Col17a1 Rabbit Polyclonal Antibody

CAT#: AP23435PU-N

Col17a1 rabbit polyclonal antibody, Purified



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CNY 7,887.00


货期*
5周

规格
    • 100 ug

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Specifications

Product Data
Applications IF, IHC
Recommend Dilution Immunofluorescence.
Immunohistochemistry on Cryosections.
Reactivity Mouse
Host Rabbit
Clonality Polyclonal
Immunogen Mouse COL17A
Specificity Recognizes Mouse Collagen type XVII. Other species not tested.
Formulation PBS pH 7.4
State: Purified
State: Lyophilized purified IgG fraction from Serum
Reconstitution Method Restore in 100µl aqua bidest.
Purification Protein G Chromatography
Conjugation Unconjugated
Storage Condition Store lyophilized at 2-8°C for 6 months or at -20°C long term.
After reconstitution store the antibody undiluted at 2-8°C for one month 
or (in aliquots) at -20°C long term.
Avoid repeated freezing and thawing.
Gene Name collagen, type XVII, alpha 1
Background Unlike most collagens, collagen XVII is a transmembrane protein. Collagen XVII is a structural component of hemidesmosomes, multiprotein complexes at the dermal epidermal basement membrane zone that mediate adhesion of keratinocytes to the underlying membrane. Mutations in the gene coding for collagen XVII are associated with both generalized atrophic benign and junctional epidermolysis bullosa. Two homotrimeric forms of type XVII collagen exist. The full length form is the transmembrane protein. A soluble form, referred to as either ectodomain or LAD 1, is generated by proteolytic processing of the full length form. Two transcript variants, one resulting from alternative splicing in the 3' UTR, have been identified for this gene.
Synonyms COL17A1, BP180, BPAG2, Bullous pemphigoid antigen 2, LAD-1, LABD97
Reference Data
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.
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