KCNA5 (NM_002234) Human 3' UTR Clone

Specifications

Product Data
Product Name	KCNA5 (NM_002234) Human 3' UTR Clone
Vector	pMirTarget
Synonyms	ATFB7; HCK1; HK2; HPCN1; KV1.5; PCN1
ACCN	NM_002234
Insert Size	829 bp
Sequence Data	Insert Sequence (showhide) >SC209953 3’UTR clone of NM_002234 The sequence shown below is from the reference sequence of NM_002234. The complete sequence of this clone may contain minor differences, such as SNPs. Blue=Stop Codon Red=Cloning site GGCAAGTTGGACGCCCGCAAGATCCGCGAGATTCTCATTAAGGCCAAGAAGGGCGGAAAGATCGCCGTG TAACAATTGGCAGAGCTCAGAATTCAAGCGATCGCC CTGGACACCAGCCGGGAAACAGATTTGTGAAAGGAGATTCAGGCAGACTGGTGGCAGTGGAGTAGGGAA TGGGAGGCTTGCTGAACATGGATATCTACATTATACCGCAGAGTATTTGAAGTCACACTGTAACCTCAG TCTACCCCTCTCCTTTCACTCCTTTCCTCCCTCCCTCGATCCCCCCATTTTCTCTATTCTTTCCATGAC ACCCAAGGGTCGCCTATTTTTAAAAAGTACCACATTCCATGACGCAGGAGCTGTGGAAATGGTGAGCGC TGTGAGATGGATGTATTTGTAGCCAGTCTCCTATACCCAGCAGAGGGATAACCCAAACAAAAATGACTC TAAATAGCCCAGATCCCAAGAGATTATGTAACTCCTCCATCCATGTGTTCCAAATTTGCTTTACATATG ATTGTATTTGTGTATAGGGGAAAATATTATTTTTATGCCTGGTAAGTGGCTTTTTGTACTGTAGTTCAG ATAGAGATATTTTGGGTATATTTTCAAGATACATGTTGTATTTATGGAAGAAAGAGTTGTCCTGATGTT TTTCTGTGTTACTTATATTAGAGTCAGAGATCTTGGTATGGGCTGTTCTGTTTCCTGTGTCTCCAAGCC TCTGTCTTTTCTGGGATGTGGTATTGGTGCTTTGTGTCTAGGGCAGAGTATGTTCTTGAAGAAAGGCAA ATCTGACTTTTTCTGTGCGCCTTAAACAATTCTTGTAACTTTCTTCAAAAAGCATTTTAATGATATTGG AGGAATACTTCTGATAATTTATTGTCTTTATTTTTATCCCAGGAAATAAAAGGTTACCTTGTTGAGGCAA ACGCGTAAGCGGCCGCGGCATCTAGATTCGAAGAAAATGACCGACCAAGCGACGCCCAACCTGCCATCA CGAGATTTCGATTCCACCGCCGCCTTCTATGAAAGG
Restriction Sites	SgfI-MluI
OTI Disclaimer	Our molecular clone sequence data has been matched to the sequence identifier above as a point of reference. Note that the complete sequence of this clone is largely the same as the reference sequence but may contain minor differences , e.g., single nucleotide polymorphisms (SNPs).
Reference Data
RefSeq	NM_002234.4
Synonyms	ATFB7; HCK1; HK2; HPCN1; KV1.5; PCN1
Summary	Potassium channels represent the most complex class of voltage-gated ino channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. Four sequence-related potassium channel genes - shaker, shaw, shab, and shal - have been identified in Drosophila, and each has been shown to have human homolog(s). This gene encodes a member of the potassium channel, voltage-gated, shaker-related subfamily. This member contains six membrane-spanning domains with a shaker-type repeat in the fourth segment. It belongs to the delayed rectifier class, the function of which could restore the resting membrane potential of beta cells after depolarization and thereby contribute to the regulation of insulin secretion. This gene is intronless, and the gene is clustered with genes KCNA1 and KCNA6 on chromosome 12. Defects in this gene are a cause of familial atrial fibrillation type 7 (ATFB7). [provided by RefSeq, May 2012]
Locus ID	3741
MW	32.7

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