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COMMD5 (NM_001081003) Human Tagged ORF Clone
CAT＃: RC216768
COMMD5 (Myc-DDK-tagged)-Human COMM domain containing 5 (COMMD5), transcript variant 2
ORF Plasmid: tGFP
"NM_001081003" in other vectors (4)
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CNY 2,400.00
CNY 3,705.00
Product images
CNY 300.00
Specifications
| Product Data | |
| Type | Human Tagged ORF Clone |
| Tag | Myc-DDK |
| Synonyms | HCARG; HT002 |
| Vector | pCMV6-Entry |
| E. coli Selection | Kanamycin (25 ug/mL) |
| Mammalian Cell Selection | Neomycin |
| Sequence Data |
>RC216768 ORF sequence
Red=Cloning site Blue=ORF Green=Tags(s) TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC GCCGCGATCGCC ATGTCTGCTGTGGGGGCTGCAACTCCATACCTGCATCATCCTGGTGATAGTCACAGTGGCCGAGTGAGTT TCTTGGGGGCCCAGCTTCCTCCAGAGGTGGCAGCAATGGCCCGGCTACTAGGGGACCTAGACAGGAGCAC GTTCAGAAAGTTGCTGAAGTTTGTGGTCAGCAGCCTGCAGGGGGAGGACTGCCGAGAGGCTGTGCAGCGT CTTGGGGTCAGCGCCAACCTGCCGGAGGAGCAGCTGGGTGCCCTGCTGGCAGGCATGCACACACTGCTCC AGCAGGCCCTCCGTCTGCCCCCCACCAGCCTGAAGCCTGACACCTTCAGGGACCAGCTCCAGGAGCTCTG CATCCCCCAAGACCTGGTCGGGGACTTGGCCAGCGTGGTATTTGGGAGCCAGCGGCCCCTCCTTGATTCT GTGGCCCAGCAGCAGGGGGCCTGGCTGCCGCATGTTGCTGACTTTCGGTGGCGGGTGGATGTAGCAATCT CCACCAGTGCCCTGGCTCGCTCCCTGCAGCCGAGCGTCCTGATGCAGCTGAAGCTTTCAGATGGGTCAGC ATACCGCTTTGAGGTCCCCACAGCCAAGTTCCAGGAGCTGCGGTACAGCGTGGCCCTGGTCCTAAAGGAG ATGGCAGATCTGGAGAAGAGGTGTGAGCGCAGACTGCAGGAC ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGATT ACAAGGATGACGACGATAAGGTTTAA >RC216768 protein sequence
Red=Cloning site Green=Tags(s) MSAVGAATPYLHHPGDSHSGRVSFLGAQLPPEVAAMARLLGDLDRSTFRKLLKFVVSSLQGEDCREAVQR LGVSANLPEEQLGALLAGMHTLLQQALRLPPTSLKPDTFRDQLQELCIPQDLVGDLASVVFGSQRPLLDS VAQQQGAWLPHVADFRWRVDVAISTSALARSLQPSVLMQLKLSDGSAYRFEVPTAKFQELRYSVALVLKE MADLEKRCERRLQD TRTRPLEQKLISEEDLAANDILDYKDDDDKV |
| Chromatograms |
CHROMATOGRAMS
 Sequencher program is needed, download here. |
| Restriction Sites |
SgfI-MluI
Cloning Scheme for this gene
Plasmid Map
|
| ACCN | NM_001081003 |
| ORF Size | 672 bp |
| OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Reference Data | |
| RefSeq | NM_001081003.3 |
| RefSeq Size | 1453 bp |
| RefSeq ORF | 675 bp |
| Locus ID | 28991 |
| UniProt ID | Q9GZQ3 |
| Protein Families | Druggable Genome |
| MW | 24.7 kDa |
| Gene Summary | May modulate activity of cullin-RING E3 ubiquitin ligase (CRL) complexes (PubMed:21778237). Negatively regulates cell proliferation. Negatively regulates cell cycle G2/M phase transition probably by transactivating p21/CDKN1A through the p53/TP53-independent signaling pathway. Involved in kidney proximal tubule morphogenesis (By similarity). Down-regulates activation of NF-kappa-B (PubMed:15799966).[UniProtKB/Swiss-Prot Function] |
Documents
| Product Manuals |
| FAQs |
| SDS |
Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC216768L3 | Lenti ORF clone of Human COMM domain containing 5 (COMMD5), transcript variant 2, Myc-DDK-tagged |
CNY 5,890.00 |
|
| RC216768L4 | Lenti ORF clone of Human COMM domain containing 5 (COMMD5), transcript variant 2, mGFP tagged |
CNY 5,890.00 |
|
| RG216768 | COMMD5 (tGFP-tagged) - Human COMM domain containing 5 (COMMD5), transcript variant 2 |
CNY 4,370.00 |
|
| SC316686 | COMMD5 (untagged)-Human COMM domain containing 5 (COMMD5), transcript variant 2 |
CNY 3,990.00 |
