gamma Adaptin (AP1G1) Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	IHC
Recommend Dilution	IHC: 25-100 Positive control: Human breast cancer Predicted cell location: Cytoplasm
Reactivity	Human, Mouse
Host	Rabbit
Clonality	Polyclonal
Immunogen	Synthetic peptide corresponding to a region derived from 801-813 amino acids of Human adaptor-related protein complex 1, gamma 1 subunit
Formulation	PBS pH7.3, 0.05% NaN3, 50% glycerol
Concentration	lot specific
Purification	Antigen affinity purification
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Gene Name	adaptor related protein complex 1 gamma 1 subunit
Database Link	NP_001119 Entrez Gene 11765 MouseEntrez Gene 164 Human UniProt ID O43747
Background	Adaptins are important components of clathrin-coated vesicles transporting ligand-receptor complexes from the plasma membrane or from the trans-Golgi network to lysosomes. The adaptin family of proteins is composed of four classes of molecules named alpha; beta-; beta prime- and gamma- adaptins. Adaptins; together with medium and small subunits; form a heterotetrameric complex called an adaptor; whose role is to promote the formation of clathrin-coated pits and vesicles. The protein encoded by this gene is a gamma-adaptin protein and it belongs to the adaptor complexes large subunits family. Two transcript variants encoding different isoforms have been found for this gene.
Synonyms	ADTG; CLAPG1
Reference Data
Protein Pathways	Lysosome

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