AKT2 pSer474 Rabbit Polyclonal Antibody

CAT#: AP02412PU-S

AKT2 pSer474 rabbit polyclonal antibody, Aff - Purified

Size: 50 ul 100 ul



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CNY 1,400.00


货期*
2周

规格
    • 50 ul

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Specifications

Product Data
Applications IHC, WB
Recommend Dilution Suitable for use in Western blot (1:500~1:1000) and Immunohistochemistry (1:50~1:100).
Reactivity Human, Mouse
Host Rabbit
Clonality Polyclonal
Immunogen The antiserum was produced against synthesized phosphopeptide derived from human Akt2 around the phosphorylation site of serine 474 (Q-F-SP-Y-S).
Specificity The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific phosphopeptide. The antibody against non-phosphopeptide was removed by chromatography using non-phosphopeptide corresponding to the phosphorylation site.
Akt2 (phospho-Ser474) antibody detects endogenous levels of Akt2 only when phosphorylated at serine 474.
Formulation PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02% Sodium Azide and 50% Glycerol.
State: Aff - Purified
State: Liquid purified Ig fraction.
Concentration lot specific
Purification Immunoaffinity chromatography.
Conjugation Unconjugated
Storage Condition Store the antibody (in aliquots) at -20°C.
Avoid repeated freezing and thawing.
Gene Name AKT serine/threonine kinase 2
Background The serine/threonine kinase Akt (protein kinase B or PKB) has a central role in the regulation of several signaling pathways controlling cell proliferation, apoptosis, angiogenesis, and diabetes. In humans, there are three genes in the "Akt family": Akt1, Akt2, and Akt3.
AKT2 is a putative oncogene and is a general protein kinase capable of phophorylating several known proteins. AKT2 is amplified and overexpressed in some human carcinomas. AKT2 acts primarily as a regulator of glucose metabolism.
Synonyms RAC-PK-beta, Protein kinase Akt-2, Protein kinase B beta
Reference Data
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.
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