CD63 Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	WB
Recommend Dilution	WB: 1:500~1:1000
Reactivity	Human
Host	Rabbit
Clonality	Polyclonal
Immunogen	Recombinant protein of human CD63
Formulation	PBS with 0.02% sodium azide, 50% glycerol, pH7.3
Concentration	0.91mg/ml
Purification	Purified from the immunized serum by affinity chromatography (Protein A/G)
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Predicted Protein Size	25.5 kDa
Gene Name	CD63 molecule
Database Link	NP_001771 Entrez Gene 967 Human UniProt ID P08962
Background	The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. The encoded protein is a cell surface glycoprotein that is known to complex with integrins. It may function as a blood platelet activation marker. Deficiency of this protein is associated with Hermansky-Pudlak syndrome. Also this gene has been associated with tumor progression. Alternative splicing results in multiple transcript variants encoding different protein isoforms. [provided by RefSeq, Apr 2012]
Synonyms	LAMP-3; ME491; MLA1; OMA81H; TSPAN30
Reference Data
Protein Families	Druggable Genome, Transmembrane
Protein Pathways	Lysosome

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