GADD45G Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	IF, WB
Recommend Dilution	ICC/IF:1:100-1:1000; WB:1:500-1:3000
Reactivity	Human, Rat, Pig, Bovine, Rhesus Monkey, X. tropicalis, Mouse
Host	Rabbit
Clonality	Polyclonal
Immunogen	Synthetic peptide corresponding to a region within amino acids 96 and 159 of GADD45G (Uniprot ID#O95257)
Formulation	0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.
Concentration	lot specific
Purification	Purified by antigen-affinity chromatography.
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Predicted Protein Size	17 kDa
Gene Name	growth arrest and DNA damage inducible gamma
Database Link	NP_006696 Entrez Gene 23882 MouseEntrez Gene 291005 RatEntrez Gene 10912 Human UniProt ID O95257
Background	This gene is a member of a group of genes whose transcript levels are increased following stressful growth arrest conditions and treatment with DNA-damaging agents. The protein encoded by this gene responds to environmental stresses by mediating activation of the p38/JNK pathway via MTK1/MEKK4 kinase. The GADD45G is highly expressed in placenta. [provided by RefSeq]
Synonyms	CR6; DDIT2; GADD45gamma; GRP17
Note	Seq homology of immunogen across species: Mouse (93%), Rat (93%), Xenopus Tropicalis (86%), Pig (93%), Rhesus Monkey (100%), Bovine (93%)
Reference Data
Protein Pathways	Cell cycle, MAPK signaling pathway, p53 signaling pathway

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