IRF5 (176-240) Mouse Monoclonal Antibody [Clone ID: 10T1]

Specifications

Product Data
Clone Name	10T1
Applications	ELISA, FC, IF, IHC, IP, WB
Recommend Dilution	ELISA. Western blot: 1/500-1/1,000. Immunoprecipitation. Immunohistochemistry on paraffin sections: 1/50. Immunocytochemistry / Immunoflourescence. Flow cytometry.
Reactivity	Human, Mouse
Host	Mouse
Clonality	Monoclonal
Immunogen	Recombinant Human IRF-5 (176-240 aa) purified from E. coli
Specificity	The antibody recognizes Interferon Regulatory Factor 5 (IRF-5) at aa 176-240.
Formulation	PBS, pH 7.4 containing 0.02% Sodium Azide and 10% Glycerol State: Purified State: Liquid purified IgG fraction
Concentration	lot specific
Purification	Affinity Chromatography on Protein G
Conjugation	Unconjugated
Storage Condition	Store undiluted at 2-8°C for up to two weeks or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing.
Gene Name	interferon regulatory factor 5
Database Link	Entrez Gene 3663 Human UniProt ID Q13568
Background	IRF-5 is a member of IRF family, which plays a critical role in the regulation of genes induced by viral infection, immunostimulation and cell growth regulation. The expression of IRF-5 is limited to lymphoid organs, dendritic cells, and peripheral blood lymphocytes, but is not expressed in numerous leukemia and lymphoma cell lines. Three IRFs(IRF-3, IRF-5, IRF-7) function as direct transducers of virus-mediated signaling and play a critical role in the expression of type I interferon genes and some chemokines.
Synonyms	Interferon regulatory factor 5, IRF-5
Reference Data

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