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EPM2A (NM_005670) Human Untagged Clone
CAT＃: SC116585
EPM2A (untagged)-Human epilepsy, progressive myoclonus type 2A, Lafora disease (laforin) (EPM2A), transcript variant 1
CNY 2,400.00
CNY 2,950.00
Product images
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | EPM2; MELF |
| Vector | pCMV6-XL5 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data |
>NCBI ORF sequence for NM_005670, the custom clone sequence may differ by one or more nucleotides
ATGCGCTTCCGCTTTGGGGTGGTGGTGCCACCCGCCGTGGCCGGCGCCCGGCCGGAGCTGCTGGTGGTGG GGTCGCGGCCCGAGCTGGGGCGTTGGGAGCCGCGCGGTGCCGTCCGCCTGAGGCCGGCCGGCACCGCGGC GGGCGACGGGGCCCTGGCCCTGCAGGAGCCGGGCCTGTGGCTCGGGGAGGTGGAGCTGGCGGCCGAGGAG GCGGCGCAGGACGGGGCGGAGCCGGGCCGCGTGGACACGTTCTGGTACAAGTTCCTGAAGCGGGAGCCGG GAGGAGAGCTCTCCTGGGAAGGCAATGGACCTCATCATGACCGTTGCTGTACTTACAATGAAAACAACTT GGTGGATGGTGTGTATTGTCTCCCAATAGGACACTGGATTGAGGCCACTGGGCACACCAATGAAATGAAG CACACAACAGACTTCTATTTTAATATTGCAGGCCACCAAGCCATGCATTATTCAAGAATTCTACCAAATA TCTGGCTGGGTAGCTGCCCTCGTCAGGTGGAACATGTAACCATCAAACTGAAGCATGAATTGGGGATTAC AGCTGTAATGAATTTCCAGACTGAATGGGATATTGTACAGAATTCCTCAGGCTGTAACCGCTACCCAGAG CCCATGACTCCAGACACTATGATTAAACTATATAGGGAAGAAGGCTTGGCCTACATCTGGATGCCAACAC CAGATATGAGCACCGAAGGCCGAGTACAGATGCTGCCCCAGGCGGTGTGCCTGCTGCATGCGCTGCTGGA GAAGGGACACATCGTGTACGTGCACTGCAACGCTGGGGTGGGCCGCTCCACCGCGGCTGTCTGCGGCTGG CTCCAGTATGTGATGGGCTGGAATCTGAGGAAGGTGCAGTATTTCCTCATGGCCAAGAGGCCGGCTGTCT ACATTGACGAAGAGGCCTTGGCCCGGGCACAAGAAGATTTTTTCCAGAAATTTGGGAAGGTTCGTTCTTC TGTGTGTAGCCTGTAG >OriGene 5' read for NM_005670 unedited
GTAATACGACTCACTATAGGGCGGCCGCGAATTCGGCACGAGGCCTCGTGCCGAATTCGG CACGAGGGCTCGGGCCGCGCCTGCCGGCCGCGGGGACTCCGGGCCCGGGTATTCGCGCCG CCGCCGCCCGCCATGCGCTTCCGCTTTGGGGTGGTGGTGCCACCCGCCGTGGCCGGCGCC CGGCCGGAGCTGCTGGTGGTGGGGTCGCGGCCCGAGCTGGGGCGTTGGGACCGGCGGCGG GTGCCGTCCGCCTGAAGCCGGCCGGCACCGCGGCGGGCGACGGGGCCCTGGCGCTGCAAG AGCCGGGCCTGTGGCTCGGGGAGGTGGAGCTGGCGGCCGAGGAGGCGGCGCAGGACGGGG CGGAGCCGGGCCGCGTGGACACGTTCTGGTACAAGTTCCTGAAGCGGGAGCCGGGAGGAG AGCTCTCCTGGGAAGGCAATGGACCTCATCATGACCGTTGCTGTACTTACAATGAAAACA ACTTGGTGGATGGTGTGTATTGTCTCCCAATAGGACACTGGATTGAGGCCACTGGGCACA CCAATGAAATGAAGCACACAACAGACTTCTATTTTAATATTGCATGCCACCAAGCCATGC ATTATTCAAGAATTCTACCAAATATCTGGCTGGGTAACTGCCCTCGTCAGGTGGAACATG TAACCATCAAACTGAAGCATGAATTGGGGATTACAGCTGAAATGAATCTCCATATGAATG GGATATTGTACATAATCCCCCCAGCTGTAACCGCTACCCAAAGCCATGACTTCAGACCTA TGATCAAACTTATACGGAAAAAAGCTTTGCCACATCTGGATGCAAACCAGAATTAATACC CAGCCTACCCAAACCCGCCCATTAGGTGGCTACCCCACGCCCGGGGAAAAGAAAACCAGT ACCCCATGAAACTTCGCCAA >OriGene 3' read for NM_005670 unedited
GCCGCAATCTAAAGTCGAGTTTTTTTTTTTTTTTTTTCTTTTTAAATGCTTTTATTTGCC AAAAGTTTTGGGTGATTTTGAAATACATTAGACATCCCATTCATTGAGGAAAAAGACAGT TTATTCCAAAACATTCTTTAATAGTCCTAAACTGATTTTGTCTATCAGAGCAAAAGGAAC AAAGGTAAAAATCCACCTGAAAAAAGATCTTTGTATCATGGAAATTATGAAGCTGGATTT CTTAGACATTAAAGAAATTCACAGACCCACATAGTTTAAAAATTTAATTTTTAAGATTAA ATTTTCACAACACATTATGACTGTAAATGAGTTACCTGAATACCAATTATTACCTCTAGT TATTTTTAGCAAGGGAGCTGGACTTCACTTTACTTAATGCTAGCTTATAAATTTAACTTT GTAAAATTATAGTGGAAATGTGTCCTGGCTAGCTGCCTCTGCCCAAAGCAAATGTCATCT CCCCTAAGTGCCACAGTTCTATCTCCCCGTCCTCTGAGCTCCACTGAAACTTACCTTGTA TCCTTCTTGTCCCCCACGCCTTCTAAATAAGAGTCTCTTGCATCTATCAATATGTGTTTG TGGAAGAAAGGAAGGTGCAGAAAAATAAATACGCATCATAGTTTAATTAGGAAAGTAAGG GCTTTGAATCAAACCCAGCTTTGTATCTCACTTCATCTATTTATTCATCATGTGACAATA GACAGTTGAGTTAACCCTTCTGACCTTAGTTTCCCCATNCTTATCATGGAGATAATGAGA ACCTCTTCATTGGATATTNGAAGATTAAACTGGATATGATATATATCACCTTGCACATAG AGCTCTCATTAAAAAACACTCTCTTTCTTCATTTAGCATTCATTCATGGCCATCCTGCAT ACAGTGGTGATGCAGTCTGTNCTAGCACACATTTGAGCAAGTGTCTCTTGATTCCTGAAC TG |
| Restriction Sites | NotI-NotI |
| ACCN | NM_005670 |
| Insert Size | 3570 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Reference Data | |
| RefSeq | NM_005670.3, NP_005661.1 |
| RefSeq Size | 3474 bp |
| RefSeq ORF | 996 bp |
| Locus ID | 7957 |
| UniProt ID | O95278 |
| Domains | DSPc |
| Protein Families | Druggable Genome, Phosphatase |
| Gene Summary | This gene encodes a dual-specificity phosphatase and may be involved in the regulation of glycogen metabolism. The protein acts on complex carbohydrates to prevent glycogen hyperphosphorylation, thus avoiding the formation of insoluble aggregates. Loss-of-function mutations in this gene have been associated with Lafora disease, a rare, adult-onset recessive neurodegenerative disease, which results in myoclonus epilepsy and usually results in death several years after the onset of symptoms. The disease is characterized by the accumulation of insoluble particles called Lafora bodies, which are derived from glycogen. [provided by RefSeq, Jan 2018] Transcript Variant: This variant (1) represents the longest transcript, and encodes the longest isoform (a). Isoform a has been localized to the rough endoplasmic reticulum. |
Documents
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| FAQs |
| SDS |
Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC209743 | EPM2A (Myc-DDK-tagged)-Human epilepsy, progressive myoclonus type 2A, Lafora disease (laforin) (EPM2A), transcript variant 1 |
CNY 2,400.00 |
|
| RC209743L1 | Lenti ORF clone of Human epilepsy, progressive myoclonus type 2A, Lafora disease (laforin) (EPM2A), transcript variant 1, Myc-DDK-tagged |
CNY 4,800.00 |
|
| RC209743L2 | Lenti ORF clone of Human epilepsy, progressive myoclonus type 2A, Lafora disease (laforin) (EPM2A), transcript variant 1, mGFP tagged |
CNY 5,890.00 |
|
| RC209743L3 | Lenti ORF clone of Human epilepsy, progressive myoclonus type 2A, Lafora disease (laforin) (EPM2A), transcript variant 1, Myc-DDK-tagged |
CNY 5,890.00 |
|
| RC209743L4 | Lenti ORF clone of Human epilepsy, progressive myoclonus type 2A, Lafora disease (laforin) (EPM2A), transcript variant 1, mGFP tagged |
CNY 5,890.00 |
|
| RG209743 | EPM2A (tGFP-tagged) - Human epilepsy, progressive myoclonus type 2A, Lafora disease (laforin) (EPM2A), transcript variant 1 |
CNY 4,370.00 |
