CARD15 (NOD2) (NM_022162) Human 3' UTR Clone

Specifications

Product Data
Product Name	CARD15 (NOD2) (NM_022162) Human 3' UTR Clone
Vector	pMirTarget
Synonyms	ACUG; BLAU; BLAUS; CARD15; CD; CLR16.3; IBD1; NLRC2; NOD2B; PSORAS1; YAOS
ACCN	NM_022162
Insert Size	1286 bp
Sequence Data	Insert Sequence (showhide) >SC213503 3’UTR clone of NM_022162 The sequence shown below is from the reference sequence of NM_022162. The complete sequence of this clone may contain minor differences, such as SNPs. Blue=Stop Codon Red=Cloning site GGCAAGTTGGACGCCCGCAAGATCCGCGAGATTCTCATTAAGGCCAAGAAGGGCGGAAAGATCGCCGTG TAACAATTGGCAGAGCTCAGAATTCAAGCGATCGCC GGCTGCAGGGACACCAGACTCTTGCTTTGAAGTCTCCGGGAGGATGTTCGTCTCAGTTTGTTTGTGAGC AGGCTGTGAGTTTGGGCCCCAGAGGCTGGGTGACATGTGTTGGCAGCCTCTTCAAAATGAGCCCTGTCC TGCCTAAGGCTGAACTTGTTTTCTGGGAACACCATAGGTCACCTTTATTCTGGCAGAGGAGGGAGCATC AGTGCCCTCCAGGATAGACTTTTCCCAAGCCTACTTTTGCCATTGACTTCTTCCCAAGATTCAATCCCA GGATGTACAAGGACAGCCCCTCCTCCATAGTATGGGACTGGCCTCTGCTGATCCTCCCAGGCTTCCGTG TGGGTCAGTGGGGCCCATGGATGTGCTTGTTAACTGAGTGCCTTTTGGTGGAGAGGCCCGGCCTCTCAC AAAAGACCCCTTACCACTGCTCTGATGAAGAGGAGTACACAGAACACATAATTCAGGAAGCAGCTTTCC CCATGTCTCGACTCATCCATCCAGGCCATTCCCCGTCTCTGGTTCCTCCCCTCCTCCTGGACTCCTGCA CACGCTCCTTCCTCTGAGGCTGAAATTCAGAATATTAGTGACCTCAGCTTTGATATTTCACTTACAGCA CCCCCAACCCTGGCACCCAGGGTGGGAAGGGCTACACCTTAGCCTGCCCTCCTTTCCGGTGTTTAAGAC ATTTTTGGAAGGGGACACGTGACAGCCGTTTGTTCCCCAAGACATTCTAGGTTTGCAAGAAAAATATGA CCACACTCCAGCTGGGATCACATGTGGACTTTTATTTCCAGTGAAATCAGTTACTCTTCAGTTAAGCCT TTGGAAACAGCTCGACTTTAAAAAGCTCCAAATGCAGCTTTAAAAAATTAATCTGGGCCAGAATTTCAA ACGGCCTCACTAGGCTTCTGGTTGATGCCTGTGAACTGAACTCTGACAACAGACTTCTGAAATAGACCC ACAAGAGGCAGTTCCATTTCATTTGTGCCAGAATGCTTTAGGATGTACAGTTATGGATTGAAAGTTTAC AGGAAAAAAAATTAGGCCGTTCCTTCAAAGCAAATGTCTTCCTGGATTATTCAAAATGATGTATGTTGA AGCCTTTGTAAATTGTCAGATGCTGTGCAAATGTTATTATTTTAAACATTATGATGTGTGAAAACTGGT TAATATTTATAGGTCACTTTGTTTTACTGTCTTAAGTTTATACTCTTATAGACAACATGGCCGTGAACT TTATGCTGTAAATAATCAGAGGGGAATAAACTGTTGAGTCAAAA ACGCGTAAGCGGCCGCGGCATCTAGATTCGAAGAAAATGACCGACCAAGCGACGCCCAACCTGCCATCA CGAGATTTCGATTCCACCGCCGCCTTCTATGAAAGG
Restriction Sites	SgfI-MluI
OTI Disclaimer	Our molecular clone sequence data has been matched to the sequence identifier above as a point of reference. Note that the complete sequence of this clone is largely the same as the reference sequence but may contain minor differences , e.g., single nucleotide polymorphisms (SNPs).
Reference Data
RefSeq	NM_022162.3
Synonyms	ACUG; BLAU; BLAUS; CARD15; CD; CLR16.3; IBD1; NLRC2; NOD2B; PSORAS1; YAOS
Summary	This gene is a member of the Nod1/Apaf-1 family and encodes a protein with two caspase recruitment (CARD) domains and six leucine-rich repeats (LRRs). The protein is primarily expressed in the peripheral blood leukocytes. It plays a role in the immune response to intracellular bacterial lipopolysaccharides (LPS) by recognizing the muramyl dipeptide (MDP) derived from them and activating the NFKB protein. Mutations in this gene have been associated with Crohn disease and Blau syndrome. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, Jun 2014]
Locus ID	64127
MW	47.2

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