Troponin I fast skeletal muscle (TNNI2) Mouse Monoclonal Antibody [Clone ID: OTI1H1]

CAT#: CF807822

Carrier-free (BSA/glycerol-free) TNNI2 mouse monoclonal antibody, clone OTI1H1 (formerly 1H1)

Formulation: Standard Carrier-Free



  View other "OTI1H1" antibodies (4)

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CNY 3,999.00


货期*
2周

规格
    • 100 ug

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经常一起买 (2)
Biotinylation Labelling Kit formatted 4 x 0.05mg
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HRP Conjugation kit for 0.2mg IgG
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Specifications

Product Data
Clone Name OTI1H1
Applications WB
Recommend Dilution WB 1:2000
Reactivity Human, Mouse, Rat
Host Mouse
Clonality Monoclonal
Immunogen Full length human recombinant protein of human TNNI2 (NP_003273) produced in E.coli.
Formulation Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)
Reconstitution Method For reconstitution, we recommend adding 100uL distilled water to a final antibody concentration of about 1 mg/mL. To use this carrier-free antibody for conjugation experiment, we strongly recommend performing another round of desalting process. (OriGene recommends Zeba Spin Desalting Columns, 7KMWCO from Thermo Scientific)
Purification Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
Conjugation Unconjugated
Storage Condition Store at -20°C as received.
Predicted Protein Size 21.2 kDa
Gene Name troponin I2, fast skeletal type
Background This gene encodes a fast-twitch skeletal muscle protein, a member of the troponin I gene family, and a component of the troponin complex including troponin T, troponin C and troponin I subunits. The troponin complex, along with tropomyosin, is responsible for the calcium-dependent regulation of striated muscle contraction. Mouse studies show that this component is also present in vascular smooth muscle and may play a role in regulation of smooth muscle function. In addition to muscle tissues, this protein is found in corneal epithelium, cartilage where it is an inhibitor of angiogenesis to inhibit tumor growth and metastasis, and mammary gland where it functions as a co-activator of estrogen receptor-related receptor alpha. This protein also suppresses tumor growth in human ovarian carcinoma. Mutations in this gene cause myopathy and distal arthrogryposis type 2B. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Mar 2009]
Synonyms AMCD2B; DA2B; FSSV; fsTnI
Reference Data
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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