MOBK1B (MOB1A) Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	IHC, WB
Recommend Dilution	WB: 500-2000 WB positive control: Hela and Jurkat cells, mouse liver tissue, K562 and A375 cells IHC: 50-200 Positive control: Human liver cancer Predicted cell location: Cytoplasm and Nucleus
Reactivity	Human, Mouse, Rat
Host	Rabbit
Clonality	Polyclonal
Immunogen	Synthetic peptide of human MOB1A
Formulation	pH7.4 PBS, 0.05% NaN3, 40% Glyceroln
Concentration	lot specific
Purification	Antigen affinity purification
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Predicted Protein Size	25 kDa
Gene Name	MOB kinase activator 1A
Database Link	NP_060691 Entrez Gene 232157 MouseEntrez Gene 297387 RatEntrez Gene 55233 Human UniProt ID Q9H8S9
Background	MOB1 was first identified in yeast as a protein that binds to Mps with essential roles in the completion of mitosis and the maintenance of ploidy. Its Drosophila and mammalian homologs, Mats and MOB1, respectively, are involved in the Hippo signaling tumor suppressor pathway, which plays a critical role in organ size regulation and which has been implicated in cancer development . There are two MOB1 proteins in humans, MOB1α and MOB1β, that are encoded by two different genes but which have greater than 95% amino acid sequence identity.
Synonyms	C2orf6; MATS1; MOB1; Mob4B; MOBK1B; MOBKL1B
Reference Data
Protein Families	Druggable Genome

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