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Lactoferrin (LTF) (NM_002343) Human Untagged Clone
CAT＃: SC118685
LTF (untagged)-Human lactotransferrin (LTF), transcript variant 1
CNY 2,950.00
| Cited in 2 publications. |
Product images
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | GIG12; HEL110; HLF2; LF |
| Vector | pCMV6-XL5 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data |
>OriGene ORF within SC118685 sequence for NM_002343 edited (data generated by NextGen Sequencing)
ATGAAACTTGTCTTCCTCGTCCTGCTGTTCCTCGGGGCCCTCGGACTGTGTCTGGCTGGC CGTAGGNNGAGTGTTCAGTGGTGCACCGTATCCCAACCCGAGGCCACAAAATGCTTCCAA TGGCAAAGGAATATGAGAAGAGTGCGTGGCCCTCCTGTCAGCTGCATAAAGAGAGACTCC CCCATCCAGTGTATCCAGGCCATTGCGGAAAACAGGGCCGATGCTGTGACCCTTGATGGT GGTTTCATATACGAGGCAGGCCTGGCCCCCTACAAACTGCGACCTGTAGCGGCGGAAGTC TACGGGACCGAAAGACAGCCACGAACTCACTATTATGCCGTGGCTGTGGTGAAGAAGGGC GGCAGCTTTCAGCTGAACGAACTGCAAGGTCTGAAGTCCTGCCACACAGGCCTTCGCAGG ACCGCTGGATGGAATGTCCCTATAGGGACACTTCGTCCATTCTTGAATTGGACGGGTCCA CCTGAGCCCATTGAGGCAGCTGTGGCCAGGTTCTTCTCAGCCAGCTGTGTTCCCGGTGCA GATAAAGGACAGTTCCCCAACCTGTGTCGCCTGTGTGCGGGGACAGGGGAAAACAAATGT GCCTTCTCCTCCCAGGAACCGTACTTCAGCTACTCTGGTGCCTTCAAGTGTCTGAGAGAC GGGGCTGGAGACGTGGCTTTTATCAGAGAGAGCACAGTGTTTGAGGACCTGTCAGACGAG GCTGAAAGGGACGAGTATGAGTTACTCTGCCCAGACAACACTCGGAAGCCAGTGGACAAG TTCAAAGACTGCCATCTGGCCCGGGTCCCTTCTCATGCCGTTGTGGCACGAAGTGTGAAT GGCAAGGAGGATGCCATCTGGAATCTTCTCCGCCAGGCACAGGAAAAGTTTGGAAAGGAC AAGTCACCGAAATTCCAGCTCTTTGGCTCCCCTAGTGGGCAGAAAGATCTGCTGTTCAAG GACTCTGCCATTGGGTTTTCGAGGGTGCCCCCGAGGATAGATTCTGGGCTGTACCTTGGC TCCGGCTACTTCACTGCCATCCAGAACTTGAGGAAAAGTGAGGAGGAAGTGGCTGCCCGG CGTGCGCGGGTCGTGTGGTGTGCGGTGGGCGAGCAGGAGCTGCGCAAGTGTAACCAGTGG AGTGGCTTGAGCGAAGGCAGCGTGACCTGCTCCTCGGCCTCCACCACAGAGGACTGCATC GCCCTGGTGCTGAAAGGAGAAGCTGATGCCATGAGTTTGGATGGAGGATATGTGTACACT GCAGGCAAATGTGGTTTGGTGCCTGTCCTGGCAGAGAACTACAAATCCCAACAAAGCAGT GACCCTGATCCTAACTGTGTGGATAGACCTGTGGAAGGATATCTTGCTGTGGCGGTGGTT AGGAGATCAGACACTAGCCTTACCTGGAACTCTGTGAAAGGCAAGAAGTCCTGCCACACC GCCGTGGACAGGACTGCAGGCTGGAATATCCCCATGGGCCTGCTCTTCAACCAGACGGGC TCCTGCAAATTTGATGAATATTTCAGTCAAAGCTGTGCCCCTGGGTCTGACCCGAGATCT AATCTCTGTGCTCTGTGTATTGGCGACGAGCAGGGTGAGAATAAGTGCGTGCCCAACAGC AATGAGAGATACTACGGCTACACTGGGGCTTTCCGGTGCCTGGCTGAGAATGCTGGAGAC GTTGCATTTGTGAAAGATGTCACTGTCTTGCAGAACACTGATGGAAATAACAATGAGGCA TGGGCTAAGGATTTGAAGCTGGCAGACTTTGCGCTGCTGTGCCTCGATGGCAAACGGAAG CCTGTGACTGAGGCTAGAAGCTGCCATCTTGCCATGGCCCCGAATCATGCCGTGGTGTCT CGGATGGATAAGGTGGAACGCCTGAAACAGGTGCTGCTCCACCAACAGGCTAAATTTGGG AGAAATGGATCTGACTGCCCGGACAAGTTTTGCTTATTCCAGTCTGAAACCAAAAACCTT CTGTTCAATGACAACACTGAGTGTCTGGCCAGACTCCATGGCAAAACAACATATGAAAAA TATTTGGGACCACAGTATGTCGCAGGCATTACTAATCTGAAAAAGTGCTCAACCTCCCCC CTCCTGGAAGCCTGTGAATTCCTCAGGAAGTAA Clone variation with respect to NM_002343.3 67 a=>n;68 g=>n;85 g=>a;140 a=>g;1623 c=>t;1894 t=>c >OriGene 5' read for NM_002343 unedited
GTCAAAATTTGTATACGACTCACTATAGGCGGCCGCGATTCGGCACGAGGAGCAAACCCA CCTGCCCTAACTGGCTCCTAGGCACCTTCAAGTCATCTGCTGAAGAAGATAGCAGTCTCA CAGGTCAAGGCGATCTTCAAGTAAAGACCCTCTGCTCTGTGTCCTGCCCTCTAGAAGGCA CTGAGACCAGAGCTGGGACAGGGCTCAGGGGGCTGCGACTCCTAGGGGCTTGCAGACTAG TGGGAGAGAAAGAACATCGCAGCAGCCAGGCAGAACCAGGACAGGTGAGGTGCAGGCTGG CTTTCCTCTCGCAGCGCGGTGTGGAGTCCTGTCCTGCCTCAGGGCTTTTCGGAGCCTGGA TCCTCAAGGAACAAGTAGACCTGGCCGCGGGGAGTGGGGAGGGAAGGGGTGTCTATTGGG CAACAGGGCGGGGCAAAGCCCTGAATAAAGGGGCGCAGGGCAGGCGCAAGTGGCAGAGCC TTCGTTTGCCAAGTCGCCTCCAGACCGCAGACATGAAACTTGTCTTCCTCGTCCTGCTGT TCCTCGGGGCCCTCGGACTGTGTCTGGCTGGCCGTAGGAGAAGGAGTGTTCAGTGGTGCA CCGTATCCCAACCCGAGGCCACAAAATGCTTCCAATGGCAAAGGAATATGAGAAGAGTGC GTGGCCCTCCTGTCAGCTGCATAAAGAGAGACTCCCCCATCCAGTGTATCCAGGCCATTG CGGAAAACAGGGCCGATGCTGTGACCCTTNGATGGTGGTTTCATATACGAAGCAGGCCTG GCCCCCTACAACTGCGACCTGTAGCGGCGGAAGTCTACGGGACCGAAAGACAGCCACGAA CTCACTATTATGCCCGTGGNCTGTGGTGAAGAAAGGCNGGCAGCTNTCAGCTGAACGAAC TNNGCAGTCTGAAGTCCTGCCACACAGCCTTC >OriGene 3' read for NM_002343 unedited
ATGGACCGGCGGCCGCAATCTAGGATCGAGTTTTTTTTTTTTTTTTTTTTTTTTTTTTTT TTTTTTTTTTTTTTTTTTTTTTTTATCAACAAAATTTCTCATTTTACTTTTTGCTAAAAC CACAGCAGGGAATTGTAAGCAAATGGATGGGCAATCCCCACCTTCAGCAGGGGAGGCCAA GGCCCCAACACACCTGGGGAAAAAAAGCTGGGGGCAGTGAATGGCTGAGGCTTTTTTGGG GAGCTGGGCCATCTTTTTCGGTTTTACTTCCTGAGGAATTCACAGGGCTTTTCCAGAGAG GGGGGAGGTTGAGCACTTTTTACAAATTAATAATGCCTGCGACATACTGTGGTGCCCAAA AATATTTTTTTATATAATTGGTNNGNCGCCNCCNNCCNCCCCCCCCNTNCCCCCTCCCCC CCCCCCCTCTCGTCCCTCGCTCTTCTCCCCCTTCATCTTCTATTCTACCCATTCGTCTTC TCCCCATCTCTTCCCCCATCCCTCTCCACCCCCCCTCTTCTTCCCCCCTCCCCCCCCCGC TTCTTTTTATCCCTCTTCCTCCCCCCGTATTCCTTTCCACCCCCCCCTTCCCCTCTCCCC CTCCTCCCCCTTTTTCCCCCCCTCCCCTCTTCCCTCTCCCCTTTTTTCCCCCCCCTTTTC TTCCCCCTTTCCCCCTTCCCCTTTCCTTCTTGTCCCCTCTTCTCTCTCCCGCCTTTCCTT CCTCCCTTCCCCATTCTCTTCCCCTCCCTTTCTTTTCCCCTTCCTCTCCTCCTTTCTTTT CCCCTTCCCCCTCTCTACCCTATTTCCCCCCCCATTTCTTTTCCCCCCCCTTTTTTATTT TCCTTCTCCCCTTCCTCCCCCCTTCCATTTCCTTCCATTCCCTCCCTCTC |
| Restriction Sites | NotI-NotI |
| ACCN | NM_002343 |
| Insert Size | 2870 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Reference Data | |
| RefSeq | NM_002343.1, NP_002334.1 |
| RefSeq Size | 2619 bp |
| RefSeq ORF | 2136 bp |
| Locus ID | 4057 |
| UniProt ID | P02788 |
| Domains | TR_FER |
| Protein Families | Druggable Genome, Protease, Secreted Protein |
| Gene Summary | This gene is a member of the transferrin family of genes and its protein product is found in the secondary granules of neutrophils. The protein is a major iron-binding protein in milk and body secretions with an antimicrobial activity, making it an important component of the non-specific immune system. The protein demonstrates a broad spectrum of properties, including regulation of iron homeostasis, host defense against a broad range of microbial infections, anti-inflammatory activity, regulation of cellular growth and differentiation and protection against cancer development and metastasis. Antimicrobial, antiviral, antifungal and antiparasitic activity has been found for this protein and its peptides. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2014] Transcript Variant: This variant (1) encodes the longest isoform (1). |
Citations (2)
| The use of this cDNA Clones has been cited in the following citations: |
|---|
|
Lactoferrin Contributes a Renoprotective Effect in Acute Kidney Injury and Early Renal Fibrosis
,Hsu, YH;Chiu, IJ;Lin, YF;Chen, YJ;Lee, YH;Chiu, HW;,
Pharmaceutics
,PubMed ID 32397266
[LTF]
|
|
Re-expression of Lactotransferrin, a candidate tumor suppressor inactivated by promoter hypermethylation, impairs the malignance of oral squamous cell carcinoma cells
,Zhang, J;Ling, T;Wu, H;Wang, K;,
J. Oral Pathol. Med.
,PubMed ID 25370482
[LTF]
|
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Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC203140 | LTF (Myc-DDK-tagged)-Human lactotransferrin (LTF), transcript variant 1 |
CNY 3,990.00 |
|
| RC203140L1 | Lenti ORF clone of Human lactotransferrin (LTF), transcript variant 1, Myc-DDK-tagged |
CNY 5,890.00 |
|
| RC203140L2 | Lenti ORF clone of Human lactotransferrin (LTF), transcript variant 1, mGFP tagged |
CNY 5,890.00 |
|
| RC203140L3 | Lenti ORF clone of Human lactotransferrin (LTF), transcript variant 1, Myc-DDK-tagged |
CNY 5,890.00 |
|
| RC203140L4 | Lenti ORF clone of Human lactotransferrin (LTF), transcript variant 1, mGFP tagged |
CNY 5,890.00 |
|
| RG203140 | LTF (tGFP-tagged) - Human lactotransferrin (LTF), transcript variant 1 |
CNY 4,370.00 |
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