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P2Y12 (P2RY12) (NM_176876) Human Untagged Clone
CAT＃: SC106990
P2RY12 (untagged)-Human purinergic receptor P2Y, G-protein coupled, 12 (P2RY12), transcript variant 2
CNY 2,950.00
| Cited in 1 publication. |
Product images
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | ADPG-R; BDPLT8; HORK3; P2T(AC); P2Y(12)R; P2Y(AC); P2Y(ADP); P2Y(cyc); P2Y12; SP1999 |
| Vector | pCMV6-XL5 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data |
>NCBI ORF sequence for NM_176876, the custom clone sequence may differ by one or more nucleotides
ATGCAAGCCGTCGACAACCTCACCTCTGCGCCTGGTAACACCAGTCTGTGCACCAGAGACTACAAAATCA CCCAGGTCCTCTTCCCACTGCTCTACACTGTCCTGTTTTTTGTTGGACTTATCACAAATGGCCTGGCGAT GAGGATTTTCTTTCAAATCCGGAGTAAATCAAACTTTATTATTTTTCTTAAGAACACAGTCATTTCTGAT CTTCTCATGATTCTGACTTTTCCATTCAAAATTCTTAGTGATGCCAAACTGGGAACAGGACCACTGAGAA CTTTTGTGTGTCAAGTTACCTCCGTCATATTTTATTTCACAATGTATATCAGTATTTCATTCCTGGGACT GATAACTATCGATCGCTACCAGAAGACCACCAGGCCATTTAAAACATCCAACCCCAAAAATCTCTTGGGG GCTAAGATTCTCTCTGTTGTCATCTGGGCATTCATGTTCTTACTCTCTTTGCCTAACATGATTCTGACCA ACAGGCAGCCGAGAGACAAGAATGTGAAGAAATGCTCTTTCCTTAAATCAGAGTTCGGTCTAGTCTGGCA TGAAATAGTAAATTACATCTGTCAAGTCATTTTCTGGATTAATTTCTTAATTGTTATTGTATGTTATACA CTCATTACAAAAGAACTGTACCGGTCATACGTAAGAACGAGGGGTGTAGGTAAAGTCCCCAGGAAAAAGG TGAACGTCAAAGTTTTCATTATCATTGCTGTATTCTTTATTTGTTTTGTTCCTTTCCATTTTGCCCGAAT TCCTTACACCCTGAGCCAAACCCGGGATGTCTTTGACTGCACTGCTGAAAATACTCTGTTCTATGTGAAA GAGAGCACTCTGTGGTTAACTTCCTTAAATGCATGCCTGGATCCGTTCATCTATTTTTTCCTTTGCAAGT CCTTCAGAAATTCCTTGATAAGTATGCTGAAGTGCCCCAATTCTGCAACATCTCTGTCCCAGGACAATAG GAAAAAAGAACAGGATGGTGGTGACCCAAATGAAGAGACTCCAATGTAA >OriGene 5' read for NM_176876 unedited
CCCGTCAGAATTGTAAACGATCATATAGGCGGCCGCGAAATCGGCACGAGGGGCAGAACA GAACACTTTCTCATGTCCAGGGTCAGATTACAAGAGCACTCAAGACTTTACTGACGAAAA CTCAGGAAATCCTCTATCACAAAGAGGTTTGGCAACTAAACTAAGACATTAAAAGGAAAA TACCAGATGCCACTCTGCAGGCTGCAATAACTACTACTTACTGGATACATTCAAACCCTC CAGAATCAACAGTTATCAGGTAACCAACAAGAAATGCAAGCCGTCGACAACCTCACCTCT GCGCCTGGGAACACCAGTCTGTGCACCAGAGACTACAAAATCACCCAGGTCCTCTTCCCA CTGCTCTACACTGTCCTGTTTTTTGTTGGACTTATCACAAATGGCCTGGCGATGAGGATT TTCTTTCAAATCCGGAGTAAATCAAACTTTATTATTTTTCTTAAGAACACAGTCATTTCT GATCTTCTCATGAGTCTGACTTTTCCATTCAAAATTCTTAGTGATGCCAAACTGGGAACA GGACCACTGAGAACTTTTGTGTGTCAAGTTACCTCCGTCATATTTTATTTCACAATGTAT ATCAGTATTTCATTCCTGGGACTGATAACTATCGATCGCTACCAGAAGACCACCAGGCCA TTTAAAACATCCAACCCCAAAAATCTCTTGGGGGCTAAGAGTCTCTCTGTTGTCATCTGG GCATTCATGTTCTTACTCTCTTTGCCTAACATGACTCTGACCAACAGGCAGCCGAGAGAC AAGAATGTGAAGCAATGCTCTTTCCTTAAATCAGAGNTCGGTCTAGTCTGGCATGACATA GTAAAGTCCCCAGGAACAAGGTGCATGTCAAAGATTTCATTATCCATGCTGNAGTCTTAA TTGCTTTGTN >OriGene 3' read for NM_176876 unedited
TGGACCGCGGGCCGCAATCTAGAGTCGAGTTTTTTTTTTTTTTTTTTAGAGTTTAATGTA AATTTTGTATTTTATACACACCAATACAAACAAGTAATTACAAACAGATCAATCACTTTC CTCTCAGTAGTTATGCTGTGCAACTTTGTAATCATATTTAATTAATTTTTTTCACTAAGG TAAAATGTTCATTAACCTAATTAGCAGCTATTTTCTAGAAGCTAATTAATAAAGGTAAGT GTCAGTGATGGTATTATTGAAGTTGTAAAAAATTAGTAAAACTAGTTTCTCTAGAATTAA GGAAATATTTCTATATTTTTTAGTATTAGAATGTCATAAAAGTAAGTCTCCTTATTTTAA TGACTTCGATATTTCTTCTCTTTATTGTAAAGGTCTTCTTTAAATCTTTATCTTCTAAAT AAACATAAAAAATTAAGTCCAATCAAATACAGTTTCAATTAGTTTAAATCCCTTAGGTTT TTGCTAATAATGAAAAGTTAATAGTTATTATTCTTTGTGTATCCCACTTACTTAAATTTT TATAAGTATCCCAATAGGTCAGGATTTGGTTAGGGGACTAGGATATATATACATTTTAAC TATCATTTTTGGTAAGAAGATTATATCCAATTGATCGTTCTTCCTTAGTTGATTATGAAA AAATAAAATTGTGAACGATAATGTATTTTAAAAATTACAGTAAATATTATATGATTACTC ATTTTGGCAAAACTCTGCAAAACATGAATTCTGTGTAGTTTTGCATGCAGCATGACAATT GGATGTCGTTTGTTTTGCTGCTAATACAGCTACAGTNTAGATTAGTNTTCTATATTTTAA GATAGCTTNTCATACTGGAAAGGGTAATGANAANNTGCTTTNNGTATCTNCTGTNTCTTT AGAGNCATTATTATTAACTNAGNNTGCTCNTCGNCANTAAA |
| Restriction Sites | NotI-NotI |
| ACCN | NM_176876 |
| Insert Size | 2190 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Reference Data | |
| RefSeq | NM_176876.1, NP_795345.1 |
| RefSeq Size | 1474 bp |
| RefSeq ORF | 1029 bp |
| Locus ID | 64805 |
| UniProt ID | Q9H244 |
| Protein Families | Druggable Genome, GPCR, Transmembrane |
| Gene Summary | The product of this gene belongs to the family of G-protein coupled receptors. This family has several receptor subtypes with different pharmacological selectivity, which overlaps in some cases, for various adenosine and uridine nucleotides. This receptor is involved in platelet aggregation, and is a potential target for the treatment of thromboembolisms and other clotting disorders. Mutations in this gene are implicated in bleeding disorder, platelet type 8 (BDPLT8). Alternative splicing results in multiple transcript variants of this gene. [provided by RefSeq, Jul 2013] Transcript Variant: This variant (2) differs in the 5' UTR compared to variant 1. Variants 1 and 2 encode the same protein. |
Citations (1)
| The use of this cDNA Clones has been cited in the following citations: |
|---|
|
The active metabolite of Clopidogrel disrupts P2Y12 receptor oligomers and partitions them out of lipid rafts
,Pierre Savi, Jean-Luc Zachayus, Nathalie Delesque-Touchard, Catherine Labouret, Caroline Hervé, Marie-Françoise Uzabiaga, Jean-Marie Pereillo, Jean-Michel Culouscou, Françoise Bono, Pascual Ferrara, and Jean-Marc Herbert,
Proc Natl Acad Sci USA, Jul 2006; 103: 11069 - 11074.
[P2RY12]
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Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC213478 | P2RY12 (Myc-DDK-tagged)-Human purinergic receptor P2Y, G-protein coupled, 12 (P2RY12), transcript variant 2 |
CNY 3,656.00 |
|
| RC213478L1 | Lenti ORF clone of Human purinergic receptor P2Y, G-protein coupled, 12 (P2RY12), transcript variant 2, Myc-DDK-tagged |
CNY 5,890.00 |
|
| RC213478L2 | Lenti ORF clone of Human purinergic receptor P2Y, G-protein coupled, 12 (P2RY12), transcript variant 2, mGFP tagged |
CNY 5,890.00 |
|
| RC213478L3 | Lenti ORF clone of Human purinergic receptor P2Y, G-protein coupled, 12 (P2RY12), transcript variant 2, Myc-DDK-tagged |
CNY 5,890.00 |
|
| RC213478L4 | Lenti ORF clone of Human purinergic receptor P2Y, G-protein coupled, 12 (P2RY12), transcript variant 2, mGFP tagged |
CNY 5,890.00 |
|
| RG213478 | P2RY12 (tGFP-tagged) - Human purinergic receptor P2Y, G-protein coupled, 12 (P2RY12), transcript variant 2 |
CNY 4,370.00 |
