ATF6 (NM_007348) Human 3' UTR Clone

CAT#: SC205479

3' UTR clone of activating transcription factor 6 (ATF6) for miRNA target validation



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CNY 4,845.00


货期*
3周

规格
    • 10 ug

Cited in 2 publications.

Product images

经常一起买 (2)
Firefly luciferase assay kit, 150 assays
    • 1 kit

CNY 1,520.00


DH5α Chemically Competent Cells (≥10^8 cfu/μg of pUC19 DNA)
    • 5 x 200 ul

CNY 1,280.00

Specifications

Product Data
Product Name ATF6 (NM_007348) Human 3' UTR Clone
Vector pMirTarget
Synonyms ACHM7; ATF6A
ACCN NM_007348
Insert Size 2000 bp
Sequence Data
>SC205479 3’UTR clone of NM_007348
The sequence shown below is from the reference sequence of NM_007348. The complete sequence of this clone may contain minor differences, such as SNPs.
Blue=Stop Codon Red=Cloning site

GGCAAGTTGGACGCCCGCAAGATCCGCGAGATTCTCATTAAGGCCAAGAAGGGCGGAAAGATCGCCGTG
TAACAATTGGCAGAGCTCAGAATTCAAGCGATCGCC
GTCAGCACCATCCCTGAGTCATTACAATAGCACCCTGCAGCTATGCTGGAAAACTGAGCGTGGGACCCT
GCCAGACTGAAGAGCAGGTGAGCAAAATGCTGCTTTCTGCCTTGGTGGCAGGCAGAGAACTGTCTCGTA
CTAGAATTCAAGGAGGAAAGAAGAAGAAATAAAAGAAGCTGCTCCATTTTTCATCATCTACCCATCTAT
TTGGAAAGCACTGGAATTCAGATGCAAGAGAACAATGTTTCTTCAGTGGCAAATGTAGCCCTGCATCCT
CCAGTGTTACCTGGTGTAGATTTTTTTTTCTGTACCTTTCTAAACCTCTCTTCCCTCTGTGATGGTTTT
GTGTTTAAACAGTCATCTTCTTTTAAATAATATCCACCTCTCCTTTTTGCCATTTCACTTATTGATTCA
TAAAGTGAATTTTATTTAAAGCTATGCCACACATGCATGTTCAAATGGTTTCCACTGATTCGATTTTTC
ATTCATTTAATGCAAACCCATTCTGGATATTGTGCTTATTTGAGAAAACACATTTCAAAACCAGAAAAG
CCAAAAACACTCCAAAAACAAGCAAAACAATTTGGAGCTTTAGATAAAAGGAAAAACTCCCAGTTGGTA
AAGTTTATCTTTACTTAGGATTTGTGGCTCACACCTAAACAAAGGGGGTCAGGGAGTGGGTACAAATTT
GAGAAAATAGAAGGGTAAGGGAAGGGCCAGTGGTGGGGTTTGGAGAGAGGAGATAGCTCCATTAATACA
CATGTTTAAAAGATGGAAAGTTCACGCCTGTAATCCCAGCACTTTGGGAGGCCGAGGCGGGTGGATCAC
GAGGTCAGGAGATCAAGACCATCCCGGCTAAAACGGTGAAACCCCGTCTCTACTAAAAATACAAAAAAT
TAGCCGGGCGTAGTGACGGGCGCCTGTAGTCCCAGCTACTTGGGAGGCTGAGGCAGGAGAATGGCGTGA
ACCCGGGAGGCGGAGCTTGCAGTGAGCCGAGATCCCGCCACTGCACTCCAGCCTGGGCGACAGAGCGAG
ACTCCGTCTCAAAAAAAAAAAAAAAAAAAAAAAAAGATGGAAAGTTCGATGTGACTGCAGTATGAGATT
AAAGCCACAACTATTGTTTATTTTGGGGACTCTAGGCCACCAAGTATTAGCACACATACTTATGTTTTC
TCTACTAATCTGGTCCAGGTCCTCATGGACCACAGGACAAAGCTTTCATTTTCATTCATTCTTCTATTG
AAATTATACCAAATTCAGCTGAGGAATATGGAAGTAACTTTAGACTTAAACAAGACAAAAGTTTTTTCA
CTGAAGAATTGACAAGTATTTGCTCCTTAAAACAACGCAGATTAGTGAACGTGGATTCCTGCTGAGGGA
GTGCATCCCATAATATGGCAATAATTTTCAGTTTCTCCAACGAAAAGATAGTGAAGGAATTAAATCTTT
TGTCCTCCCATGGTTAAAAAAAAAAAAAAAGCTGTGTTCATTTTTACTGTACTATGCCTCTTTTTTCAC
CATAGTAGACAATTATGTTTCATTTGATGAATTCATAGAACTGGATCTCATACAGCGATGTCCTCTCTA
ATGTTCTACCTTTCAGTTTCTAAAGTGAGTCTTCCTCCCTCTCCTACAAAACTTTTCAATTTTTTGATG
TAACTCATCTACAAATACTGTTTCTTACCCCAGTTGACTTGCCTTTGTCAGATTTCTTCTTGTTCCACA
CTATAGCAATCAATTTCTCTTCTTCCTTACAAGAAAGGGAACGAGAAATTGTAGCAACCTCTCAAGGAT
TATATGCAGCTAGTTAGTTTTCTGCCTGTGAAATTAGGTCTGGCTCCTAAATAATTTTAAAGAACCATC
AGCACTTCTAACTCTCTGGACAGGTGCCTCTTTGTCCAAGCTAGTTAAATGCTTTCCAAGGAAATCAGT
TCAACTTTTGTGAGCGGGGAAAAGCAGGGCTTTATTGTTGTGTTACCTGGGAGTCTGGAGTTTGAAAA
ACGCGTAAGCGGCCGCGGCATCTAGATTCGAAGAAAATGACCGACCAAGCGACGCCCAACCTGCCATCA
CGAGATTTCGATTCCACCGCCGCCTTCTATGAAAGG
Restriction Sites SgfI-MluI     
OTI Disclaimer Our molecular clone sequence data has been matched to the sequence identifier above as a point of reference. Note that the complete sequence of this clone is largely the same as the reference sequence but may contain minor differences , e.g., single nucleotide polymorphisms (SNPs).
Reference Data
RefSeq NM_007348.4
Synonyms ACHM7; ATF6A
Summary This gene encodes a transcription factor that activates target genes for the unfolded protein response (UPR) during endoplasmic reticulum (ER) stress. Although it is a transcription factor, this protein is unusual in that it is synthesized as a transmembrane protein that is embedded in the ER. It functions as an ER stress sensor/transducer, and following ER stress-induced proteolysis, it functions as a nuclear transcription factor via a cis-acting ER stress response element (ERSE) that is present in the promoters of genes encoding ER chaperones. This protein has been identified as a survival factor for quiescent but not proliferative squamous carcinoma cells. There have been conflicting reports about the association of polymorphisms in this gene with diabetes in different populations, but another polymorphism has been associated with increased plasma cholesterol levels. This gene is also thought to be a potential therapeutic target for cystic fibrosis. [provided by RefSeq, Aug 2011]
Locus ID 22926
MW 76.3
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Citations (2)

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