GFAP (417-430) Goat Polyclonal Antibody

CAT#: AP08522PU-N

GFAP (417-430) goat polyclonal antibody, Aff - Purified



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CNY 5,654.00


货期*
5周

规格
    • 50 ug

Product images

Specifications

Product Data
Applications ELISA, IHC, WB
Recommend Dilution ELISA: 1/32000.
Immunohistochemistry on Paraffin Sections: 5 µg/ml.
Western Blot: 1 - 3 µg/ml.
Reactivity Human, Rat, Canine, Mouse, Bovine, Bat, Equine, Monkey, Rabbit
Host Goat
Clonality Polyclonal
Immunogen Synthetic peptide from the C-terminus of Human GFAP
Specificity This antibody recognizes Glial Fibrillary Acidic Protein (GFAP) at aa 417-430.
Formulation Tris-buffered saline, pH 7.3, 0.5% BSA, 0.02% sodium azide
State: Aff - Purified
State: Liquid purified Ig fraction
Concentration lot specific
Purification Immunoaffinity Chromatography
Conjugation Unconjugated
Storage Condition Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
Avoid repeated freezing and thawing.
Gene Name glial fibrillary acidic protein
Background Glial fibrillary acidic protein (GFAP) is a member of the class III intermediate filament protein family. It is heavily, and specifically, expressed in astrocytes and certain other astroglia in the central nervous system, in satellite cells in peripheral ganglia, and in non myelinating Schwann cells in peripheral nerves. In addition, neural stem cells frequently strongly express GFAP. Antibodies to GFAP are therefore very useful as markers of astrocytic cells. In addition many types of brain tumor, presumably derived from astrocytic cells, heavily express GFAP. GFAP is also found in the lens epithelium, Kupffer cells of the liver, in some cells in salivary tumors and has been reported in erythrocytes.
In the central nervous system, this antibody stains astrocytes and some groups of ependymal cells. However, in the peripheral nervous system, it stains Schwann cells, satellite cells and enteric glial cells.
Synonyms Glial Fibrillary Acidic Protein
Reference Data
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.
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