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Nectin 2 (NECTIN2) (NM_002856) Human Untagged Clone
CAT＃: SC118376
PVRL2 (untagged)-Human poliovirus receptor-related 2 (herpesvirus entry mediator B) (PVRL2), transcript variant alpha
CNY 5,488.00
| Cited in 1 publication. |
Product images
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | CD112; HVEB; PRR2; PVRL2; PVRR2 |
| Vector | pCMV6-XL5 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data |
>OriGene sequence for NM_002856 edited
GAATTCGGCACGAGGGCCGGGGGTGCCGAGCCGGGCGGGGAGAGCTGGGCCGGGAGAGCA GAACAGGGAGGCTAGAGCGCAGCGGGAACCGGCCCGGAGCCGGAGCCGGAGCCCCACAGG CACCTACTAAACCGCCCAGCCGATCGGCCCCCACAGAGTGGCCCGCGGGCCTCCGGCCGG GCCCAGTCCCCTCCCGGGCCCTCCATGGCCCGGGCCGCTGCCCTCCTGCCGTCGAGATCG CCGCCGACGCCGCTGCTGTGGCCGCTGCTGCTGCTGCTGCTCCTGGAAACCGGAGCCCAG GATGTGCGAGTTCAAGTGCTACCCGAGGTGCGAGGCCAGCTCGGGGGCACCGTGGAGCTG CCGTGCCACCTGCTGCCACCTGTTCCTGGACTGTACATCTCCCTGGTGACCTGGCAGCGC CCAGATGCACCTGCGAACCACCAGAATGTGGCCGCCTTCCACCCTAAGATGGGTCCCAGC TTCCCCAGCCCGAAGCCTGGCAGCGAGCGGCTGTCCTTCGTCTCTGCCAAGCAGAGCACT GGGCAAGACACAGAGGCAGAGCTCCAGGACGCCACGCTGGCCCTCCACGGGCTCACGGTG GAGGACGAGGGCAACTACACTTGCGAGTTTGCCACCTTCCCCAAGGGGTCCGTCCGAGGG ATGACCTGGCTCAGAGTCATAGCCAAGCCCAAGAACCAAGCTGAGGCCCAGAAGGTCACG TTCAGCCAGGACCCTACGACAGTGGCCCTCTGCATCTCCAAAGAGGGCCGCCCACCTGCC CGGATCTCCTGGCTCTCATCCCTGGACTGGGAAGCCAAAGAGACTCAGGTGTCAGGGACC CTGGCCGGAACTGTCACTGTCACCAGCCGCTTCACCTTGGTGCCCTCGGGCCGAGCAGAT GGTGTCACGGTCACCTGCAAAGTGGAGCATGAGAGCTTCGAGGAACCAGCCCTGATACCT GTGACCCTCTCTGTACGCTACCCTCCTGAAGTGTCCATCTCCGGCTATGATGACAACTGG TACCTCGGCCGTACTGATGCCACCCTGAGCTGTGACGTCCGCAGCAACCCAGAGCCCACG GGCTATGACTGGAGCACGACCTCAGGCACCTTCCCGACCTCCGCAGTGGCCCAGGGCTCC CAGCTGGTCATCCACGCAGTGGACAGTCTGTTCAATACCACCTTCGTCTGCACAGTCACC AATGCCGTGGGCATGGGCCGCGCTGAGCAGGTCATCTTTGTCCGAGAAACCCCCAGGGCC TCGCCCCGAGATGTGGGCCCGCTGGTGTGGGGGGCCGTGGGGGGGACACTGCTGGTGCTG CTGCTTCTGGCTGGGGGGTCCTTGGCCTTCATCCTGCTGAGGGTGAGGAGGAGGAGGAAG AGCCCTGGAGGAGCAGGAGGAGGAGCCAGTGGCGACGGGGGATTCTACGATCCGAAAGCT CAGGTGTTGGGAAATGGGGACCCCGTCTTCTGGACACCAGTAGTCCCTGGTCCCATGGAA CCAGATGGCAAGGATGAGGAGGAGGAGGAGGAGGAAGAGAAGGCAGAGAAAGGCCTCATG TTGCCTCCACCCCCAGCACTCGAGGATGACATGGAGTCCCAGCTGGACGGCTCCCTCATC TCACGGCGGGCAGTTTATGTGTGACCTGGACACAGACAGAGACAGAGCCAGGCCCGGCCC TCCCGCCCCCGACCTGACCACGCCGGCCTAGGGTTCCAGACTGGTTGGACTTGTTCGTCT GGACGACACTGGAGTGGAACACTGCCTCCCACTTTCTTGGGACTTGGAGGGAGGTGGAAC AGCACACTGGACTTCTCCCGTCTCTAGGGCTGCATGGGGAGCCCGGGGAGCTGAGTAGTG GGGATCCAGAGAGGACCCCCGCCCCCAGAGACTTGGTTTTGGCTCCAGCCTTCCCCTGGC CCCGTGACACTCAGGAGTTAATAAATGCCTTGGAGGAAAAAAAAAAAAAAAAAAAAAAAA CTCGAC >OriGene 5' read for NM_002856 unedited
TTCACCATTTGTATACGACTCATATAGGCGGCCGCGNAATTCGCACGAGGGCCGGGGGTG CCGAGCCGGGCGGGNGAGACTGGGCCGGGAGAGCAGAACAGGAGGCTAGAGCGCAGCGGG AACCGGCCCGGAGCCGGAGCCGGAGCCCCACAGGCACCTACTAAACCGCCCAGCCGATCG GCCCCCACAGAGTGGCCCGCGGGCCTCCGGCCGGGCCCAGTCCCCTCCCGGGCCCTCCAT GGCCCGGGCCGCTGCCCTCCTGCCGTCGAGATCGCCGCCGACGCCGCTGCTGTGGCCGCT GCTGCTGCTGCTGCTCCTGGAAACCGGAGCCCAGGATGTGCGAGTTCAAGTGCTACCCGA GGTGCGAGGCCAGCTCGGGGGCACCGTGGAGCTGCCGTGCCACCTGCTGCCACCTGTTCC TGGACTGTACATCTCCCTGGTGACCTGGCAGCGCCCAGATGCACCTGCGAACCACCAGAA TGTGGCCGCCTTCCACCCTAAGATGGGTCCCAGCTTCCCCAGCCCGAAGCCTGGCAGCGA GCGGCTGTCCTTCGTCTCTGCCAAGCAGAGCACTGGGCAAGACACAGAGGCAGAGCTCCA GGACGCCACGCTGGCCCTCCACGGGCTCACGGTGGAGGACGAGGGCAACTACACTTGCGA GTTTGCCACCTTCCCCAAGGGTCCGTCCGAGGGATGACCTGNCTCAGAGTCATAGCCAAG CCCAGAACCAAGCTGAGGCCCAGAAAGTCACGTTCAGCCAGGACCCTACGACAGTGGCCC TCTGCATCTCCAAGAAGGCCGGCCACCTGCCCGAACTCCTGCCTCTCATCCCTGGACTGG GAACCAAAGAGACTCCAGTGTCAGGGACCCTGGCCCGAACTGTACTGTCACCAGCCGCTT CACCTTGTGCCCT >OriGene 3' read for NM_002856 unedited
CGCGGGCCGCAATCTAGAGTCGAGTTTTTTTTTTTTTTTTTTTTTTTTCCTCCAGGCATT TATTAACTCCTGAGTGTCACGGGGCCAGGGGAAGGCTGGAGCCAAAACCAAGTCTCTGGG GGCGGGGGTCCTCTCTGGATCCCCACTACTCAGCTCCCCGGGCTCCCCATGCAGCCCTAG AGACGGGAGAAGTCCAGGGGGCTGTTCCACCTACCTCCAAGTCCCAAGAAAGGGGGAGGC AGTGCCCCACTCCAGGGCCGCTCAGACGAACAAGTCCAACCAGTCTGGACCCCTAGGCCG ACGTGGACAGGCCGGGGGCGGAAGGAACGGTCACTGCTCTGAATCTGACTGCGCCCACAC CACACATTAACCGAACCCTTGAGACATGAGGGAATCAAACCCCTGGCAACCACTGCCACA ACACAACGCTGGGGGAGGCGGCTACATCGGCTATTTTTTTGCTCACTCTCTCTCCCCCGA CCTCCCCTATCTTGCTCTTTGCTCACCGGAATCTCCGCCCTCTGCCCCCTTTATTAGGGT TCTCTTTTCACTCTCTCACCCCTTCCCCATCCTCAACTCCCTCTCTCCCTGCCCCCCCTC CCCGTACCTCCGGCTGTTTCTCATTCCCCCCCTTTCCCCTGTCAGGGCACTCTCCGCTTT CCGCCCGGCAATTATTCTCTTCTTCCCCTCTTCGTCGTCGATCTTTATTTTCTTCTTTAA TCCTTCAGTCCCTCTGGACTTCTCCCTCACACGCTTGCACTTTTACATATGTATCCTCCA CAATGTCCCTCCCTCCTCAACGCCCCACCCTCAATCTCCCTCATCCTGCGTACCTATCCC CCCCCCGCCCTCGCCTGTTGCTTTCTCGTCCTACCAGTCTCCATTACTTTTCCACTCTTA CCCTGACTCTCATTTCCCCCCACATTG |
| Restriction Sites | NotI-NotI |
| ACCN | NM_002856 |
| Insert Size | 1910 bp |
| OTI Disclaimer | Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at custsupport@origene.com or by calling 301.340.3188 option 3 for pricing and delivery. The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Reference Data | |
| RefSeq | NM_002856.1, NP_002847.1 |
| RefSeq Size | 1928 bp |
| RefSeq ORF | 1440 bp |
| Locus ID | 5819 |
| UniProt ID | Q92692 |
| Domains | ig, IGv, IG |
| Protein Families | Druggable Genome, Transmembrane |
| Protein Pathways | Adherens junction, Cell adhesion molecules (CAMs) |
| Gene Summary | This gene encodes a single-pass type I membrane glycoprotein with two Ig-like C2-type domains and an Ig-like V-type domain. This protein is one of the plasma membrane components of adherens junctions. It also serves as an entry for certain mutant strains of herpes simplex virus and pseudorabies virus, and it is involved in cell to cell spreading of these viruses. Variations in this gene have been associated with differences in the severity of multiple sclerosis. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq, Jul 2008] Transcript Variant: This variant (alpha) has multiple differences in the coding region, compared to variant delta, one of which results in an early stop codon. The resulting protein (isoform alpha) has a distinct C-terminus and is shorter than isoform delta. |
Citations (1)
| The use of this cDNA Clones has been cited in the following citations: |
|---|
|
Histone Deacetylase 5 Is Overexpressed in Scleroderma Endothelial Cells and Impairs Angiogenesis via Repression of Proangiogenic Factors
,Tsou, PS;Wren, JD;Amin, MA;Schiopu, E;Fox, DA;Khanna, D;Sawalha, AH;,
Arthritis & rheumatology
,PubMed ID 27482699
[NECTIN2]
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Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC200286 | PVRL2 (Myc-DDK-tagged)-Human poliovirus receptor-related 2 (herpesvirus entry mediator B) (PVRL2), transcript variant alpha. Note: ORF is codon optimized |
CNY 3,990.00 |
|
| RC200286L1 | Lenti-ORF clone of PVRL2 (Myc-DDK-tagged)-Human poliovirus receptor-related 2 (herpesvirus entry mediator B) (PVRL2), transcript variant alpha. Note: ORF is codon optimized |
CNY 5,890.00 |
|
| RC200286L2 | Lenti-ORF clone of PVRL2 (mGFP-tagged)-Human poliovirus receptor-related 2 (herpesvirus entry mediator B) (PVRL2), transcript variant alpha. Note: ORF is codon optimized |
CNY 5,890.00 |
|
| RC200286L3 | Lenti-ORF clone of PVRL2 (Myc-DDK-tagged)-Human poliovirus receptor-related 2 (herpesvirus entry mediator B) (PVRL2), transcript variant alpha. Note: ORF is codon optimized |
CNY 5,890.00 |
|
| RC200286L4 | Lenti-ORF clone of PVRL2 (mGFP-tagged)-Human poliovirus receptor-related 2 (herpesvirus entry mediator B) (PVRL2), transcript variant alpha. Note: ORF is codon optimized |
CNY 5,890.00 |
|
| RG200286 | PVRL2 (tGFP-tagged) - Human poliovirus receptor-related 2 (herpesvirus entry mediator B) (PVRL2), transcript variant alpha. Note: ORF is codon optimized |
CNY 4,370.00 |
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