DAB1 Rabbit Polyclonal Antibody

CAT#: AP02753PU-S

DAB1 rabbit polyclonal antibody, Aff - Purified

Size: 50 ul 100 ul



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CNY 1,400.00


货期*
2周

规格
    • 50 ul

Product images

Specifications

Product Data
Applications IHC
Recommend Dilution Immunohistochemistry: 1:50-1:100.
Reactivity Human, Mouse, Rat
Host Rabbit
Clonality Polyclonal
Immunogen The antiserum was produced against synthesized non-phosphopeptide derived from human Dab1around the phosphorylation site of tyrosine 232 (G-V-YP-D-V).
Specificity Dab1 antibody detects endogenous levels of total Dab1 protein.
Formulation PBS (without Mg2+ and Ca2+), pH 7.4 containing 150mM NaCl, 0.02% sodium azide and 50% glycerol
State: Aff - Purified
State: Liquid purified IgG
Concentration lot specific
Purification The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
Conjugation Unconjugated
Storage Condition Store the antibody at -20°C.
Avoid repeated freezing and thawing.
Gene Name DAB1, reelin adaptor protein
Background Disruption of DAB 1 (Disable 1) results in aberrant migration of neurons during development and disorganization of laminar structures throughout the brain. Dab1 is thought to function as an adaptor molecule in signal transduction processes. It contains a protein protein interaction (PI) similar to the phosphotyrosine binding domain of the Shc oncoprotein, it is phosphorylated by the Src protein tyrosine kinase, and it binds to SH2 binding domains in a phosphotyrosine dependent manner. DAB1 acts downstream of reelin in a signalling pathway.
Synonyms Disabled homolog 1
Reference Data
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.
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