ICAM2 Mouse Monoclonal Antibody [Clone ID: B-T1]

Specifications

Product Data
Clone Name	B-T1
Applications	FC, FN, IP
Recommend Dilution	Fuctional Assay: Inhibits cell adhesion and T cell activition. Flow Cytometry. Immunoprecipitation.
Reactivity	Human
Host	Mouse
Clonality	Monoclonal
Immunogen	ICAM-2 transfected CHO cells.
Specificity	Recognises soluble antigen. Recognises the Intercellular Adhesion Molecule-2 (ICAM-2), a 55-65 kDa protein.
Formulation	PBS, Sterile-filtered through 0.22 µm. Carrier and preservative free State: Azide Free State: Liquid purified IgG fraction
Concentration	lot specific
Purification	Ion Exchange Chromatography
Conjugation	Unconjugated
Storage Condition	Store the antibody undiluted at 2-8°C.
Gene Name	intercellular adhesion molecule 2
Database Link	Entrez Gene 3384 Human UniProt ID P13598
Background	ICAM2 is a member of the intercellular adhesion molecule (ICAM) family. All ICAM proteins are type I transmembrane glycoproteins, contain 2-9 immunoglobulin like C2 type domains, and bind to the leukocyte adhesion LFA1 protein. This protein may play a role in lymphocyte recirculation by blocking LFA1 dependent cell adhesion. It mediates adhesive interactions important for antigen specific immune response, NK cell mediated clearance, lymphocyte recirculation, and other cellular interactions important for immune response and surveillance.
Synonyms	ICAM-2
Reference Data
Protein Families	ES Cell Differentiation/IPS, Transmembrane
Protein Pathways	Cell adhesion molecules (CAMs), Natural killer cell mediated cytotoxicity

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