAGGGGACGTGGTCAAGTTTGC GGGGCAGGATTTTGCCAAACTGGCGCGCACGGGGGGAGTTCTGGGCATTAAGATCGGCTG GGTGTGCGACTTGGACAAGGCCTGGGACCAGTGCATCCCCAAATACTCCTTCACCCGGCT CGACAGCGTTTCTGAGAAAAGCAGCGTGTCCCCAGGCTACAACTTCAGGTTTGCCAAGTA CTACAAAATGGAAAATGGCAGTGAGTACCGCACCCTCCTGAAGGCTTTTGGCATCCGCTT CGACGTGCTGGTATACGGGAATGCTGGCAAGTTCAACATCATCCCCACCATCATCAGCTC TGTGGCGGCCTTTACTTCTGTGGGAGTGGGAACTGTTCTCTGTGACATCATCCTGCTCAA CTTCCTCAAGGGGGCCGACCAGTACAAAGCCAAGAAGTTTGAGGAGGTGAATGAGACTAC ACTGAAAATCGCGGCTTTGACCAACCCAGTGTACCCCAGCGACCAGACCACAGTGGAGAA GCAGTCCACCGATTCGGGGGCCTTCTCCATAGGCCACTAGGGCCTCTTTCCAGGGCCCCA CACTCACAAAGGCTCCAGGCCTCCCCACAGAGGACCCTGCCTGAGCAAGGGGGCATGGGA CCTGTCCTGTAGGACCTCCCTCTCCTGAGGCCACCACTGGGCCCCCTTCTGAGTGTCCCC TGAGCACTCTCTCAGCATGAACTGCATATCCGACTTCTTCACCTATGAGACCACCAAGTC GGTGGTTGTGAAGAGCTGGACCATCGGGATCATCAACCGAGTAGTTCAGCTTCTGATCAT CTCCTACTTTGTAGGGTGGGTTTTCTTGCACGAGAAGGCTTACCAGGTACGGGACACAGC CATTGAGTCCTCGGTGGTAACCAAGGTGAAGGGCTCCGGACTCTACGCCAACAGAGTCAT GGATGTGTCTGATTACGTGACGCCACCTCAGGGCACCTCGGTCTTTGTCATCATCACCAA GATGATTGTTACTGAAAATCAGATGCAAGGATTCTGCCCAGAGAGTGAGGAGAAATACCG CTGTGTATCAGACAGCCAGTGCGGGCCTGAGCGCTTGCCAGGTGGGGGGATCCTCACTGG CCGCTGCGTGAACTACAGCTCTGTGCTCCGGACCTGTGAGATCCAGGGCTGGTGCCCCAC GGAGGTGGACACAGTGGAAACGCCCATCATGATGGAAGCTGAGAACTTCACTATTTTCAT CAAGAACAGCATCCGTTTCCCCCTCTTCAACTTTGAGAAGGGAAACCTCCTTCCCAACCT GACAGCCAGGGACATGAAGACCTGCCGCTTCCACCCGGACAAGGACCCTTTCTGCCCCAT CTTGCGGGTAGGGGACGTGGTCAAGTTTGCGGGGCAGGATTTTGCCAAACTGGCGCGCAC GGGGGGAGTTCTGGGCATTAAGATCGGCTGGGTGTGCGACTTGGACAAGGCCTGGGACCA GTGCATCCCCAAATACTCCTTCACCCGGCTCGACAGCGTTTCTGAGAAAAGCAGCGTGTC CCCAGGCTACAACTTCAGGTTTGCCAAGTACTACAAAATGGAAAATGGCAGTGAGTACCG CACCCTCCTGAAGGCTTTTGGCATCCGCTTCGACGTGCTGGTATACGGGAATGCTGGCAA GTTCAACATCATCCCCACCATCATCAGCTCTGTGGCGGCCTTTACTTCTGTGGGAGTGGG AACTGTTCTCTGTGACATCATCCTGCTCAACTTCCTCAAGGGGGCCGACCAGTACAAAGC CAAGAAGTTTGAGGAGGTGAATGAGACTACACTGAAAATCGCGGCTTTGACCAACCCAGT GTACCCCAGCGACCAGACCACAGTGGAGAAGCAGTCCACCGATTCGGGGGCCTTCTCCAT AGGCCACTAGGGCCTCTTTCCAGGGCCCCACACTCACAAAGGCTCCAGGCCTCCCCACAG AGGACCCTGCCTGAGCAAGGGGGCATGGGA >OriGene 5' read for NM_002559 unedited
GAATACGACAGGCTATAGGGCGGCCGCGAATTCGGCACGAGCANGAGCCNANAATCTCAC TAGGATTGCATGGCTTAAAGGGACAGGCTCCCCATTCCTCCAACCCCTCTAAGCTGCCCC CTCCAGGTCGTGATCTCGTCTCCCTGTCCTGTAGGACCTCCCTCTCCTGAGGCCACCACT GGGCCCCCTTCTGAGTGTCCCCTGAGCACTCTCTCAGCATGAACTGCATATCCGACTTCT TCACCTATGAGACCACCAAGTCGGTGGTTGTGAAGAGCTGGACCATCGGGATCATCAACC GAGTAGTTCAGCTTCTGATCATCTCCTACTTTGTAGGGTGGGTTTTCTTGCACGAGAAGG CTTACCAGGTACGGGACACAGCCATTGAGTCCTCGGTGGTAACCAAGGTGAAGGGCTCCG GACTCTACGCCAACAGAGTCATGGATGTGTCTGATTACGTGACGCCACCTCAGGGCACCT CGGTCTTTGTCATCATCACCAAGATGATTGTTACTGAAAATCAGATGCAAGGATTCTGCC CAGAGAGTGAGGAGAAATACCGCTGTGTATCAGACAGCCAGTGCGGGCCTGAGCGCTTGC CAGGTGGNGGGATCCTCACTGGCCGCTGCGTGAACTACAGCTCTGTGCTCCGGACCTGTG AGATCCCAGGCTGGTGCCCCACCGAAGTGGACACAGTTNAAACGCCCATCATGATTGGAG CTGGAAACTTTCTATTTTTATTAAAAACAGTATCGTTTCCCCTTTTAAATTGAGAAGGAA ACCTCTTT >OriGene 3' read for NM_002559 unedited
TGTACCTGGAGGCACTGGGTTGGTCAAAGCCGCGATTTTCAGTGTNGNNNNNTTCACCTC CTCAAACTTCTTGGCTTTGTACTGGTCGGCCCCCTTGAGGAAGTTGAGCAGGATGATGTC ACAGAGAACAGTTCCCACTCCCACAGAAGTAAAGGCCGCCACAGAGCTGATGATGGTGGG GATGATGTTGAACTTGCCAGCATTCCCGTATACCAGCACGTCGAAGCGGATGCCAAAAGC CTTCAGGAGGGTGCGGTACTCACTGCCATTTTCCATTTTGTAGTACTTGGCAAACCTGAA GTTGTAGCCTGGGGACACGCTGCTTTTCTCAGAAACGCTGTCGAGCCGGGTGAAGGAGTA TTTGGGGATGCACTGGTCCCAGGCCTTGTCCAAGTCGCACACCCAGCCGATCTTAATGCC CAGAACTCCCCCCGTGCGCGCCAGTTTGGCAAAATCCTGCCCCGCAAACTTGACCACGTC CCCTACCCGCAAGATGGGGCAGAAAGGGTCCTTGTCCGGGTGGAAGCGGCAGGTCTTCAT GTCCCTGGCTGTCAGGTTGGGAAGGAGGTTTCCCTTCTCAAAGTTGAAGAGGGGGAAACG GATGCTGTTCTTGATGAAAATAGTGAAGTTCTCAGCTTCCATCATGATGGGCGTTTCCAC TGTGTCCACCTCCGTGGGGCACCAGCCCTGGATCTCACAGGTCCAGAGCACAGAGCTGTA GTTCACGCAGCGGCCAGTGAGGATCCCNCCACCTGCAGCGCTCAGCCCGCACTGCTGTCT GATCACAGCGTC |
| Restriction Sites | Please inquire |
| ACCN | NM_002559 |
| Insert Size | 3800 bp |
| OTI Disclaimer | Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at custsupport@origene.com or by calling 301.340.3188 option 3 for pricing and delivery. The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Reference Data | |
| RefSeq | NM_002559.2, NP_002550.2 |
| RefSeq Size | 1349 bp |
| RefSeq ORF | 1194 bp |
| Locus ID | 5024 |
| UniProt ID | P56373 |
| Protein Families | Druggable Genome, Ion Channels: ATP Receptors, Transmembrane |
| Protein Pathways | Calcium signaling pathway, Neuroactive ligand-receptor interaction |
| Gene Summary | This gene encodes a member of the P2X purinergic receptor (purinoceptor) gene family which includes seven members (P2RX1 - P2RX7). P2X purinoceptors are a family of cation-permeable, ligand-gated ion channels that open in response to the binding of extracellular adenosine 5'-triphosphate (ATP). The encoded protein is a subunit of the trimeric P2X3 receptor ion channel which is expressed by sensory or autonomic neurons. A deficiency of the orthologous protein in mice is associated with reduced pain-related behavior and urinary bladder hyporeflexia. [provided by RefSeq, Aug 2017] |
Citations (2)
| The use of this cDNA Clones has been cited in the following citations: |
|---|
|
Molecular mechanisms of human P2X3 receptor channel activation and modulation by divalent cation bound ATP
,Li, M;Wang, Y;Banerjee, R;Marinelli, F;Silberberg, S;Faraldo-Gómez, JD;Hattori, M;Swartz, KJ;,
Elife
,PubMed ID 31232692
[P2RX3]
|
|
Lidocaine Preferentially Inhibits the Function of Purinergic P2X7 Receptors Expressed in Xenopus Oocytes
,Okura, D;Horishita, T;Ueno, S;Yanagihara, N;Sudo, Y;Uezono, Y;Minami, T;Kawasaki, T;Sata, T;,
Anesth. Analg.
,PubMed ID 25695577
[P2RX3]
|
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Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC218626 | P2RX3 (Myc-DDK-tagged)-Human purinergic receptor P2X, ligand-gated ion channel, 3 (P2RX3) |
CNY 5,488.00 |
|
| RC218626L1 | Lenti ORF clone of Human purinergic receptor P2X, ligand-gated ion channel, 3 (P2RX3), Myc-DDK-tagged |
CNY 7,888.00 |
|
| RC218626L2 | Lenti ORF clone of Human purinergic receptor P2X, ligand-gated ion channel, 3 (P2RX3), mGFP tagged |
CNY 5,890.00 |
|
| RC218626L3 | Lenti ORF clone of Human purinergic receptor P2X, ligand-gated ion channel, 3 (P2RX3), Myc-DDK-tagged |
CNY 7,888.00 |
|
| RC218626L4 | Lenti ORF clone of Human purinergic receptor P2X, ligand-gated ion channel, 3 (P2RX3), mGFP tagged |
CNY 7,888.00 |
|
| RG218626 | P2RX3 (tGFP-tagged) - Human purinergic receptor P2X, ligand-gated ion channel, 3 (P2RX3) |
CNY 7,088.00 |
