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Diazepam Binding Inhibitor (DBI) (NM_020548) Human Untagged Clone
CAT＃: SC108851
DBI (untagged)-Human diazepam binding inhibitor (GABA receptor modulator, acyl-CoA binding protein) (DBI), transcript variant 1
CNY 1,200.00
CNY 2,950.00
| Cited in 2 publications. |
Product images
CNY 1,999.00
CNY 2,700.00
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | ACBD1; ACBP; CCK-RP; EP |
| Vector | pCMV6-XL5 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data |
>OriGene ORF within SC108851 sequence for NM_020548 edited (data generated by NextGen Sequencing)
ATGTGGGGCGACCTCTGGCTCCTCCCGCCTGCCTCTGCCAATCCGGGCACTGGGACAGAG GCTGAGTTTGAGAAAGCTGCAGAGGAGGTTAGGCACCTTAAGACCAAGCCATCGGATGAG GAGATGCTGTTCATCTATGGCCACTACAAACAAGCAACTGTGGGCGACATAAATACAGAA CGGCCCGGGATGTTGGACTTCACGGGCAAGGCCAAGTGGGATGCCTGGAATGAGCTGAAA GGGACTTCCAAGGAAGATGCCATGAAAGCTTACATCAACAAAGTAGAAGAGCTAAAGAAA AAATACGGGATATGA Clone variation with respect to NM_020548.6 >OriGene 5' read for NM_020548 unedited
AGAATTTTGTAATACGACTCACTATAGGGCGGCCCGCGATTCGGCACGAGGCTCAGTGTA GACCCTTGTCTGAGACCGAGCTATGTGGGGCGACCTCTGGCTCCTCCCGCCTGCCTCTGC CAATCCGGGCACTGGGACAGAGGCTGAGTTTGAGAAAGCTGCAGAGGAGGTTAGGCACCT TAAGACCAAGCCATCGGATGAGGAGATGCTGTTCATCTATGGCCACTACAAACAAGCAAC TGTGGGCGACATAAATACAGAACGGCCCGGGATGTTGGACTTCACGGGCAAGGCCAAGTG GGATGCCTGGAATGAGCTGAAAGGGACTTCCAAGGAAGATGCCATGAAAGCTTACATCAA CAAAGTAGAAGAGCTAAAGAAAAAATACGGGATATGAGAGACTGGATTTGGTTACTGTGC CATGTGTTTATCCTAAACTGAGACAATGCCTTGTTTTTTTCTAATACCGTGGATGGTGGG AATTCGGGAAAATAACCAGTTAAACCAGCTACTCAAGGCTGCTCACCATACGGCTCTAAC AGATTAGGGGCTAAAACGATTACTGACTTTCCTTGAGTAGTTTTTATCTGAAATCAATTA AAAGTGTATTTGTTACTTCAAAAAAAAAAAAAAAAACTCGACTCTAGATTGCGGCCGCGG TCATAGCTGTTTCCTGAACAGATCCCGGNTGGCATCCCTGTGACCCCTCCCCAGTGCCTC TCCTGGCCCTGGAAGTTGCCACTCCAGTGCCCACCAGCCTTGTCCTAATAAAATTAAGTG CATCATTTTGTCTGACTAGGTGTCCTTCTTAATATTATGGGTGGAAGGGGGTGGGATTTG GAACAGGGGCCAGTTGGGAAAACACCT >OriGene 3' read for NM_020548 unedited
CAATCTAGAGTCGAGTTTTTTTTTTTTTTTTTTGAAGTAACAAATACACTTTTAATTGAT TTCAGATAAAAACTACTCAAGGAAAGTCAGTAATCGTTTTAGCCCCTAATCTGTTAGAGC CGTATGGTGAGCAGCCTTGAGTAGCTGGTTTAACTGGTTATTTTCCCGAATTCCCACCAT CCACGGTATTAGAAAAAAACAAGGCATTGTCTCAGTTTAAGATAAACACATGGCACAGTA ACCAAATCCAGTCTCTCATATCCCGTATTTTTTCTTTAGCTCTTCTACTTTGTTGATGTA AGCTTTCATGGCATCTTCCTTGGAAGTCCCTTTCAGCTCATTCCAGGCATCCCACTTGGC CTTGCCCGTGAAGTCCAACATCCCGGGCCGTTCTGTATTTATGTCGCCCACAGTTGCTTG TTTGTAGTGGCCATAGATGAACAGCATCTCCTCATCCGATGGCTTGGTCTTAAAGTGCCT AACCTCCTCTGCAGCTTTCTCAAACTCAGCCTCTGTTCCCACTGCCCGGATTGGCACAAG CATCCGGCAAGACTCACACGTCCACCCCATACCCTCGGCCTAACCATGTCTTCACTGAAC CTCTCCCAATTCCCCGCCCCCCTTTATCGCTCCTCTTCCAATTTCTGCCGGTTTCCTAAC CATCTCTATTATATACTCCACTCCCCCCCCCTCCACCATGTTCTTTCCCTTCCTCGTTTC CCTTCCTCTCCCCCCAACCCCCTATATATCCTCTCTCTCATTCCTCCCCTCCTCACTTCT CTCTCCCCTCCTACTTTTGTTTCCCCTTACCCCTCCCACACCCTTCTTCTTCCACACCTA TCCTTTCCCCCCCTTCTCCCCCCCCTCCCCCTTTTCCCCCCCCCCCCCACCCTCCCTGCT ATATTTAATTCACCGCCAGACCACCAACCCCTACATTACACTCCACCTTCCTCTCACCTC TCCACACACCCCCCCN |
| Restriction Sites | NotI-NotI |
| ACCN | NM_020548 |
| Insert Size | 650 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Reference Data | |
| RefSeq | NM_020548.4, NP_065438.1 |
| RefSeq Size | 730 bp |
| RefSeq ORF | 315 bp |
| Locus ID | 1622 |
| UniProt ID | P07108 |
| Domains | ACBP |
| Protein Families | Druggable Genome |
| Protein Pathways | PPAR signaling pathway |
| Gene Summary | This gene encodes diazepam binding inhibitor, a protein that is regulated by hormones and is involved in lipid metabolism and the displacement of beta-carbolines and benzodiazepines, which modulate signal transduction at type A gamma-aminobutyric acid receptors located in brain synapses. The protein is conserved from yeast to mammals, with the most highly conserved domain consisting of seven contiguous residues that constitute the hydrophobic binding site for medium- and long-chain acyl-Coenzyme A esters. Diazepam binding inhibitor is also known to mediate the feedback regulation of pancreatic secretion and the postprandial release of cholecystokinin, in addition to its role as a mediator in corticotropin-dependent adrenal steroidogenesis. Three pseudogenes located on chromosomes 6, 8 and 16 have been identified. Multiple transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Jul 2008] Transcript Variant: This variant (1, also known as 1b) has an alternate splice site and an alternate exon in the 5' region, which results in an alternate translation start codon, as compared to variant 5. The resulting isoform (1) has a shorter and distinct N-terminus, compared to isoform 5. Variants 1, 7, 8, 9 and 10 encode the same isoform 1. |
Citations (2)
| The use of this cDNA Clones has been cited in the following citations: |
|---|
|
Targeting mitochondrial 18kDa Translocator protein (TSPO) regulates macrophage cholesterol efflux and lipid phenotype
,Taylor, JM;Allen, AM;Graham, A;,
Clin. Sci.
,PubMed ID 24814875
[DBI]
|
|
Anti-Argonaute RIP-Chip shows that miRNA transfections alter global patterns of mRNA recruitment to microribonucleoprotein complexes
,Wang-Xia Wang, Bernard R. Wilfred, Yanling Hu, Arnold J. Stromberg, and Peter T. Nelson,
RNA, Feb 2010; 16: 394 - 404
[DBI]
|
Documents
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Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC208982 | DBI (Myc-DDK-tagged)-Human diazepam binding inhibitor (GABA receptor modulator, acyl-CoA binding protein) (DBI), transcript variant 1 |
CNY 1,200.00 |
|
| RC208982L1 | Lenti ORF clone of Human diazepam binding inhibitor (GABA receptor modulator, acyl-CoA binding protein) (DBI), transcript variant 1, Myc-DDK-tagged |
CNY 3,600.00 |
|
| RC208982L2 | Lenti ORF clone of Human diazepam binding inhibitor (GABA receptor modulator, acyl-CoA binding protein) (DBI), transcript variant 1, mGFP tagged |
CNY 5,890.00 |
|
| RC208982L3 | Lenti ORF clone of Human diazepam binding inhibitor (GABA receptor modulator, acyl-CoA binding protein) (DBI), transcript variant 1, Myc-DDK-tagged |
CNY 5,890.00 |
|
| RC208982L4 | Lenti ORF clone of Human diazepam binding inhibitor (GABA receptor modulator, acyl-CoA binding protein) (DBI), transcript variant 1, mGFP tagged |
CNY 5,890.00 |
|
| RG208982 | DBI (tGFP-tagged) - Human diazepam binding inhibitor (GABA receptor modulator, acyl-CoA binding protein) (DBI), transcript variant 1 |
CNY 2,800.00 |
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