XPNPEP3 Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	IHC, WB
Recommend Dilution	WB: 200-1000 WB positive control: MCF7 and A431 cells IHC: 25-100 Positive control: Human lymphoma Predicted cell location: Cytoplasm
Reactivity	Human
Host	Rabbit
Clonality	Polyclonal
Immunogen	Synthetic peptide corresponding to a region derived from 34-49 amino acids of human X-prolyl aminopeptidase (aminopeptidase P) 3, putative
Formulation	PBS pH7.3, 0.05% NaN3, 50% glycerol
Concentration	lot specific
Purification	Antigen affinity purification
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Predicted Protein Size	57 kDa
Gene Name	X-prolyl aminopeptidase 3, mitochondrial
Database Link	NP_071381 Entrez Gene 63929 Human UniProt ID Q9NQH7
Background	The protein encoded by this gene belongs to the family of X-pro-aminopeptidases that utilize a metal cofactor; and remove the N-terminal amino acid from peptides with a proline residue in the penultimate position. This protein has been shown to localize to the mitochondria of renal cells; and have a role in ciliary function. Mutations in this gene are associated with nephronophthisis-like nephropathy-1. Alternatively spliced transcript variants encoding different isoforms have been noted for this gene; however; expression of some of these isoforms in vivo is not known.
Synonyms	APP3; ICP55; NPHPL1
Reference Data
Protein Families	Druggable Genome, Protease

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