CYP2A7 (Center) Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	FC, IHC, WB
Recommend Dilution	Flow cytometry: 1/10-1/50. Immunohistochemistry on Paraffin sections: 1/50-1/100. Western blot: 1/100-1/500. Enzyme immunoassay:  1/1000.
Reactivity	Human
Host	Rabbit
Clonality	Polyclonal
Immunogen	Synthetic peptide - KLH conjugated - corresponding to the central regio (between 128-15aa) of human CYP2A7.
Specificity	This antibody recognizes CYP2A7.
Formulation	PBS with 0.09% (W/V) Sodium azide State: Aff - Purified State: Liquid purified Ig fraction
Concentration	lot specific
Purification	Purified through a Protein A column followed by peptide affinity purification
Conjugation	Unconjugated
Storage Condition	Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing.
Gene Name	cytochrome P450 family 2 subfamily A member 7
Database Link	Entrez Gene 1549 Human UniProt ID P20853
Background	CYP2A7 is a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum; its substrate has not yet been determined. CYP2A7, which produces two transcript variants, is part of a large cluster of cytochrome P450 genes from the CYP2A, CYP2B and CYP2F subfamilies on chromosome 19q.
Synonyms	Cytochrome P450 2A7, CYPIIA7, Cytochrome P450-IIA4
Note	Molecular Weight: 56425 Da
Reference Data
Protein Families	Druggable Genome, P450, Transmembrane
Protein Pathways	Caffeine metabolism, Drug metabolism - cytochrome P450, Drug metabolism - other enzymes, Metabolic pathways, Retinol metabolism

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