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MTR (NM_001291939) Human Tagged ORF Clone
CAT＃: RG240049
- TrueORF®
MTR (tGFP-tagged) - Human 5-methyltetrahydrofolate-homocysteine methyltransferase (MTR), transcript variant 2
ORF Plasmid: DDK
"NM_001291939" in other vectors (2)
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CNY 12,450.00
货期*
2周
规格
Product images
经常一起买 (5)
Specifications
| Product Data | |
| Tag | TurboGFP |
| Synonyms | cblG; HMAG; MS |
| Vector | pCMV6-AC-GFP |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | Neomycin |
| Sequence Data |
>RG240049 representing NM_001291939.
Blue=ORF Red=Cloning site Green=Tag(s) GCTCGTTTAGTGAACCGTCAGAATTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTG GATCCGGTACCGAGGAGATCTGCCGCCGCGATCGCC ATGTCACCCGCGCTCCAAGACCTGTCGCAACCCGAAGGTCTGAAGAAAACCCTGCGGGATGAGATCAAT GCCATTCTGCAGAAGAGGATTATGGTGCTGGATGGAGGGATGGGGACCATGATCCAGCGGGAGAAGCTA AACGAAGAACACTTCCGAGGTCAGGAATTTAAAGATCATGCCAGGCCGCTGAAAGGCAACAATGACATT TTAAGTATAACTCAGCCTGATGTCATTTACCAAATCCATAAGGAATACTTGCTGGCTGGGGCAGATATC ATTGAAACAAATACTTTTAGCAGCACTAGTATTGCCCAAGCTGACTATGGCCTTGAACACTTGGCCTAC CGGATGAACATGTGCTCTGCAGGAGTGGCCAGAAAAGCTGCCGAGGAGGTAACTCTCCAGACAGGAATT AAGAGGTTTGTGGCAGGGGCTCTGGGTCCGACTAATAAGACACTCTCTGTGTCCCCATCTGTGGAAAGG CCGGATTATAGGAACATCACATTTGATGAGCTTGTTGAAGCATACCAAGAGCAGGCCAAAGGACTTCTG GATGGCGGGGTTGATATCTTACTCATTGAAACTATTTTTGATACTGCCAATGCCAAGGCAGCCTTGTTT GCACTCCAAAATCTTTTTGAGGAGAAATATGCTCCCCGGCCTATCTTTATTTCAGGGACGATCGTTGAT AAAAGTGGGCGGACTCTTTCCGGACAGACAGGAGAGGGATTTGTCATCAGCGTGTCTCATGGAGAACCA CTCTGCATTGGATTAAATTGTGCTTTGGGTGCAGCTGAAATGAGACCTTTTATTGAAATAATTGGAAAA TGTACAACAGCCTATGTCCTCTGTTATCCCAATGCAGGTCTTCCCAACACCTTTGGTGACTATGATGAA ACGCCTTCTATGATGGCCAAGCACCTAAAGGATTTTGCTATGGATGGCTTGGTCAATATAGTTGGAGGA TGCTGTGGGTCAACACCAGATCATATCAGGGAAATTGCTGAAGCTGTGAAAAATTGTAAGCCTAGAGTT CCACCTGCCACTGCTTTTGAAGGACATATGTTACTGTCTGGTCTAGAGCCCTTCAGGATTGGACCGTAC ACCAACTTTGTTAACATTGGAGAGCGCTGTAATGTTGCAGGATCAAGGAAGTTTGCTAAACTCATCATG GCAGGAAACTATGAAGAAGCCTTGTGTGTTGCCAAAGTGCAGGTGGAAATGGGAGCCCAGGTGTTGGAT GTCAACATGGATGATGGCATGCTAGATGGTCCAAGTGCAATGACCAGATTTTGCAACTTAATTGCTTCC GAGCCAGACATCGCAAAGGTACCTTTGTGCATCGACTCCTCCAATTTTGCTGTGATTGAAGCTGGGTTA AAGTGCTGCCAAGGGAAGTGCATTGTCAATAGCATTAGTCTGAAGGAAGGAGAGGACGACTTCTTGGAG AAGGCCAGGAAGATTAAAAAGTATGGAGCTGCTATGGTGGTCATGGCTTTTGATGAAGAAGGACAGGCA ACAGAAACAGACACAAAAATCAGAGTGTGCACCCGGGCCTACCATCTGCTTGTGAAAAAACTGGGCTTT AATCCAAATGACATTATTTTTGACCCTAATATCCTAACCATTGGGACTGGAATGGAGGAACACAACTTG TATGCCATTAATTTTATCCATGCAACAAAAGTCATTAAAGAAACATTACCTGGAGCCAGAATAAGTGGA GGTCTTTCCAACTTGTCCTTCTCCTTCCGAGGAATGGAAGCCATTCGAGAAGCAATGCATGGGGTTTTC CTTTACCATGCAATCAAGTCTGGCATGGACATGGGGATAGTGAATGCTGGAAACCTCCCTGTGTATGAT GATATCCATAAGGAACTTCTGCAGCTCTGTGAAGATCTCATCTGGAATAAAGACCCTGAGGCCACTGAG AAGCTCTTACGTTATGCCCAGACTCAAGGCACAGGAGGGAAGAAAGTCATTCAGACTGATGAGTGGAGA AATGGCCCTGTCGAAGAACGCCTTGAGTATGCCCTTGTGAAGGTTATAAAGTCAGCCCGGGTTATGAAG AAGGCTGTTGGCCACCTTATCCCTTTCATGGAAAAAGAAAGAGAAGAAACCAGAGTGCTTAACGGCACA GTAGAAGAAGAGGACCCTTACCAGGGCACCATCGTGCTGGCCACTGTTAAAGGCGACGTGCACGACATA GGCAAGAACATAGTTGGAGTAGTCCTTGGCTGCAATAATTTCCGAGTTATTGATTTAGGAGTCATGACT CCATGTGATAAGATACTGAAAGCTGCTCTTGACCACAAAGCAGATATAATTGGCCTGTCAGGACTCATC ACTCCTTCCCTGGATGAAATGATTTTTGTTGCCAAGGAAATGGAGAGATTAGCTATAAGGATTCCATTG TTGATTGGAGGAGCAACCACTTCAAAAACCCACACAGCAGTTAAAATAGCTCCGAGATACAGTGCACCT GTAATCCATGTCCTGGACGCGTCCAAGAGTGTGGTGGTGTGTTCCCAGCTGTTAGATGAAAATCTAAAG GATGAATACTTTGAGGAAATCATGGAAGAATATGAAGATATTAGACAGGACCATTATGAGTCTCTCAAG GAGAGGAGATACTTACCCTTAAGTCAAGCCAGAAAAAGTGGTTTCCAAATGGATTGGCTGTCTGAACCT CACCCAGTGAAGCCCACGTTTATTGGGACCCAGGTCTTTGAAGACTATGACCTGCAGAAGCTGGTGGAC TACATTGACTGGAAGCCTTTCTTTGATGTCTGGCAGCTCCGGGGCAAGTACCCGAATCGAGGCTTTCCC AAGATATTTAACGACAAAACAGTAGGTGGAGAGGCCAGGAAGGTCTACGATGATGCCCACAATATGCTG AACACACTGATTAGTCAAAAGAAACTCCGGGCCCGGGGTGTGGTTGGGTTCTGGCCAGCACAGAGTATC CAAGACGACATTCACCTGTACGCAGAGGCTGCTGTGCCCCAGGCTGCAGAGCCCATAGCCACCTTCTAT GGGTTAAGGCAACAGGCTGAGAAGGACTCTGCCAGCACGGAGCCATACTACTGCCTCTCAGACTTCATC GCTCCCTTGCATTCTGGCATCCGTGACTACCTGGGCCTGTTTGCCGTTGCCTGCTTTGGGGTAGAAGAG CTGAGCAAGGCCTATGAGGATGATGGTGACGACTACAGCAGCATCATGGTCAAGGCGCTGGGGGACCGG CTGGCAGAGGCCTTTGCAGAAGAGCTCCATGAAAGAGTTCGCCGAGAACTGTGGGCCTACTGTGGCAGT GAGCAGCTGGACGTCGCAGACCTGCGCAGGCTGCGGTACAAGGGCATCCGCCCGGCTCCTGGCTACCCC AGCCAGCCCGACCACACCGAGAAGCTCACCATGTGGAGACTCGCAGACATCGAGCAGTCTACAGGCATT AGGTTAACAGAATCATTAGCAATGGCACCTGCTTCAGCAGTCTCAGGCCTCTACTTCTCCAATTTGAAG TCCAAATATTTTGCTGTGGGGAAGATTTCCAAGGATCAGGTTGAGGATTATGCATTGAGGAAGAACATA TCTGTGGCTGAGGTTGAGAAATGGCTTGGACCCATTTTGGGATATGATACAGAC AGCGGACCGACGCGTACGCGGCCGCTCGAG - GFP Tag - GTTTAAAC >Peptide sequence encoded by RG240049
Blue=ORF Red=Cloning site Green=Tag(s) MSPALQDLSQPEGLKKTLRDEINAILQKRIMVLDGGMGTMIQREKLNEEHFRGQEFKDHARPLKGNNDI LSITQPDVIYQIHKEYLLAGADIIETNTFSSTSIAQADYGLEHLAYRMNMCSAGVARKAAEEVTLQTGI KRFVAGALGPTNKTLSVSPSVERPDYRNITFDELVEAYQEQAKGLLDGGVDILLIETIFDTANAKAALF ALQNLFEEKYAPRPIFISGTIVDKSGRTLSGQTGEGFVISVSHGEPLCIGLNCALGAAEMRPFIEIIGK CTTAYVLCYPNAGLPNTFGDYDETPSMMAKHLKDFAMDGLVNIVGGCCGSTPDHIREIAEAVKNCKPRV PPATAFEGHMLLSGLEPFRIGPYTNFVNIGERCNVAGSRKFAKLIMAGNYEEALCVAKVQVEMGAQVLD VNMDDGMLDGPSAMTRFCNLIASEPDIAKVPLCIDSSNFAVIEAGLKCCQGKCIVNSISLKEGEDDFLE KARKIKKYGAAMVVMAFDEEGQATETDTKIRVCTRAYHLLVKKLGFNPNDIIFDPNILTIGTGMEEHNL YAINFIHATKVIKETLPGARISGGLSNLSFSFRGMEAIREAMHGVFLYHAIKSGMDMGIVNAGNLPVYD DIHKELLQLCEDLIWNKDPEATEKLLRYAQTQGTGGKKVIQTDEWRNGPVEERLEYALVKVIKSARVMK KAVGHLIPFMEKEREETRVLNGTVEEEDPYQGTIVLATVKGDVHDIGKNIVGVVLGCNNFRVIDLGVMT PCDKILKAALDHKADIIGLSGLITPSLDEMIFVAKEMERLAIRIPLLIGGATTSKTHTAVKIAPRYSAP VIHVLDASKSVVVCSQLLDENLKDEYFEEIMEEYEDIRQDHYESLKERRYLPLSQARKSGFQMDWLSEP HPVKPTFIGTQVFEDYDLQKLVDYIDWKPFFDVWQLRGKYPNRGFPKIFNDKTVGGEARKVYDDAHNML NTLISQKKLRARGVVGFWPAQSIQDDIHLYAEAAVPQAAEPIATFYGLRQQAEKDSASTEPYYCLSDFI APLHSGIRDYLGLFAVACFGVEELSKAYEDDGDDYSSIMVKALGDRLAEAFAEELHERVRRELWAYCGS EQLDVADLRRLRYKGIRPAPGYPSQPDHTEKLTMWRLADIEQSTGIRLTESLAMAPASAVSGLYFSNLK SKYFAVGKISKDQVEDYALRKNISVAEVEKWLGPILGYDTD SGPTRTRPLEMESDESGLPAMEIECRITGTLNGVEFELVGGGEGTPEQGRMTNKMKSTKGALTFSPYLL SHVMGYGFYHFGTYPSGYENPFLHAINNGGYTNTRIEKYEDGGVLHVSFSYRYEAGRVIGDFKVMGTGF PEDSVIFTDKIIRSNATVEHLHPMGDNDLDGSFTRTFSLRDGGYYSSVVDSHMHFKSAIHPSILQNGGP MFAFRRVEEDHSNTELGIVEYQHAFKTPDADAGEERV |
| Restriction Sites |
SgfI-RsrII
Cloning Scheme for this gene
Plasmid Map
|
| ACCN | NM_001291939 |
| ORF Size | 3642 bp |
| OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reference Data | |
| RefSeq | NM_001291939.1, NP_001278868.1 |
| RefSeq Size | 10422 bp |
| RefSeq ORF | 3645 bp |
| Locus ID | 4548 |
| UniProt ID | Q99707 |
| Protein Families | Druggable Genome |
| Protein Pathways | Cysteine and methionine metabolism, Metabolic pathways, One carbon pool by folate |
| MW | 135.2 kDa |
| Gene Summary | This gene encodes the 5-methyltetrahydrofolate-homocysteine methyltransferase. This enzyme, also known as cobalamin-dependent methionine synthase, catalyzes the final step in methionine biosynthesis. Mutations in MTR have been identified as the underlying cause of methylcobalamin deficiency complementation group G. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, May 2014] |
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