ID1 (Center) Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	FC, IF, IHC, WB
Recommend Dilution	ELISA: 1/1000.  Western Blot: 1/100-1/500.  Flow Cytometry: 1/10-1/50.   Immunofluorescence: 1/10-1/50.   Immunohistochemistry on Paraffin Sections: 1/10-1/50.
Reactivity	Human, Mouse
Host	Rabbit
Clonality	Polyclonal
Immunogen	KLH conjugated synthetic peptide between 73-101 amino acids from the Central region of Human ID1 / BHLHB24
Specificity	This antibody recognizes Human and Mouse ID1 / BHLHB24 (Center).
Formulation	PBS containing 0.09% (W/V) Sodium Azide as preservative State: Aff - Purified State: Liquid purified Ig fraction
Concentration	lot specific
Purification	Protein A column, followed by peptide affinity purification
Conjugation	Unconjugated
Storage Condition	Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing.
Gene Name	inhibitor of DNA binding 1, HLH protein
Database Link	Entrez Gene 15901 MouseEntrez Gene 3397 Human UniProt ID P41134
Background	The protein encoded by this gene is a helix-loop-helix (HLH) protein that can form heterodimers with members of the basic HLH family of transcription factors. The encoded protein has no DNA binding activity and therefore can inhibit the DNA binding and transcriptional activation ability of basic HLH proteins with which it interacts. This protein may play a role in cell growth, senescence, and differentiation. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq].
Synonyms	DNA-binding protein inhibitor ID-1, Inhibitor of DNA binding 1
Note	Molecular Weight: 16133 Da
Reference Data
Protein Families	Druggable Genome, Transcription Factors
Protein Pathways	TGF-beta signaling pathway

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