Myosin heavy chain 3 (MYH3) Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	IHC, WB
Recommend Dilution	WB: 1 - 2 ug/mL, IHC: 5 ug/mL
Reactivity	Human, Mouse, Rat
Host	Rabbit
Clonality	Polyclonal
Immunogen	MYH3 antibody was raised against a 19 amino acid peptide near the amino terminus of human MYH3.
Formulation	PBS containing 0.02% sodium azide.
Concentration	1 mg/ml
Purification	MYH3 antibody is affinity chromatography purified via peptide column.
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Predicted Protein Size	Predicted: 213 kDa; Observed: 240 kDa
Gene Name	myosin, heavy chain 3, skeletal muscle, embryonic
Database Link	NP_002461 Entrez Gene 4621 Human UniProt ID P11055
Background	Myosins are actin-based motor proteins that function in the generation of mechanical force in eukaryotic cells (1). MYH3 (myosin, heavy chain, skeletal muscle, embryonic) plays a significant role in skeletal muscle development (2) and is also essential for the proper morphology and function of the developing heart (3). Mutations in this gene have been associated with Freeman-Sheldon syndrome and Sheldon-Hall syndrome (4).
Synonyms	Myosin heavy chain 3, Myosin-3, Myosin heavy chain skeletal muscle embryonic, HEMHC, MYHC-EMB, MYHSE1, SMHCE
Reference Data

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