Neuropilin 1 (NRP1) (NM_001024628) Human Tagged Lenti ORF Clone

CAT#: RC203508L1

  • LentiORF®

Lenti ORF clone of Human neuropilin 1 (NRP1), transcript variant 2, Myc-DDK-tagged



  "NM_001024628" in other vectors (6)

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CNY 5,890.00


货期*
现货

规格
    • 10 ug

Product images

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Lenti-vpak packaging kit - packaging plasmids and transfection reagent
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Reverse primer to sequence targets cloned in expression vectors.
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Neuropilin-1 (NRP1) Rabbit polyclonal Antibody
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Specifications

Product Data
Type Human Tagged ORF Clone
Tag Myc-DDK
Synonyms BDCA4; CD304; NP1; NRP; VEGF165R
Vector pLenti-C-Myc-DDK
E. coli Selection Chloramphenicol (34 ug/mL)
Mammalian Cell Selection None
Sequence Data
The ORF insert of this clone is exactly the same as(RC203508).
Restriction Sites SgfI-MluI      Cloning Scheme for this gene      Plasmid Map     
ACCN NM_001024628
ORF Size 1932 bp
OTI Disclaimer The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
OTI Annotation This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.
Product Components The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
Reconstitution 1. Centrifuge at 5,000xg for 5min.
2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
3. Close the tube and incubate for 10 minutes at room temperature.
4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.
Reference Data
RefSeq NM_001024628.1
RefSeq Size 2478 bp
RefSeq ORF 1935 bp
Locus ID 8829
UniProt ID O14786
Protein Families Druggable Genome, Secreted Protein, Transmembrane
Protein Pathways Axon guidance
MW 71.9 kDa
Gene Summary This gene encodes one of two neuropilins, which contain specific protein domains which allow them to participate in several different types of signaling pathways that control cell migration. Neuropilins contain a large N-terminal extracellular domain, made up of complement-binding, coagulation factor V/VIII, and meprin domains. These proteins also contains a short membrane-spanning domain and a small cytoplasmic domain. Neuropilins bind many ligands and various types of co-receptors; they affect cell survival, migration, and attraction. Some of the ligands and co-receptors bound by neuropilins are vascular endothelial growth factor (VEGF) and semaphorin family members. This protein has also been determined to act as a co-receptor for SARS-CoV-2 (which causes COVID-19) to infect host cells. [provided by RefSeq, Nov 2020]
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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