CYP46 (CYP46A1) Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	ICC/IF, IHC, WB
Recommend Dilution	Western Blot: 1:1000, Immunohistochemistry-Paraffin: 1:200, Immunohistochemistry: 1:200, Immunocytochemistry/ Immunofluorescence: 1:500
Reactivity	Human
Host	Rabbit
Clonality	Polyclonal
Immunogen	A synthetic peptide corresponding to residues between 200-250 of human Cyp46.
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Gene Name	cytochrome P450 family 46 subfamily A member 1
Database Link	NP_006659 Entrez Gene 10858 Human UniProt ID Q9Y6A2
Background	The Cyp46 gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This endoplasmic reticulum proein is expressed in the brain, where it converts cholesterol to 24S-hydroxycholesterol.
Synonyms	CP46; CYP46
Reference Data
Protein Families	Druggable Genome, P450
Protein Pathways	Primary bile acid biosynthesis

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