CYP27B1 (NM_000785) Human 3' UTR Clone

Specifications

Product Data
Product Name	CYP27B1 (NM_000785) Human 3' UTR Clone
Vector	pMirTarget
Synonyms	CP2B; CYP1; CYP1alpha; CYP27B; P450c1; PDDR; VDD1; VDDR; VDDRI; VDR
ACCN	NM_000785
Insert Size	838 bp
Sequence Data	Insert Sequence (showhide) >SC210195 3’UTR clone of NM_000785 The sequence shown below is from the reference sequence of NM_000785. The complete sequence of this clone may contain minor differences, such as SNPs. Blue=Stop Codon Red=Cloning site GGCAAGTTGGACGCCCGCAAGATCCGCGAGATTCTCATTAAGGCCAAGAAGGGCGGAAAGATCGCCGTG TAACAATTGGCAGAGCTCAGAATTCAAGCGATCGCC AGCATCAACCTACAGTTTTTGGACAGATAGTCCCATGGAAAGAGACTGTCATCATCACCCTTTCATTCA TCATAGGGATAAGATTTTTTGTAGGCACAAGACCAAGGTATACATCTTCCCCTAATGCCTATCTGACCA AACTGGATAGAACCACCATAGTGAAGTGTGAGGCGGCCCTGACCAATGTGTGAAGTATGCACTTGGCCT GACTCAGGAAGCCAGGTGAGAAAACCATGGTCTCTCTGCTTGCTTGGCCCTTCTGATCATGTATGCATC CCCCAAGGATGAAATCAGATTTTAACTAATAATGCTGGATGGCCTGAGGAAAGATTCAACTGCCTCTCT TTTTGGGCTTTCATAGTGTTCATTGATGCTGCTGGCTAAGCATTTATCAAAGCATAAGCTCAGTAACTG TGCATCTGGTCTGTACCTGGTTGGTCCTTCGTCTTTGCATGTAAGCTCTTTGAGAGGAAGGGTGAAGCC TTATTTGTTTTTTATGTCCCCTGCCAGGGCCTGTCTCTGACTAGGTGTCACCATACACATTCTTAGATT GAATCTGAACCATGTGGCAGAAGGGATAAGCAGCTTACTTAGTAGGCTCTGTCTACCCCCTTCCTTCTT TGTCTTGCCCCTAGGAAGGTGAATCTGCCCTAGCCTGGTTTACGGTTTCTTATAACTCTCCTTTGCTCT CTGGCCACTATTAAGTGGGTTTGCCCCATCACTTAGTTCTCAGGCAGAGACATCTTTGGGCCTGTCCCT GCCCAGGCCTCTGGCTTTTTATATTGAAAATTTTTAAATATTCACAAATTTTAGAATAAATCAAATATT CCATTCTTGA ACGCGTAAGCGGCCGCGGCATCTAGATTCGAAGAAAATGACCGACCAAGCGACGCCCAACCTGCCATCA CGAGATTTCGATTCCACCGCCGCCTTCTATGAAAGG
Restriction Sites	SgfI-MluI
OTI Disclaimer	Our molecular clone sequence data has been matched to the sequence identifier above as a point of reference. Note that the complete sequence of this clone is largely the same as the reference sequence but may contain minor differences , e.g., single nucleotide polymorphisms (SNPs).
Reference Data
RefSeq	NM_000785.4
Synonyms	CP2B; CYP1; CYP1alpha; CYP27B; P450c1; PDDR; VDD1; VDDR; VDDRI; VDR
Summary	This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. The protein encoded by this gene localizes to the inner mitochondrial membrane where it hydroxylates 25-hydroxyvitamin D3 at the 1alpha position. This reaction synthesizes 1alpha,25-dihydroxyvitamin D3, the active form of vitamin D3, which binds to the vitamin D receptor and regulates calcium metabolism. Thus this enzyme regulates the level of biologically active vitamin D and plays an important role in calcium homeostasis. Mutations in this gene can result in vitamin D-dependent rickets type I. [provided by RefSeq, Jul 2008]
Locus ID	1594
MW	31.4

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