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CMKLR1 (NM_004072) Human Tagged ORF Clone
CAT＃: RC217247
CMKLR1 (Myc-DDK-tagged)-Human chemokine-like receptor 1 (CMKLR1), transcript variant 2
ORF Plasmid: tGFP
"NM_004072" in other vectors (6)
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CNY 3,656.00
CNY 4,370.00
Product images
CNY 300.00
Specifications
| Product Data | |
| Type | Human Tagged ORF Clone |
| Tag | Myc-DDK |
| Synonyms | CHEMERINR; ChemR23; DEZ; RVER1 |
| Vector | pCMV6-Entry |
| E. coli Selection | Kanamycin (25 ug/mL) |
| Mammalian Cell Selection | Neomycin |
| Sequence Data |
>RC217247 representing NM_004072
Red=Cloning site Blue=ORF Green=Tags(s) TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC GCCGCGATCGCC ATGGAGGATGAAGATTACAACACTTCCATCAGTTACGGTGATGAATACCCTGATTATTTAGACTCCATTG TGGTTTTGGAGGACTTATCCCCCTTGGAAGCCAGGGTGACCAGGATCTTCCTGGTGGTGGTCTACAGCAT CGTCTGCTTCCTCGGGATTCTGGGCAATGGTCTGGTGATCATCATTGCCACCTTCAAGATGAAGAAGACA GTGAACATGGTCTGGTTCCTCAACCTGGCAGTGGCAGATTTCCTGTTCAACGTCTTCCTCCCAATCCATA TCACCTATGCCGCCATGGACTACCACTGGGTTTTCGGGACAGCCATGTGCAAGATCAGCAACTTCCTTCT CATCCACAACATGTTCACCAGCGTCTTCCTGCTGACCATCATCAGCTCTGACCGCTGCATCTCTGTGCTC CTCCCTGTCTGGTCCCAGAACCACCGCAGCGTTCGCCTGGCTTACATGGCCTGCATGGTCATCTGGGTCC TGGCTTTCTTCTTGAGTTCCCCATCTCTCGTCTTCCGGGACACAGCCAACCTGCATGGGAAAATATCCTG CTTCAACAACTTCAGCCTGTCCACACCTGGGTCTTCCTCGTGGCCCACTCACTCCCAAATGGACCCTGTG GGGTATAGCCGGCACATGGTGGTGACTGTCACCCGCTTCCTCTGTGGCTTCCTGGTCCCAGTCCTCATCA TCACAGCTTGCTACCTCACCATCGTGTGCAAACTGCAGCGCAACCGCCTGGCCAAGACCAAGAAGCCCTT CAAGATTATTGTGACCATCATCATTACCTTCTTCCTCTGCTGGTGCCCCTACCACACACTCAACCTCCTA GAGCTCCACCACACTGCCATGCCTGGCTCTGTCTTCAGCCTGGGTTTGCCCCTGGCCACTGCCCTTGCCA TTGCCAACAGCTGCATGAACCCCATTCTGTATGTTTTCATGGGTCAGGACTTCAAGAAGTTCAAGGTGGC CCTCTTCTCTCGCCTGGTCAATGCTCTAAGTGAAGATACAGGCCACTCTTCCTACCCCAGCCATAGAAGC TTTACCAAGATGTCATCAATGAATGAGAGGACTTCTATGAATGAGAGGGAGACCGGCATGCTT ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGATT ACAAGGATGACGACGATAAGGTTTAA >RC217247 representing NM_004072
Red=Cloning site Green=Tags(s) MEDEDYNTSISYGDEYPDYLDSIVVLEDLSPLEARVTRIFLVVVYSIVCFLGILGNGLVIIIATFKMKKT VNMVWFLNLAVADFLFNVFLPIHITYAAMDYHWVFGTAMCKISNFLLIHNMFTSVFLLTIISSDRCISVL LPVWSQNHRSVRLAYMACMVIWVLAFFLSSPSLVFRDTANLHGKISCFNNFSLSTPGSSSWPTHSQMDPV GYSRHMVVTVTRFLCGFLVPVLIITACYLTIVCKLQRNRLAKTKKPFKIIVTIIITFFLCWCPYHTLNLL ELHHTAMPGSVFSLGLPLATALAIANSCMNPILYVFMGQDFKKFKVALFSRLVNALSEDTGHSSYPSHRS FTKMSSMNERTSMNERETGML TRTRPLEQKLISEEDLAANDILDYKDDDDKV |
| Chromatograms |
CHROMATOGRAMS
 Sequencher program is needed, download here. |
| Restriction Sites |
SgfI-MluI
Cloning Scheme for this gene
Plasmid Map
|
| ACCN | NM_004072 |
| ORF Size | 1113 bp |
| OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Reference Data | |
| RefSeq | NM_004072.3 |
| RefSeq Size | 1900 bp |
| RefSeq ORF | 1116 bp |
| Locus ID | 1240 |
| UniProt ID | Q99788 |
| Domains | 7tm_1 |
| Protein Families | Druggable Genome, GPCR, Transmembrane |
| MW | 41.9 kDa |
| Gene Summary | Receptor for the chemoattractant adipokine chemerin/RARRES2 and for the omega-3 fatty acid derived molecule resolvin E1. Interaction with RARRES2 induces activation of intracellular signaling molecules, such as SKY, MAPK1/3 (ERK1/2), MAPK14/P38MAPK and PI3K leading to multifunctional effects, like, reduction of immune responses, enhancing of adipogenesis and angionesis. Resolvin E1 down-regulates cytokine production in macrophages by reducing the activation of MAPK1/3 (ERK1/2) and NF-kappa-B. Positively regulates adipogenesis and adipocyte metabolism. Acts as a coreceptor for several SIV strains (SIVMAC316, SIVMAC239, SIVMACL7E-FR and SIVSM62A), as well as a primary HIV-1 strain (92UG024-2).[UniProtKB/Swiss-Prot Function] |
Documents
| Product Manuals |
| FAQs |
| SDS |
Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC217247L1 | Lenti ORF clone of Human chemokine-like receptor 1 (CMKLR1), transcript variant 2, Myc-DDK-tagged |
CNY 5,890.00 |
|
| RC217247L2 | Lenti ORF clone of Human chemokine-like receptor 1 (CMKLR1), transcript variant 2, mGFP tagged |
CNY 5,890.00 |
|
| RC217247L3 | Lenti ORF clone of Human chemokine-like receptor 1 (CMKLR1), transcript variant 2, Myc-DDK-tagged |
CNY 5,890.00 |
|
| RC217247L4 | Lenti ORF clone of Human chemokine-like receptor 1 (CMKLR1), transcript variant 2, mGFP tagged |
CNY 5,890.00 |
|
| RG217247 | CMKLR1 (tGFP-tagged) - Human chemokine-like receptor 1 (CMKLR1), transcript variant 2 |
CNY 4,370.00 |
|
| SC117575 | CMKLR1 (untagged)-Human chemokine-like receptor 1 (CMKLR1), transcript variant 2 |
CNY 3,656.00 |
