SMAD5 Mouse Monoclonal Antibody [Clone ID: 4B10-B10-B6]

CAT#: TA347048

Mouse Monoclonal SMAD5 (C-terminus) Antibody

Size: 20 ul 100 ul



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CNY 2,700.00


货期*
2周

规格
    • 100 ul

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    • 100 ug

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Specifications

Product Data
Clone Name 4B10-B10-B6
Applications FC, IF, WB
Recommend Dilution WB: 1:1000, IF: 1:75, FC: 1:100
Reactivity Human
Host Mouse
Clonality Monoclonal
Immunogen The immunogen for SMAD5 antibody: purified recombinant human SMAD5 (C-terminus) protein fragments expressed in E.coli.
Formulation Purified mouse monoclonal in buffer containing 0.1M Tris-Glycine (pH 7.4, 150 mM NaCl) with 0.02% sodium azide, 50%,glycerol
Purification Affinity purified
Conjugation Unconjugated
Storage Condition Store at -20°C as received.
Predicted Protein Size 60 kDa
Gene Name SMAD family member 5
Background SMAD5 is a member of the Mothers Against Dpp (MAD)-related family of proteins. It is a receptor-regulated SMAD (R-SMAD), and acts as an intracellular signal transducer for the transforming growth factor beta superfamily. SMAD5 is activated through serine phosphorylation by BMP (bone morphogenetic proteins) type 1 receptor kinase. It is cytoplasmic in the absence of its ligand and migrates into the nucleus upon phosphorylation and complex formation with SMAD4. Here the SMAD5/SMAD4 complex stimulates the transcription of target genes.
Synonyms DWFC; JV5-1; MADH5
Reference Data
Protein Families Cancer stem cells, Druggable Genome, ES Cell Differentiation/IPS, Stem cell relevant signaling - JAK/STAT signaling pathway, Stem cell relevant signaling - TGFb/BMP signaling pathway, Transcription Factors
Protein Pathways TGF-beta signaling pathway
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.
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