Emilin1 Rat Monoclonal Antibody [Clone ID: C11A8]

Specifications

Product Data
Clone Name	C11A8
Applications	IF, IHC, WB
Recommend Dilution	Western Blot: 2-10 µg/ml.  Immunofluorescence. Immunohistochemistry on Frozen Sections.
Reactivity	Mouse
Host	Rat
Clonality	Monoclonal
Immunogen	Recombinant Mouse Emilin-1
Specificity	This antibody was selected for its ability to detect Murine Emilin-1.
Formulation	PBS State: Purified State: Lyophilized (0.2 μm filtered) purified IgG fraction
Reconstitution Method	Restore in sterile water to a concentration is 0.1-1.0 mg/ml. Centrifuge vial prior to opening.
Purification	Affinity Chromatography on Protein G
Conjugation	Unconjugated
Storage Condition	Prior to reconstitution store at 2-8°C for one month or at -20°C for longer. Following reconstitution store undiluted at 2-8°C for one month  or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing.
Gene Name	elastin microfibril interfacer 1
Database Link	Entrez Gene 100952 Mouse UniProt ID Q99K41
Background	Emilin-1 is an extracellular matrix glycoprotein localized at sites where elastin and microfibrils are in proximity. It may be responsible for anchoring smooth muscle cells to elastic fibers. It has cell adhesive capacity. Emilin-1 may have a role in the regulation of blood vessel assembly since it inhibits TGFB signaling by binding specifically to the pro-TGFB precursor and preventing its maturation by furin convertases in the extracellular space. TGFB proteins are the main regulators of blood vessel development and maintenance.
Synonyms	EMILIN-1, EMI
Reference Data

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