Il23a (NM_031252) Mouse Tagged ORF Clone
CAT#: MR201920
- TrueORF®
Il23a (Myc-DDK-tagged) - Mouse interleukin 23, alpha subunit p19 (Il23a)
ORF Plasmid: tGFP
"NM_031252" in other vectors (4)
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CNY 2,400.00
CNY 3,705.00
Cited in 1 publication. |
CNY 300.00
Specifications
Product Data | |
Type | Mouse Tagged ORF Clone |
Tag | Myc-DDK |
Synonyms | IL-23; p19 |
Vector | pCMV6-Entry |
E. coli Selection | Kanamycin (25 ug/mL) |
Mammalian Cell Selection | Neomycin |
Sequence Data |
>MR201920 ORF sequence
Red=Cloning site Blue=ORF Green=Tags(s) TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC GCCGCGATCGCC ATGCTGGATTGCAGAGCAGTAATAATGCTATGGCTGTTGCCCTGGGTCACTCAGGGCCTGGCTGTGCCTA GGAGTAGCAGTCCTGACTGGGCTCAGTGCCAGCAGCTCTCTCGGAATCTCTGCATGCTAGCCTGGAACGC ACATGCACCAGCGGGACATATGAATCTACTAAGAGAAGAAGAGGATGAAGAGACTAAAAATAATGTGCCC CGTATCCAGTGTGAAGATGGTTGTGACCCACAAGGACTCAAGGACAACAGCCAGTTCTGCTTGCAAAGGA TCCGCCAAGGTCTGGCTTTTTATAAGCACCTGCTTGACTCTGACATCTTCAAAGGGGAGCCTGCTCTACT CCCTGATAGCCCCATGGAGCAACTTCACACCTCCCTACTAGGACTCAGCCAACTCCTCCAGCCAGAGGAT CACCCCCGGGAGACCCAACAGATGCCCAGCCTGAGTTCTAGTCAGCAGTGGCAGCGCCCCCTTCTCCGTT CCAAGATCCTTCGAAGCCTCCAGGCCTTTTTGGCCATAGCTGCCCGGGTCTTTGCCCACGGAGCAGCAAC TCTGACTGAGCCCTTAGTGCCAACAGCT ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGATT ACAAGGATGACGACGATAAGGTTTAA >MR201920 protein sequence
Red=Cloning site Green=Tags(s) MLDCRAVIMLWLLPWVTQGLAVPRSSSPDWAQCQQLSRNLCMLAWNAHAPAGHMNLLREEEDEETKNNVP RIQCEDGCDPQGLKDNSQFCLQRIRQGLAFYKHLLDSDIFKGEPALLPDSPMEQLHTSLLGLSQLLQPED HPRETQQMPSLSSSQQWQRPLLRSKILRSLQAFLAIAARVFAHGAATLTEPLVPTA TRTRPLEQKLISEEDLAANDILDYKDDDDKV |
Restriction Sites | SgfI-MluI Cloning Scheme for this gene Plasmid Map |
ACCN | NM_031252 |
ORF Size | 591 bp |
OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
Reference Data | |
RefSeq | NM_031252.2, NP_112542.1 |
RefSeq Size | 1359 bp |
RefSeq ORF | 591 bp |
Locus ID | 83430 |
UniProt ID | Q9EQ14 |
MW | 22.1 kDa |
Gene Summary | Associates with IL12B to form the IL-23 interleukin, a heterodimeric cytokine which functions in innate and adaptive immunity. IL-23 may constitute with IL-17 an acute response to infection in peripheral tissues. IL-23 binds to a heterodimeric receptor complex composed of IL12RB1 and IL23R, activates the Jak-Stat signaling cascade, stimulates memory rather than naive T-cells and promotes production of proinflammatory cytokines. IL-23 induces autoimmune inflammation and thus may be responsible for autoimmune inflammatory diseases and may be important for tumorigenesis.[UniProtKB/Swiss-Prot Function] |
Citations (1)
The use of this cDNA Clones has been cited in the following citations: |
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IL-17A treatment influences murine susceptibility to experimental Riemerella anatipestifer infection
,Cammayo, PLT;Fernandez-Colorado, CP;Flores, RA;Roy, A;Kim, S;Lillehoj, HS;Kim, WH;Min, W;,
Dev. Comp. Immunol.
,PubMed ID 31991165
[IL23A]
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Documents
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FAQs |
SDS |
Resources
Other Versions
SKU | Description | Size | Price |
---|---|---|---|
MC201218 | Il23a (untagged) - Mouse interleukin 23, alpha subunit p19 (Il23a), (10ug) |
CNY 2,000.00 |
|
MG201920 | Il23a (tGFP-tagged) - Mouse interleukin 23, alpha subunit p19 (Il23a) |
CNY 2,850.00 |
|
MR201920L3 | Lenti ORF clone of Il23a (Myc-DDK-tagged) - Mouse interleukin 23, alpha subunit p19 (Il23a) |
CNY 4,750.00 |
|
MR201920L4 | Lenti ORF clone of Il23a (mGFP-tagged) - Mouse interleukin 23, alpha subunit p19 (Il23a) |
CNY 4,750.00 |