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NCOA62 (SNW1) (NM_012245) Human Tagged ORF Clone
CAT＃: RC215046
SNW1 (Myc-DDK-tagged)-Human SNW domain containing 1 (SNW1)
ORF Plasmid: tGFP
"NM_012245" in other vectors (6)
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CNY 3,990.00
Product images
CNY 300.00
Specifications
| Product Data | |
| Type | Human Tagged ORF Clone |
| Tag | Myc-DDK |
| Synonyms | Bx42; FUN20; NCOA-62; Prp45; PRPF45; SKIIP; SKIP; SKIP1 |
| Vector | pCMV6-Entry |
| E. coli Selection | Kanamycin (25 ug/mL) |
| Mammalian Cell Selection | Neomycin |
| Sequence Data |
>RC215046 representing NM_012245
Red=Cloning site Blue=ORF Green=Tags(s) TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC GCCGCGATCGCC ATGGCGCTCACCAGCTTTTTACCTGCACCTACTCAGCTATCTCAGGACCAGCTTGAGGCTGAAGAAAAGG CAAGATCCCAGAGATCACGGCAGACCTCACTGGTCTCCTCCCGAAGAGAACCTCCCCCGTACGGATACCG GAAAGGCTGGATACCTCGGTTATTAGAGGATTTTGGAGATGGAGGTGCTTTTCCAGAGATCCATGTGGCC CAGTATCCACTGGATATGGGACGAAAGAAAAAAATGTCGAATGCGCTGGCCATTCAGGTGGATTCTGAAG GAAAAATTAAATATGATGCAATTGCTCGACAAGGACAGTCAAAAGACAAGGTCATTTATAGCAAATACAC TGACCTGGTTCCAAAGGAGGTTATGAATGCAGATGATCCAGACCTGCAAAGGCCCGATGAAGAAGCTATT AAAGAGATAACAGAAAAGACAAGAGTAGCCTTAGAAAAATCTGTATCACAGAAGGTCGCCGCAGCCATGC CAGTTCGAGCAGCTGACAAATTGGCTCCTGCTCAGTATATCCGATACACACCATCTCAGCAAGGAGTGGC ATTCAACTCTGGAGCTAAACAGAGGGTTATTCGGATGGTAGAAATGCAGAAAGATCCAATGGAGCCTCCA AGGTTCAAGATTAATAAGAAAATTCCCCGGGGACCACCTTCTCCTCCTGCGCCTGTCATGCATTCTCCTA GCCGAAAGATGACTGTAAAGGAACAACAAGAGTGGAAGATTCCTCCTTGTATTTCTAACTGGAAAAATGC AAAGGGTTATACAATTCCATTAGACAAACGTCTGGCTGCTGATGGAAGAGGACTACAGACAGTACACATA AATGAAAATTTCGCCAAATTGGCAGAAGCCCTCTACATTGCTGATCGGAAGGCTCGTGAAGCTGTGGAAA TGCGTGCCCAAGTAGAGAGAAAAATGGCTCAGAAAGAAAAGGAAAAACATGAAGAGAAACTTAGAGAAAT GGCCCAGAAAGCCAGGGAAAGAAGAGCTGGGATCAAAACTCATGTGGAAAAAGAGGATGGGGAGGCACGT GAGAGGGATGAAATCCGGCATGACAGGCGAAAAGAGAGACAGCATGACCGGAATCTTTCCAGGGCAGCTC CTGATAAGAGGTCGAAACTTCAGAGAAATGAAAATCGGGATATCAGTGAAGTTATTGCTCTCGGTGTTCC TAATCCTCGGACTTCCAATGAAGTTCAGTATGACCAAAGGCTCTTCAACCAATCCAAGGGTATGGACAGT GGATTTGCAGGTGGAGAAGATGAAATTTATAATGTTTATGATCAAGCCTGGAGAGGTGGTAAAGATATGG CCCAGAGTATTTATAGGCCCAGTAAAAATCTGGACAAGGACATGTATGGTGATGACCTAGAAGCCAGAAT AAAGACCAACAGATTTGTTCCCGACAAGGAGTTTTCTGGTTCAGACCGTAGACAGAGAGGCCGAGAAGGA CCAGTTCAGTTTGAGGAAGATCCTTTTGGTTTGGACAAGTTTTTGGAAGAAGCCAAACAGCATGGTGGCT CTAAAAGACCCTCAGATAGCAGCCGCCCCAAGGAACACGAGCATGAAGGCAAGAAGAGGAGGAAGGAA ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGATT ACAAGGATGACGACGATAAGGTTTAA >RC215046 representing NM_012245
Red=Cloning site Green=Tags(s) MALTSFLPAPTQLSQDQLEAEEKARSQRSRQTSLVSSRREPPPYGYRKGWIPRLLEDFGDGGAFPEIHVA QYPLDMGRKKKMSNALAIQVDSEGKIKYDAIARQGQSKDKVIYSKYTDLVPKEVMNADDPDLQRPDEEAI KEITEKTRVALEKSVSQKVAAAMPVRAADKLAPAQYIRYTPSQQGVAFNSGAKQRVIRMVEMQKDPMEPP RFKINKKIPRGPPSPPAPVMHSPSRKMTVKEQQEWKIPPCISNWKNAKGYTIPLDKRLAADGRGLQTVHI NENFAKLAEALYIADRKAREAVEMRAQVERKMAQKEKEKHEEKLREMAQKARERRAGIKTHVEKEDGEAR ERDEIRHDRRKERQHDRNLSRAAPDKRSKLQRNENRDISEVIALGVPNPRTSNEVQYDQRLFNQSKGMDS GFAGGEDEIYNVYDQAWRGGKDMAQSIYRPSKNLDKDMYGDDLEARIKTNRFVPDKEFSGSDRRQRGREG PVQFEEDPFGLDKFLEEAKQHGGSKRPSDSSRPKEHEHEGKKRRKE TRTRPLEQKLISEEDLAANDILDYKDDDDKV |
| Chromatograms |
CHROMATOGRAMS
 Sequencher program is needed, download here. |
| Restriction Sites |
SgfI-MluI
Cloning Scheme for this gene
Plasmid Map
|
| ACCN | NM_012245 |
| ORF Size | 1608 bp |
| OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Reference Data | |
| RefSeq | NM_012245.3 |
| RefSeq Size | 2146 bp |
| RefSeq ORF | 1611 bp |
| Locus ID | 22938 |
| UniProt ID | Q13573 |
| Domains | SKIP_SNW |
| Protein Families | Druggable Genome, Transcription Factors |
| Protein Pathways | Notch signaling pathway, Spliceosome |
| MW | 61.3 kDa |
| Gene Summary | This gene, a member of the SNW gene family, encodes a coactivator that enhances transcription from some Pol II promoters. This coactivator can bind to the ligand-binding domain of the vitamin D receptor and to retinoid receptors to enhance vitamin D-, retinoic acid-, estrogen-, and glucocorticoid-mediated gene expression. It can also function as a splicing factor by interacting with poly(A)-binding protein 2 to directly control the expression of muscle-specific genes at the transcriptional level. Finally, the protein may be involved in oncogenesis since it interacts with a region of SKI oncoproteins that is required for transforming activity. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2016] |
Documents
| Product Manuals |
| FAQs |
| SDS |
Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC215046L1 | Lenti ORF clone of Human SNW domain containing 1 (SNW1), Myc-DDK-tagged |
CNY 5,890.00 |
|
| RC215046L2 | Lenti ORF clone of Human SNW domain containing 1 (SNW1), mGFP tagged |
CNY 5,890.00 |
|
| RC215046L3 | Lenti ORF clone of Human SNW domain containing 1 (SNW1), Myc-DDK-tagged |
CNY 5,890.00 |
|
| RC215046L4 | Lenti ORF clone of Human SNW domain containing 1 (SNW1), mGFP tagged |
CNY 5,890.00 |
|
| RG215046 | SNW1 (tGFP-tagged) - Human SNW domain containing 1 (SNW1) |
CNY 4,370.00 |
|
| SC115506 | SNW1 (untagged)-Human SNW domain containing 1 (SNW1) |
CNY 4,000.00 |
