TrkB (NTRK2) Goat Polyclonal Antibody

Specifications

Product Data
Applications	WB
Recommend Dilution	ELISA: 1:64000; WB: 0.05-0.2µg/ml
Reactivity	Human, Mouse, Rat, Dog
Host	Goat
Clonality	Polyclonal
Immunogen	Peptide with sequence C-KTLQEAKSSPDTQ, from the internal region of the protein sequence according to NP_006171.2; NP_001007098.1; NP_001018074.1; NP_001018075.1; NP_001018076.1.
Formulation	Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. Aliquot and store at -20°C. Minimize freezing and thawing.
Concentration	lot specific
Purification	Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Gene Name	neurotrophic receptor tyrosine kinase 2
Database Link	NP_006171 Entrez Gene 18212 MouseEntrez Gene 25054 RatEntrez Gene 484147 DogEntrez Gene 4915 Human UniProt ID Q16620
Synonyms	GP145-TrkB; trk-B; TRKB
Note	Approx 100kDa band observed in Human Brain (Hippocampus, Cerebral Cortex and Cerebellum) lysates (calculated MW of 93.8kDa according to NP_006171.2). Recommended concentration: 0.05-0.2µg/ml. This antibody is expected to recognise isoforms a (NP_006171.2), b ((NP_001007098.1), c (NP_001018074.1), d (NP_001018075.1), e ( NP_001018076.1).
Reference Data
Protein Families	Druggable Genome, Protein Kinase, Transmembrane
Protein Pathways	MAPK signaling pathway, Neurotrophin signaling pathway

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