Slc32a1 Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	IF, IHC, WB
Recommend Dilution	WB: 1:200-1:2000; IHC: 1:100-1:3000
Reactivity	Human, Mouse, Rat
Host	Rabbit
Clonality	Polyclonal
Immunogen	Peptide (C)GEFGGHDKPKITAWE, corresponding to amino acid residues 106-120 of rat vesicular GABA transporter. Cytoplasmic, N-terminus
Formulation	Lyophilized. Concentration before lyophilization ~0.8mg/ml (lot dependent, please refer to CoA along with shipment for actual concentration). Buffer before lyophilization: Phosphate buffered saline (PBS), pH 7.4, 1% BSA, 0.05% NaN3.
Reconstitution Method	Add 50 ul double distilled water (DDW) to the lyophilized powder.
Purification	Affinity purified on immobilized antigen.
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Gene Name	solute carrier family 32 member 1
Database Link	NP_113970 Entrez Gene 22348 MouseEntrez Gene 140679 HumanEntrez Gene 83612 Rat UniProt ID O35458
Background	The superfamily of amino acid transporters includes SLC32, SLC36 and SLC38 families. SLC32 has only one family member, the vesicular inhibitory amino acid transporter (VIAAT) or vesicular GABA transporter (VGAT). VGAT is responsible for the uptake of GABA and Glycine in exchange of protons, and their release from nerve terminals. The transporter is organized into ten membrane spanning domains, a cytosolic N-terminus and a luminal C-terminal tail. In many regions in the brain, where it is expressed, it is found constitutively phosphorylated, although the biological significance is currently unknown. VGAT is expressed on synaptic vesicles of GABAergic and glycynergic neurons. The transporter is also detected in the pituitary gland and in the pancreas.
Synonyms	bA122O1.1; hVIAAT; VGAT; VIAAT
Reference Data

*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.