Cathepsin G (CTSG) Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	IHC, WB
Recommend Dilution	Western blot: 1/500-1/1000. Immunohistochemistry on Paraffin Sections: 1/50-1/200.
Reactivity	Human
Host	Rabbit
Clonality	Polyclonal
Immunogen	Synthetic peptide, corresponding to amino acids 71-120 of Human Cathepsin G.
Specificity	This antibody detects endogenous levels of Cathepsin G protein. (region surrounding Arg116)
Formulation	PBS, pH 7.2 State: Aff - Purified State: Liquid purified Ig fraction (> 95% by SDS-PAGE) Preservative: 15 mM Sodium Azide
Concentration	1.0 mg/ml
Purification	Affinity Chromatography using epitope-specific immunogen
Conjugation	Unconjugated
Storage Condition	Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing.
Predicted Protein Size	~ 30 kDa
Gene Name	cathepsin G
Database Link	Entrez Gene 1511 Human UniProt ID P08311
Background	Cathepsin G is a serine protease, it consisting of a single polypeptide with a molecular weight of 30 kDa as determined by SDS-PAGE. Its substrates are collagen and proteoglycans. Poor regulation of Cathepsin G levels has been associated with various connective tissue disorders, for example pulmonary emphysema and cystic fibrosis.
Synonyms	CTSG, VSP
Reference Data
Protein Families	Druggable Genome, Protease
Protein Pathways	Lysosome, Neuroactive ligand-receptor interaction, Renin-angiotensin system, Systemic lupus erythematosus

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