United States
Germany
Japan
United Kingdom
China
Stra6 (NM_001162476) Mouse Tagged ORF Clone
CAT＃: MR216996
- TrueORF®
Stra6 (Myc-DDK-tagged) - Mouse stimulated by retinoic acid gene 6 (Stra6), transcript variant 1
ORF Plasmid: tGFP
"NM_001162476" in other vectors (3)
Need custom modification / cloning service?
Get a free quote
CNY 4,912.00
CNY 5,800.00
Product images
CNY 300.00
Specifications
| Product Data | |
| Type | Mouse Tagged ORF Clone |
| Tag | Myc-DDK |
| Synonyms | AI891933 |
| Vector | pCMV6-Entry |
| E. coli Selection | Kanamycin (25 ug/mL) |
| Mammalian Cell Selection | Neomycin |
| Sequence Data |
>MR216996 representing NM_001162476
Red=Cloning site Blue=ORF Green=Tags(s) TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC GCCGCGATCGCC ATGGAGTCCCAGGCATCTGAGAATGGAAGCCAGACCTCCTCCGGGGTGACAGATGACTACAGCAGCTGGT ACATCGAGGAACCTCTAGGAGCTGAGGAGGTGCAGCCAGAGGGGGTGATTCCCCTTTGCCAGCTCACCGC ACCCCCTGCCCTGCTCCATGCCTGCCTGGCTTCACTGTCGTTCCTGGTTCTGCTGCTGCTGGCCTTGCTG GTGAGACGGCGCAGGCTTTGGCCACGCTGTGGTCATCGCGGACTTGGACTGCCCAGCCCTGTGGATTTCT TGGCTGGGGACCTATCCTGGACAGTGCCTGCTGCTGTCTTTGTGGTCCTCTTCAGCAACCTATGCCTGTT GCTCCCTGATGAGAACCCACTGCCTTTCCTGAACCTCACTGCAGCATCAAGTCCAGATGGAGAGATGGAG ACATCAAGAGGGCCCTGGAAGCTACTGGCTCTGCTCTACTATCCAGCCCTCTATTACCCTCTGGCTGCTT GTGCTTCGGCAGGGCACCAAGCTGCATTCCTATTGGGTACTGTGTTATCTTGGGCCCACTTTGGTGTTCA GGTCTGGCAGAAAGCTGAGTGTCCTCAGGATCCTAAGATCTACAAGCACTACTCCTTGCTGGCCTCCCTG CCTCTACTTCTGGGTCTTGGATTCCTGAGCCTTTGGTATCCAGTACAACTTGTGCAGAGTCTCCGTCACC CGACAGGAGCAGGCTCCCAGGGGCTGCAGACCAGCTACTCCGAGAAGTATCTGAGAACTCTTCTCTGCCC AAAGAAGTTGGATAGCTGCTCCCATCCTGCCTCCAAGCGTAGCCTCCTGTCTCGGGCCTGGGCCTTCTCC CATCATTCCATCTACACTCCACAGCCAGGATTCCGCCTGCCCTTGAAGCTGGTGATCTCGGCCACCCTGA CAGGAACAGCCACTTACCAGGTGGCCCTGCTGCTGCTGGTGAGCGTGGTGCCTACTGTGCAGAAGGTGAG GGCGGGGATCAACACAGATGTCTCCTACCTGCTGGCTGGCTTTGGGATCGTGCTCTCTGAAGACAGGCAG GAGGTGGTAGAGCTGGTGAAGCATCACCTATGGACTGTGGAAGCATGCTACATCTCAGCTCTGGTCTTGT CCTGCGCATCAACCTTCCTGCTCCTGATCCGATCCCTGAGGACACACAGGGCCAATCTTCAAGCACTACA CCGAGGGGCTGCCCTGGATCTGGACCCCCCTCTTCAGAGTATTCATCCCTCTCGCCAAGCCATAGTCAGC TGGATGAGCTTCTGTGCCTACCAGACGGCCTTCAGCTGCCTTGGGCTCCTGGTGCAGCAGGTCATCTTCT TCTTGGGGACCACATCCCTGGCCTTCCTGGTGTTTGTGCCTTTACTGCATGGCAGGAACCTCCTGCTGCT GCGATCCCTGGAATCCACGTGGCCCTTCTGGCTGACTGTGGCCTTAGCTGTAATCCTGCAGAACATAGCA GCCAACTGGATCTTCCTGAGGACTCACCATGGATACCCAGAGCTGACCAACCGGCGCATGCTCTGCGTAG CTACTTTTCTCCTCTTCCCCATCAACATGCTGGTGGGAGCCATAATGGCTGTCTGGCGGGTGCTCATCTC TTCTCTCTACAACACTGTTCACCTCGGCCAGATGGACCTCAGCCTGCTGCCGCAGAGGGCAGCCTCCCTG GATCCAGGCTACCACACATACCAAAACTTCCTGAGGATTGAGGCCAGCCAGTCACATCCAGGAGTCATAG CCTTCTGTGCCCTGCTCCTCCATGCTCCAAGTCCACAGCCCCGGCCCCCATTGGCCCCTCAGGACAGCCT CAGGCCGGCAGAAGAAGAAGAAGGGATGCAGTTGCTACAGACCAAGGACCTGATGGCCAAGGGAGCAGGA CACAAAGGCAGCCAGAGCAGGGCCCGCTGGGGTCTGGCCTACACATTGCTCCACAATCCAAGCCTACAGG CCTTCCGGAAGGCAGCCCTTACTAGTGCCAAGGCCAATGGCACCCAGCCC ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGATT ACAAGGATGACGACGATAAGGTTTAA >MR216996 representing NM_001162476
Red=Cloning site Green=Tags(s) MESQASENGSQTSSGVTDDYSSWYIEEPLGAEEVQPEGVIPLCQLTAPPALLHACLASLSFLVLLLLALL VRRRRLWPRCGHRGLGLPSPVDFLAGDLSWTVPAAVFVVLFSNLCLLLPDENPLPFLNLTAASSPDGEME TSRGPWKLLALLYYPALYYPLAACASAGHQAAFLLGTVLSWAHFGVQVWQKAECPQDPKIYKHYSLLASL PLLLGLGFLSLWYPVQLVQSLRHPTGAGSQGLQTSYSEKYLRTLLCPKKLDSCSHPASKRSLLSRAWAFS HHSIYTPQPGFRLPLKLVISATLTGTATYQVALLLLVSVVPTVQKVRAGINTDVSYLLAGFGIVLSEDRQ EVVELVKHHLWTVEACYISALVLSCASTFLLLIRSLRTHRANLQALHRGAALDLDPPLQSIHPSRQAIVS WMSFCAYQTAFSCLGLLVQQVIFFLGTTSLAFLVFVPLLHGRNLLLLRSLESTWPFWLTVALAVILQNIA ANWIFLRTHHGYPELTNRRMLCVATFLLFPINMLVGAIMAVWRVLISSLYNTVHLGQMDLSLLPQRAASL DPGYHTYQNFLRIEASQSHPGVIAFCALLLHAPSPQPRPPLAPQDSLRPAEEEEGMQLLQTKDLMAKGAG HKGSQSRARWGLAYTLLHNPSLQAFRKAALTSAKANGTQP TRTRPLEQKLISEEDLAANDILDYKDDDDKV |
| Restriction Sites |
SgfI-MluI
Cloning Scheme for this gene
Plasmid Map
|
| ACCN | NM_001162476 |
| ORF Size | 2010 bp |
| OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Reference Data | |
| RefSeq | NM_001162476.1, NP_001155948.1 |
| RefSeq Size | 3095 bp |
| RefSeq ORF | 2013 bp |
| Locus ID | 20897 |
| UniProt ID | O70491 |
| MW | 73.7 kDa |
| Gene Summary | Functions as retinol transporter (PubMed:23839944, PubMed:24852372). Accepts all-trans retinol from the extracellular retinol-binding protein RBP4, facilitates retinol transport across the cell membrane, and then transfers retinol to the cytoplasmic retinol-binding protein RBP1. Retinol uptake is enhanced by LRAT, an enzyme that converts retinol to all-trans retinyl esters, the storage forms of vitamin A (By similarity). Contributes to the activation of a signaling cascade that depends on retinol transport and LRAT-dependent generation of retinol metabolites that then trigger activation of JAK2 and its target STAT5, and ultimately increase the expression of SOCS3 and inhibit cellular responses to insulin (PubMed:21368206, PubMed:23839944). Important for the homeostasis of vitamin A and its derivatives, such as retinoic acid and 11-cis-retinal (PubMed:22467576, PubMed:24852372). STRA6-mediated transport is particularly important in the eye, and under conditions of dietary vitamin A deficiency (PubMed:22467576, PubMed:23839944, PubMed:24852372). Does not transport retinoic acid (By similarity).[UniProtKB/Swiss-Prot Function] |
Documents
| Product Manuals |
| FAQs |
| SDS |
Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| MG216996 | Stra6 (tGFP-tagged) - Mouse stimulated by retinoic acid gene 6 (Stra6) transcript variant 1, (10ug) |
CNY 6,370.00 |
|
| MR216996L3 | Lenti ORF clone of Stra6 (Myc-DDK-tagged) - Mouse stimulated by retinoic acid gene 6 (Stra6), transcript variant 1 |
CNY 7,700.00 |
|
| MR216996L4 | Lenti ORF clone of Stra6 (mGFP-tagged) - Mouse stimulated by retinoic acid gene 6 (Stra6), transcript variant 1 |
CNY 7,700.00 |
