LAMP2 Mouse Monoclonal Antibody [Clone ID: H4B4]

CAT#: AM08170FC-N

LAMP2 mouse monoclonal antibody, clone H4B4, FITC

Conjugation: Unconjugated Biotin FITC PE



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CNY 4,136.00


货期*
4周

规格
    • 100 Tests

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Specifications

Product Data
Clone Name H4B4
Applications FC
Recommend Dilution Flow Cytometry: 10 µL/10e6 cells.
Reactivity Human
Host Mouse
Clonality Monoclonal
Specificity This antibody recognizes CD107b/LAMP-2.
Formulation PBS containing 0.09% Sodium Azide as preservative.
Label: FITC
State: Liquid purified Ig fraction.
Label: Fluorescein Isothiocyanate Isomer 1
Conjugation FITC
Storage Condition Store the antibody undiluted at 2-8°C for one month or in (aliquots) at -20°C for longer.
This product is photosensitive and should be protected from light.
Avoid repeated freezing and thawing.
Gene Name lysosomal associated membrane protein 2
Background CD107b, also known as lysosomal-associated membrane protein 2 (LAMP-2), is a heavily glycosylated, type I transmembrane protein that constitutes the major sialoglycoproteins on lysosomal membranes. It is a ligand for galaptin, an S-type lectin present in extracellular matrix, through its recognition of acetyllactosamine oligosaccharide chains, and is a ligand for E-selectin-mediated cell adhesion.
CD107b is expressed by granulocytes, T cells, macrophages, dendritic cells, activated platelets tonsillar epithelium and some tumor cell lines, including U937 and KG1a. It is also a widely expressed intracellular antigen. LAMP-2 may function in protecting the inner surface of the lysosomal membrane by forming a barrier to lysosomal hydrolases. The upregulation of both CD107a and CD107b on the surface of tumor cell lines has been associated with their enhanced metastatic potential, where they may increase adhesion to extracellular matrix and endothelium. (Ref.1-7)
Synonyms LAMP-2, LAMP-2C, LAMPB
Reference Data
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.
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