TRIP6 Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	IF, WB
Recommend Dilution	WB: 1 ug/mL, ICC:ug/mL, IF: 20 ug/mL
Reactivity	Human, Mouse
Host	Rabbit
Clonality	Polyclonal
Immunogen	TRIP6 antibody was raised against a 15 amino acid synthetic peptide near the center of human TRIP6.
Formulation	TRIP6 Antibody is supplied in PBS containing 0.02% sodium azide.
Concentration	1ug/ul
Purification	TRIP6 Antibody is affinity chromatography purified via peptide column.
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Gene Name	thyroid hormone receptor interactor 6
Database Link	NP_003293 Entrez Gene 22051 MouseEntrez Gene 7205 Human UniProt ID Q15654
Background	TRIP6 Antibody: TRIP6 (Thyroid receptor interacting protein 6) is a zyxin-related focal adhesion molecule involved in cell motility and antiapoptotic responses. TRIP6 is predominantly expressed in kidney, liver and lung. It has three LIM domains, a PDZ-binding motif, a Crk SH2-binding motif and/or other protein interacting domains. TRIP6 regulates NF-κB activation and interacts with RICK and TRAF2, proteins that are involved in TNF signaling. TRIP6 antagonizes Fas-induced apoptosis and promotes Fas-mediated cell migration in apoptosis-resistant glioma cells via Src-dependent phosphorylation of TRIP6 at Tyr-55.
Synonyms	OIP-1; OIP1; TRIP-6; TRIP6i2; ZRP-1
Reference Data
Protein Families	Druggable Genome
Protein Pathways	NOD-like receptor signaling pathway

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