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IL1 Receptor I (IL1R1) (NM_000877) Human Untagged Clone
CAT＃: SC119624
IL1R1 (untagged)-Human interleukin 1 receptor, type I (IL1R1)
CNY 2,950.00
| Cited in 2 publications. |
Product images
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | CD121A; D2S1473; IL-1R-alpha; IL1R; IL1RA; P80 |
| Vector | pCMV6-XL4 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data |
>OriGene sequence for NM_000877 edited
GAATTCGGCACGAGTCTCGCCCCTCTGAGCTGAGCCGGGTTCCGCCCGGGGCTGGGATCC CATCACCCTCCACGGCCGTCCGTCCAGGTAGACGCACCCTCTGAAGATGGTGACTCCCTC CTGAGAAGCTGGACCCCTTGGTAAAAGACAAGGCCTTCTCCAAGAAGAATATGAAAGTGT TACTCAGACTTATTTGTTTCATAGCTCTACTGATTTCTTCTCTGGAGGCTGATAAATGCA AGGAACGTGAAGAAAAAATAATTTTAGTGTCATCTGCAAATGAAATTGATGTTCGTCCCT GTCCTCTTAACCCAAATGAACACAAAGGCACTATAACTTGGTATAAAGATGACAGCAAGA CACCTGTATCTACAGAACAAGCCTCCAGGATTCATCAACACAAAGAGAAACTTTGGTTTG TTCCTGCTAAGGTGGAGGATTCAGGACATTACTATTGCGTGGTAAGAAATTCATCTTACT GCCTCAGAATTAAAATAAGTGCAAAATTTGTGGAGAATGAGCCTAACTTATGTTATAATG CACAAGCCATATTTAAGCAGAAACTACCCGTTGCAGGAGACGGAGGACTTGTGTGCCCTT ATATGGAGTTTTTTAAAAATGAAAATAATGAGTTACCTAAATTACAGTGGTATAAGGATT GCAAACCTCTACTTCTTGACAATATACACTTTAGTGGAGTCAAAGATAGGCTCATCGTGA TGAATGTGGCTGAAAAGCATAGAGGGAACTATACTTGTCATGCATCCTACACATACTTGG GCAAGCAATATCCTATTACCCGGGTAATAGAATTTATTACTCTAGAGGAAAACAAACCCA CAAGGCCTGTGATTGTGAGCCCAGCTAATGAGACAATGGAAGTAGACTTGGGATCCCAGA TACAATTGATCTGTAATGTCACCGGCCAGTTGAGTGACATTGCTTACTGGAAGTGGAATG GGTCAGTAATTGATGAAGATGACCCAGTGCTAGGGGAAGACTATTACAGTGTGGAAAATC CTGCAAACAAAAGAAGGAGTACCCTCATCACAGTGCTTAATATATCGGAAATTGAAAGTA GATTTTATAAACATCCTTTTACCTGTTTTGCCAAGAATACACATGGTATAGATGCAGCAT ATATCCAGTTAATATATCCAGTCACTAATTTCCAGAAGCACATGATTGGTATATGTGTCA CGTTGACAGTCATAATTGTGTGTTCTGTTTTCATCTATAAAATCTTCAAGATTGACATTG TGCTTTGGTACAGGGATTCCTGCTATGATTTTCTCCCAATAAAAGCTTCAGATGGAAAGA CCTATGACGCATATATACTGTATCCAAAGACTGTTGGGGAAGGGTCTACCTCTGACTGTG ATATTTTTGTGTTTAAAGTCTTGCCTGAGGTCTTGGAAAAACAGTGTGGATATAAGCTGT TCATTTATGGAAGGGATGACTACGTTGGGGAAGACATTGTTGAGGTCATTAATGAAAACG TAAAGAAAAGCAGAAGACTGATTATCATTTTAGTCAGAGAAACATCAGGCTTCAGCTGGC TGGGTGGTTCATCTGAAGAGCAAATAGCCATGTATAATGCTCTTGTTCAGGATGGAATTA AAGTTGTCCTGCTTGAGCTGGAGAAAATCCAAGACTATGAGAAAATGCCAGAATCGATTA AATTCATTAAGCAGAAACATGGGGCTATCCGCTGGTCAGGGGACTTTACACAGGGACCAC AGTCTGCAAAGACAAGGTTCTGGAAGAATGTCAGGTACCACATGCCAGTCCAGCGACGGT CACCTTCATCTAAACACCAGTTACTGTCACCAGCCACTAAGGAGAAACTGCAAAGAGAGG CTCACGTGCCTCTCGGGTAGCATGGAGAAGTTGCCAAGAGTTCTTTAGGTGCCTCCTGTC TTATGGCGTTGCAGGCCAGGTTATGCCTCATGCTGACTTGCAGAGTTCATGGAATGTAAC TATATCATCCTTTATCCCTGAGGTCACCTGGAATCAGATTATTAAGGGAATAAGCCATGA CGTCAATAGCAGCCCAGGGCACTTCAGAGTAGAGGGCTTGGGAAGATCTTTTAAAAAGGC AGTAGGCCCGGTGTGGTGGCTCACGCCTATAATCCCAGCACTTTGGGAGGCTGAAGTGGG TGGATCACCAGAGGTCAGGAGTTCGAGACCAGCCCAGCCAACATGGCAAAACCCCATCTC TACTAAAAATACAAAAATGAGCTAGGCATGGTGGCACACGCCTGTAATCCCAGCTACACC TGAGGCTGAGGCAGGAGAATTGCTTGAACCGGGGAGACGGAGGTTGCAGTGAGCCGAGTT TGGGCCACTGCACTCTAGCCTGGCAACAGAGCAAGACTCCGTCTCAAAAAAAGGGCAATA AATGCCCTCTCTGAATGTTTGAACTGCCAAGAAAAGGCATGGAGACAGCGAACTAGAAGA AAGGGCAAGAAGGAAATAGCCACCGTCTACAGATGGCTTAGTTAAGTCATCCACAGCCCA AGGGCGGGGCTATGCCTTGTCTGGGGACCCTGTAGAGTCACTGACCCTGGAGCGGCTCTC CTGAGAGGTGCTGCAGGCAAAGTGAGACTGACACCTCACTGAGGAAGGGAGACATATTCT TGGAGAACTTTCCATCTGCTTGTATTTTCCATACACATCCCCAGCCAGAAGTTAGTGTCC GAAGACCGAATTTTATTTTACAGAGCTTGAAAACTCACTTCAATGAACAAAGGGATTCTC CAGGATTCCAAAGTTTTGAAGTCATCTTAGCTTTCCACAGGAGGGAGAGAACTTAAAAAA GCAACAGTAGCAGGGAATTGATCCACTTCTTAATGCTTTCCTCCCTGGCATGACCATCCT GTCCTTTGTTATTATCCTGCATTTTACGTCTTTGGAGGAACAGCTCCCTAGTGGCTTCCT CCATCTGCAATGTCCCTTGCACAGCCCACACATGAACCATCCTTCCCATGATGCCGCTCT TCTGTCATCCCGCTCCTGCTGAAACACCTCCCAGGGGCTCCACCTGTTCAGGAGCTGAAG CCCATGCTTTCCCACCAGCATGTCACTCCCAGACCACCTCCCTGCCCTGTCCTCCAGCTT CCCCTCGCTGTCCTGCTGTGTGAATTCCCAGGTTGGCCTGGTGGCCATGTCGCCTGCCCT CAGCACTCCTCTGTCTCTGCTCTTGCCTGCACCCTTCCTCCTCCTTTGCCTAGGAGGCCT TCTCGCATTTTCTCTAGCTGATCAGAATTTTACCAAAATTCAGAACATCCTCCAATTCCA CAGTCTCTGGGAGACTTTCCCTAAGAGGCGACTTCCTCTCCAGCCTTCTCTCTCTGGTCA GGCCCACTGCAGAGATGGTGGTGAGCACATCTGGGAGGCTGGTCTCCCTCCAGCTGGAAT TGCTGCTCTCTGAGGGAGAGGCTGTGGTGGCTGTCTCTGTCCCTCACTGCCTTCCAGGAG CAATTTGCACATGTAACATAGATTTATGTAATGCTTTATGTTTAAAAACATTCCCCAATT ATCTTATTTAATTTTTGCAATTATTCTAATTTTATATATAGAGAAAGTGACCTATTTTTT AAAAAAATCACACTCTAAGTTCTATTGAACCTAGGACTTGAGCCTCCATTTCTGGCTTCT AGTCTGGTGTTCTGAGTACTTGATTTCAGGTCAATAACGGTCCCCCCTCACTCCACACTG GCACGTTTGTGAGAAGAAATGACATTTTGCTAGGAAGTGACCGAGTCTAGGAATGCTTTT ATTCAAGACACCAAATTCCAAACTTCTAAATGTTGGAATTTTCAAAAATTGTGTTTAGAT TTTATGAAAAACTCTTCTACTTTCATCTATTCTTTCCCTAGAGGCAAACATTTCTTAAAA TGTTTCATTTTCATTAAAAATGAAAGCCAAATTTATATGCCACCGATTGCAGGACACAAG CACAGTTTTAAGAGTTGTATGAACATGGAGAGGACTTTTGGTTTTTATATTTCTCGTATT TAATATGGGTGAACACCAACTTTTATTTGGAATAATAATTTTCCTCCTAAACAAAAACAC ATTGAGTTTAAGTCTCTGACTCTTGCCTTTCCACCTGCTTTCTCCTGGGCCCGCTTTGCC TGCTTGAAGGAACAGTGCTGTTCTGGAGCTGCTGTTCCAACAGACAGGGCCTAGCTTTCA TTTGACACACAGACTACAGCCAGAAGCCCATGGAGCAGGGATGTCACGTCTTGAAAAGCC TATTAGATGTTTTACAAATTTAATTTTGCAGATTATTTTAGTCTGTCATCCAGAAAATGT GTCAGCATGCATAGTGCTAAGAAAGCAAGCCAATTTGGAAACTTAGGTTAGTGACAAAAT TGGCCAGAGAGTGGGGGTGATGATGACCAAGAATTACAAGTAGAATGGCAGCTGGAATTT AAGGAGGGACAAGAATCAATGGATAAGCGTGGGTGGAGGAAGATCCAAACAGAAAAGTGC AAAGTTATTCCCCATCTTCCAAGGGTTGAATTCTGGAGGAAGAAGACACATTCCTAGTTC CCCGTGAACTTCCTTTGACTTATTGTCCCCACTAAAACAAAACAAAAAACTTTTAATGCC TTCCACATTAATTAGATTTTCTTGCAGTTTTTTTATGGCATTTTTTTAAAGATGCCCTAA GTGTTGAAGAAGAGTTTGCAAATGCAACAAAATATTTAATTACCGGTTGTTAAAACTGGT TTAGCACAATTTATATTTTCCCTCTCTTGCCTTTCTTATTTGCAATAAAAGGTATTGAGC CATTTTTTAAATGACATTTTTGATAAATTATGTTTGTACTAGTTGATGAAGGAGTTTTTT TTAACCTGTTTATATAATTTTGCAGCAGAAGCCAAATTTTTTGTATATTAAAGCACCAAA TTCATGTACAGCATGCATCACGGATCAATAGACTGTACTTATTTTCCAATAAAATTTTCA AACTTTAAAAAAAAAAAAAAAAAACTCGAC >OriGene 5' read for NM_000877 unedited
CGCGAATTCGGCACGAGTCTCGCCCCTCTGAGCTGAGCCGGGTTCCGCCCGGGGCTGGGA TCCCATCACCCTCCACGGCCGTCCGTCCAGGTAGACGCACCCTCTGAAGATGGTGACTCC CTCCTGAGAAGCTGGACCCCTTGGTAAAAGACAAGGCCTTCTCCAAGAAGAATATGAAAG TGTTACTCAGACTTATTTGTTTCATAGCTGTACTGATTTCTTCTCTGGAGGCTGATAAAT GCAAGGAACGTGAAGAAAAAATAATTTTAGTGTCATCTGCAAATGAAATTGATGTTCGTC CCTGTCCTCTTAACCCAAATGAACACAAAGGCACTATAACTTGGTATAAAGATGACAGCA AGACACCTGTATCTACAGAACAAGCCTCCAGGATTCATCAACACAAAGAGAAACTTTGGT TTGTTCCTGCTAAGGTGGAGGATTCAGGACATTACTATTGCGTGGTAAGAAATTCATCTT ACTGCCTCAGAATTAAAATAAGTGCAAAATTTGTGGAGAATGAGCCTAACTTATGTTATA ATGCACAAGCCATATTTAAGCAGAAACTACCCGTTGCAGGAGACGGAGGACTTGTGTGCC CTTATATGGAGTTTTTTAAAAATGAAAATAATGAGTTACCTAAATTACAGTGGTATAAGG ATTGCAAACCTCTACTTCTTGANCATATACACTNTAAGTGGAGTCAAAGATAGGGCTCAT CGTGAATGAATGGTGGCTGAA >OriGene 3' read for NM_000877 unedited
TTTGGACGCGGCCGCTTTCTAAAGTCGGTTTTTTTTTTTTTTTTTTAAAGTTTGAAAATT TTATCTGGAAAATAAGTACANGTCTATTAGATCCGTGATGCATAGCTGTACATGAAATTT GGTAGCTTTAATATACAAAAAATTTGGCTCTCTGCTGCAAAATTATATAAACAGGTTAAA AAAAACTCCTTCATCAACTAGTACAAACATAATTTATCAAAAATGTCATTTAAAAAATGG CTCAATACCTTTTATTGCAAATAAGAAAGGCAAGAGAGGGAAAATATAAATTGTGCTAAA CCAGTTTTAACAACCGGTAATTAAATATTTTGTTGCATTTGCAAACTCTTCTTCAACACT TAGGGCATCTTTAAAAAAATGCCATAAAAAAACTGCAAGAAAATCTAATTAATGTGGAAG GCATTAAAAGTTTTTTGTTTTGTTTTAGTGGGGACAATAAGTCAAAGGAAGTTCACGGGG AACTAGGAATGTGTCTTCTTCCTCCAGAATTCAACCCTTGGAAGATGGGGAATAACTTTG CACTTTTCTGTTTGGATCTTCCTCCACCCACGCTTATCCATTGATTCTTGTCCCTCCTTA AATTCCAGCTGCCATTCTACTTGTAATTCTTGGTCATCATCACCCCCACTCTCTGGCCAA TTTTGTCACTAACCTAAGTTTCCAAATTGGCTTGCTTTCTTAGCACTATGCATGCTGACA CATTCTCTGGATGACAGACTAAAATAATCTGGAAAATAAATTTGGAAAACATCAAATAAG CTTTTCAAGACGTGACATCCCTGCCCCAGGGCCTTCTGGCTGTATCCCGGGGGTCAAATG AAACCCAGCCCTGGCCGGGGGACAGCAGCTCAGAAAACCCTGGTCCTTAAGCGGCAAAGG GGCCCAGCAAAACCCGGGGCAAAGGCAAATCACACCTTATACCCCGGGTTTTTGTTAACA GAAAT |
| Restriction Sites | NotI-NotI |
| ACCN | NM_000877 |
| Insert Size | 4890 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Reference Data | |
| RefSeq | NM_000877.2, NP_000868.1 |
| RefSeq Size | 4909 bp |
| RefSeq ORF | 1710 bp |
| Locus ID | 3554 |
| UniProt ID | P14778 |
| Domains | TIR, IG |
| Protein Families | Druggable Genome, Transmembrane |
| Protein Pathways | Apoptosis, Cytokine-cytokine receptor interaction, Hematopoietic cell lineage, MAPK signaling pathway |
| Gene Summary | This gene encodes a cytokine receptor that belongs to the interleukin-1 receptor family. The encoded protein is a receptor for interleukin-1 alpha, interleukin-1 beta, and interleukin-1 receptor antagonist. It is an important mediator involved in many cytokine-induced immune and inflammatory responses. This gene is located in a cluster of related cytokine receptor genes on chromosome 2q12. [provided by RefSeq, Dec 2013] Transcript Variant: This variant (1) is transcribed from a downstream promoter compared to variant 2. |
Citations (2)
| The use of this cDNA Clones has been cited in the following citations: |
|---|
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GABAA currents are decreased by IL-1ß in epileptogenic tissue of patients with temporal lobe epilepsy: implications for ictogenesis
,Roseti, C;van Vliet, EA;Cifelli, P;Ruffolo, G;Baayen, JC;Di Castro, MA;Bertollini, C;Limatola, C;Aronica, E;Vezzani, A;Palma, E;,
Neurobiol. Dis.
,PubMed ID 26168875
[IL1R1]
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Kinetic Approach to Pathway Attenuation Using XOMA 052, a Regulatory Therapeutic Antibody That Modulates Interleukin-1ß Activity
,Marina K. Roell, Hassan Issafras, Robert J. Bauer, Kristen S. Michelson, Nerissa Mendoza, Sandra I. Vanegas, Lisa M. Gross, Paul D. Larsen, Daniel H. Bedinger, David J. Bohmann, Genevieve H. Nonet, Naichi Liu, Steve R. Lee, Masahisa Handa, Seema S. Kantak, Arnold H. Horwitz, John J. Hunter, Alexander M. Owyang, Amer M. Mirza, John A. Corbin, and Mark L. White,
J. Biol. Chem., Jul 2010; 285: 20607 - 20614
[IL1R1]
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Other Versions
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| RC210412 | IL1R1 (Myc-DDK-tagged)-Human interleukin 1 receptor, type I (IL1R1) |
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| RC210412L1 | Lenti ORF clone of Human interleukin 1 receptor, type I (IL1R1), Myc-DDK-tagged |
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| RC210412L2 | Lenti ORF clone of Human interleukin 1 receptor, type I (IL1R1), mGFP tagged |
CNY 6,460.00 |
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| RC210412L3 | Lenti ORF clone of Human interleukin 1 receptor, type I (IL1R1), Myc-DDK-tagged |
CNY 6,460.00 |
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| RC210412L4 | Lenti ORF clone of Human interleukin 1 receptor, type I (IL1R1), mGFP tagged |
CNY 6,460.00 |
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| RG210412 | IL1R1 (tGFP-tagged) - Human interleukin 1 receptor, type I (IL1R1) |
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